Salp15, a 15-kDa tick salivary gland protein, has several suppressive modes of activity against host immunity and plays a critical role in the transmission of Lyme disease spirochetes in Ixodes scapularis and Ixodes ricinus, major vectors of Lyme disease in North America and Western Europe. Salp1...
Murase, Y.
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Konnai, S.
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Yamada, S.
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Githaka, Naftaly W.
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Isezaki, M.
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Ito, T.
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Takano, A.
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Ando, S.
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Kawabata, H.
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Murata, S.
,
Ohashi, K.
,
[An investigation of binding ability of Ixodes persulcatus Schulze Salp15 with Lyme disease spirochetes]
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An investigation of binding ability of Ixodes persulcatus Schulze Salp15 with Lyme disease spirochetes
Ixodes ricinus immunosuppressor (Iris) is a tick salivary gland protein derived from I. ricinus. In this study, Iris homolog was identified in the salivary glands of Ixodes persulcatus, which is the specific vector of the Lyme disease agent in Japan. The homolog was named Ipis-1. To investigate t...
Toyomane, K.
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Konnai, S.
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Niwa, A.
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Githaka, Naftaly W.
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Isezaki, M.
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Yamada, S.
,
Ito, T.
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Takano, A.
,
Ando, S.
,
Kawabata, H.
,
Murata, S.
,
Ohashi, K.
,
[Identification and the preliminary in vitro characterization of IRIS homologue from salivary glands of Ixodes persulcatus Schulze]
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Identification and the preliminary in vitro characterization of IRIS homologue from salivary glands of Ixodes persulcatus Schulze
Background Although vector control strategies, such as insecticide-treated bed nets (ITNs) and indoor residual spraying (IRS) have been effective in Kenya the transmission of malaria continues to afflict western Kenya. This residual transmission is driven in part by Anopheles arabiensis, known fo...
Lozano-Fuentes, Saul
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Kading, R.C.
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Hartman, D.A.
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Okoth, Edward A.
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Githaka, Naftaly W.
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Nene, Vishvanath
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Poche, R.M.
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[Evaluation of a topical formulation of eprinomectin against Anopheles arabiensis when administered to Zebu cattle (Bos indicus) under field conditions]
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Evaluation of a topical formulation of eprinomectin against Anopheles arabiensis when administered to Zebu cattle (Bos indicus) under field conditions
In this work we evaluated several genes involved in gluconeogenesis, glycolysis and glycogen metabolism, the major pathways for carbohydrate catabolism and anabolism, in the BME26 Rhipicephalus microplus embryonic cell line. Genetic and catalytic control of the genes and enzymes associated with t...
Silatsa, Barberine A.
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Simo, Gustave
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Githaka, Naftaly W.
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Mwaura, Stephen
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Kamga, Rolin M.
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Oumarou, Fariikou
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Tiambo, Christian K.
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Bishop, Richard P.
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Djikeng, Appolinaire
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Kuiate, Jules-Roger
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Njiokou, Flobert
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Pelle, Roger
,
[A comprehensive survey of the prevalence and spatial distribution of ticks infesting cattle in different agro-ecological zones of Cameroon]
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A comprehensive survey of the prevalence and spatial distribution of ticks infesting cattle in different agro-ecological zones of Cameroon
Piroplasms frequently infect domestic and wild carnivores. At present, there is limited information on the occurrence and molecular identity of these tick-borne parasites in wild felids in Kenya. In 2009, a pair of captive lions (Panthare leo) was diagnosed with suspected babesiosis and mineral d...
Githaka, Naftaly W.
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Konnai, S.
,
Kariuki, E.
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Kanduma, E.G.
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Murata, S.
,
Ohashi, K.
,
[Molecular detection and characterisation of potentially new Babesia and Theileria species/variants in wild felids from Kenya]
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Molecular detection and characterisation of potentially new Babesia and Theileria species/variants in wild felids from Kenya
Silatsa, Barberine A.
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Kuiate, Jules-Roger
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Njiokou, F.
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Simo, G.
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Feussom, J.-M.K.
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Tunrayo, A.
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Amzati, Gaston S.
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Bett, Bernard K.
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Bishop, R.
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Githaka, Naftaly W.
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Opiyo, S.O.
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Djikeng, Appolinaire
,
Pelle, Roger
,
[A countrywide molecular survey leads to a seminal identification of the invasive cattle tick Rhipicephalus (Boophilus) microplus in Cameroon, a decade after it was reported in Cote d’Ivoire]
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A countrywide molecular survey leads to a seminal identification of the invasive cattle tick Rhipicephalus (Boophilus) microplus in Cameroon, a decade after it was reported in Cote d’Ivoire
The transcriptional control of gene expression is not well documented in the Arthropoda. We describe transcriptional analysis of two exceptionally divergent homologues (Ra86) of the Bm86 gut antigen from Rhipicephalus appendiculatus. Bm86 forms the basis of a commercial vaccine for the control of...
Kamau, L.
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Skilton, Robert A.
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Odongo, David O.
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Mwaura, S.
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Githaka, Naftaly W.
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Kanduma, E.G.
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Obura, M.
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Kabiru, E.
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Orago, A.
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Musoke, A.J.
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Bishop, Richard P.
,
[Differential transcription of two highly divergent gut-expressed Bm86 antigen gene homologues in the tick Rhipicephalus appendiculatus (Acari: Ixodida)]
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Differential transcription of two highly divergent gut-expressed Bm86 antigen gene homologues in the tick Rhipicephalus appendiculatus (Acari: Ixodida)
Recently, mortalities among giraffes, attributed to infection with unique species of piroplasms were reported in South Africa. Although haemoparasites are known to occur in giraffes of Kenya, the prevalence, genetic diversity and pathogenicity of these parasites has not been investigated.
In thi...
Githaka, Naftaly W.
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Konnai, S.
,
Skilton, Robert A.
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Kariuki, E.
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Kanduma, E.G.
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Murata, S.
,
Ohashi, K.
,
[Genotypic variations in field isolates of Theileria species infecting giraffes (Giraffa camelopardalis tippelskirchi and Giraffa camelopardalis reticulata) in Kenya]
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Genotypic variations in field isolates of Theileria species infecting giraffes (Giraffa camelopardalis tippelskirchi and Giraffa camelopardalis reticulata) in Kenya
Background
The ixodid tick Rhipicephalus appendiculatus transmits the apicomplexan protozoan parasite Theileria parva,which causes East coast fever (ECF), the most economically important cattle disease in eastern and southern Africa. Recent analysis of micro- and minisatellite markers showed an a...
Kanduma, E.G.
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Mwacharo, Joram M.
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Githaka, Naftaly W.
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Kinyanjui, P.W.
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Njuguna, J.
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Kamau, L.M.
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Kariuki, E.
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Mwaura, S.
,
Skilton, Robert A.
,
Bishop, Richard P.
,
[Analyses of mitochondrial genes reveal two sympatric but genetically divergent lineages of Rhipicephalus appendiculatus in Kenya]
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Analyses of mitochondrial genes reveal two sympatric but genetically divergent lineages of Rhipicephalus appendiculatus in Kenya