Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated through the destruction of parasite infected lymphocytes by MHC class I restricted CD8+ CTL. Six parasite proteins targeted by CTL from T. parva immune cattle have been identified and raised...
Graham, S.P.
,
Pelle, Roger
,
Villiers, Etienne P. de
,
Yamage, M.
,
Mwangi, D.M.
,
Honda, Y.
,
Ellis, S.A.
,
MacHugh, Niall D.
,
Morrison, W. Ivan
,
Taracha, E.L.N.
,
[Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva]
,
Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva
Enhancement of the induction of cytotoxic T-cell responses by immunostimulatory CpG oligodeoxynucleotides has been described in humans and mouse models. The present study attempted to address whether CpG has a similar effect in cattle. Immunisation of cattle with a recombinant form of the polymor...
Graham, S.P.
,
Saya, R.
,
Awino, Elias
,
Ngugi, D.
,
Nyanjui, J.K.
,
Hecker, R.
,
Taracha, E.L.N.
,
Nene, Vishvanath
,
[Immunostimulatory CpG oligodeoxynucleotides enhance the induction of bovine CD4+ cytotoxic T-lymphocyte responses against the polymorphic immunodominant molecule of the protozoan parasite Theileria parva]
,
Immunostimulatory CpG oligodeoxynucleotides enhance the induction of bovine CD4+ cytotoxic T-lymphocyte responses against the polymorphic immunodominant molecule of the protozoan parasite Theileria parva
Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated by CD8 T cells. Six antigens targeted by CD8 T cells from T. parva-immune cattle of different major histocompatibility complex (MHC) genotypes have been identified, raising the prospect of d...
Graham, S.P.
,
Pelle, Roger
,
Yamage, M.
,
Mwangi, D.M.
,
Honda, Y.
,
Mwakubambanya, R.S.
,
Villiers, Etienne P. de
,
Abuya, E.
,
Awino, Elias
,
Gachanja, J.
,
Mbwika, F.
,
Muthiani, A.M.
,
Muriuki, C.
,
Nyanjui, J.K.
,
[Characterization of the fine specificity of Bovine CD8 T-Cell responses to defined antigens from the protozoan parasite Theileria parva]
,
Characterization of the fine specificity of Bovine CD8 T-Cell responses to defined antigens from the protozoan parasite Theileria parva