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The transcriptional control of gene expression is not well documented in the Arthropoda. We describe transcriptional analysis of two exceptionally divergent homologues (Ra86) of the Bm86 gut antigen from Rhipicephalus appendiculatus. Bm86 forms the basis of a commercial vaccine for the control of...


Kamau, L.Skilton, Robert A.Odongo, David O.Mwaura, S.Githaka, Naftaly W.Kanduma, E.G.Obura, M.Kabiru, E.Orago, A.Musoke, A.J.Bishop, Richard P.[Differential transcription of two highly divergent gut-expressed Bm86 antigen gene homologues in the tick Rhipicephalus appendiculatus (Acari: Ixodida)]Differential transcription of two highly divergent gut-expressed Bm86 antigen gene homologues in the tick Rhipicephalus appendiculatus (Acari: Ixodida)

Among arthropods, ticks lead as vectors of animal diseases and rank second to mosquitoes in transmitting human pathogens. Cyclin-dependent kinases (CDK) participate in cell cycle control in eukaryotes. CDKs are serine/threonine protein kinases and these catalytic subunits are activated or inactiv...


Gomes, H.Moraes, J.Githaka, Naftaly W.Martins, R.Isezaki, M.Silva Vaz, I. daLogullo, C.Konnai, S.Ohashi, K.[Vaccination with cyclin-dependent kinase tick antigen confers protection against Ixodes infestation]Vaccination with cyclin-dependent kinase tick antigen confers protection against Ixodes infestation
Oyugi, M.O.Kinyua, J.K.Magiri, E.N.Kigoni, M.W.Costa, E.P.Githaka, Naftaly W.[In silico characterization and structural modeling of Dermacentor andersoni p36 immunosuppressive protein]In silico characterization and structural modeling of Dermacentor andersoni p36 immunosuppressive protein

The ticks Rhipicephalus appendiculatus and Rhipicephalus sanguineus are the main vectors of Theileria parva and Babesia spp. in cattle and dogs, respectively. Due to their impact in veterinary care and industry, improved methods against R. appendiculatus and R. sanguineus parasitism are under dev...


Sabadin, G.A.Parizi, L.F.Kiio, I.Xavier, M.A.Silva Matos, R. daCamargo-Mathias, M.I.Githaka, Naftaly W.Nene, VishvanathSilva Vaz, I. da[Effect of recombinant glutathione S-transferase as vaccine antigen against Rhipicephalus appendiculatus and Rhipicephalus sanguineus infestation]Effect of recombinant glutathione S-transferase as vaccine antigen against Rhipicephalus appendiculatus and Rhipicephalus sanguineus infestation

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