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East coast fever (ECF) is a major tick-borne disease caused by the apicomplexan parasite Theileria parva (1). ECF is an acute leukemia-like disease of cattle that is endemic in eastern, central and souther Africa, where it is responsible for significant mortality and losses in animal production. ...


Grab, D.J.Naessens, JanOle-MoiYoi, O.K.[Evidence for ADP-ribosylation and G protein in Theileria parva-transformed bovine lymphocytes]Evidence for ADP-ribosylation and G protein in Theileria parva-transformed bovine lymphocytes

Various parasitic protozoa of the family Trypanosomatidae such as Crithidia spp. [1]; Trypanosoma cruzi [2]; Leishmania donovani [3] and salivarian trypanosomes [4-8] have been shown to contain acid phosphatase activity (EC.3.1.3.2, orthophosphoric-monoester phosphohydrolase activity). Acid phosp...


Grab, D.J.Webster, P.Verjee, Y.Lonsdale-Eccles, J.[Golgi-associated phosphohydrolases in Trypanosoma brucei brucei]Golgi-associated phosphohydrolases in Trypanosoma brucei brucei

The membrane-associated form of the variable surface glycoprotein (mfVSG) from African trypanosomes is a potent macrophage activator capable of inducing production of tumor necrosis factor z (TNFalfa) in both bovine and murine models. Using a bovine model. we have re-investigated the hypothesis t...


Sileghem, M.R.Saya, R.Grab, D.J.Naessens, Jan[An accessory role for the diacylglycerol moiety of variable surface glycoprotein of African trypanosomes in the simulation of bovine monocytes]An accessory role for the diacylglycerol moiety of variable surface glycoprotein of African trypanosomes in the simulation of bovine monocytes
Webster, P.Grab, D.J.[Intracellular localization of variant surface glycoprotein and transferrin-gold in Trypanosoma brucei]Intracellular localization of variant surface glycoprotein and transferrin-gold in Trypanosoma brucei
Grab, D.J.Webster, P.Ito, S.Fish, W.R.Verjee, Y.Lonsdale-Eccles, J.D.[Subcellular localization of a variable surface glycoprotein phosphatidylinostitol-specific phospholipase-C in African trypanosomes]Subcellular localization of a variable surface glycoprotein phosphatidylinostitol-specific phospholipase-C in African trypanosomes
Lonsdale-Eccles, J.D.Grab, D.J.[Purification of African trypanosomes can cause biochemical changes in the parasites]Purification of African trypanosomes can cause biochemical changes in the parasites
Nwagwu, M.Grab, D.J.Ole-MoiYoi, O.K.Hirumi, H.Watanabe, M.[Phosphofructokinase of Trypanosoma brucei. Purification and properties]Phosphofructokinase of Trypanosoma brucei. Purification and properties
Brown, W.C.Grab, D.J.[Biological and biochemical characterization of bovine interleukin. 2. Studies with cloned bovine T cells]Biological and biochemical characterization of bovine interleukin. 2. Studies with cloned bovine T cells

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