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Objective: Metabolic syndrome (MetS) is associated with hypertension, obesity and dyslipidemia. Thus, genetic variants related with these conditions may modulate its development. We evaluated the effect of polymorphisms in the renin-angiotensin system (RAS) on metabolic syndrome risk in a cohort ...


Herrera, Christian L.Castillo, WilmaEstrada, PatriciaMancilla, BarbaraReyes, GerardoSaavedra, NicolasGuzman Oyarzo, NeftaliSeron, PamelaLanas, FernandoSalazar, Luis A.[Association of polymorphisms within the Renin-Angiotensin System with metabolic syndrome in a cohort of Chilean subjects]Association of polymorphisms within the Renin-Angiotensin System with metabolic syndrome in a cohort of Chilean subjects
Letelier, PabloGuzman Oyarzo, NeftaliMedina Schwerter, GustavoCalcumil, LuisHuencho, PamelaMora, JonathanQuinones, FranciscoJara, JorgeReyno, CristobalFarias, Jorge G.Herrera Belen, BelenBrebi, PriscillaRiquelme, IsmaelSan Martin, Andres[WORKFLOW OPTIMIZATION IN A CLINICAL LABORATORY USING LEAN MANAGEMENT PRINCIPLES IN THE PRE-ANALYTICAL PHASE]WORKFLOW OPTIMIZATION IN A CLINICAL LABORATORY USING LEAN MANAGEMENT PRINCIPLES IN THE PRE-ANALYTICAL PHASE

Background: Alloimmunization is an adverse effect of blood transfusions. In Chile, alloimmunization frequency is not established, and for this reason the aim of this study was to investigate the prevalence and specificity of red blood cell (RBC) alloantibodies in Chilean transfused subjects. Meth...


Caamano, JoseMusante, EvangelinaContreras, MargaritaUlloa, HernanReyes, CarolinaInaipil, VeronicaSaavedra, NicolasGuzman Oyarzo, Neftali[Frequency and Specificity of Red Blood Cell Alloimmunization in Chilean Transfused Patients]Frequency and Specificity of Red Blood Cell Alloimmunization in Chilean Transfused Patients

Biliary tract cancers (BTCs) are a group of highly aggressive malignant tumors with a poor prognosis. The current diagnosis is based mainly on imaging and intraoperative exploration due to brush cytology having a low sensitivity and the standard markers, such as carcinoembryonic antigen (CEA) and...


Letelier, PabloRiquelme, IsmaelHernández Monsalves, AlfonsoGuzman Oyarzo, NeftaliFarias, Jorge G.Carlos Roa, Juan[Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers]Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers
Subiabre, ValeskaPalomo, IvanGuzman Oyarzo, NeftaliRetamales, EduardoHenriquez, HugoGonzalez, Luis[The Influence of Ethnicity on Warfarin Dosage Requirements in the Chilean Population]The Influence of Ethnicity on Warfarin Dosage Requirements in the Chilean Population

COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, which has given rise to a global sanitary emergency. The clinical characteristics of COVID-19 are varied and can range from an asymptomatic infection to a mild to severe pneumonia. Recent studies have shown that different laborator...


Letelier, PabloEncina, NicoleMorales, PabloRiffo, AlejandraSilva, HalettRiquelme, IsmaelGuzman Oyarzo, Neftali[ROLE OF BIOCHEMICAL MARKERS IN THE MONITORING OF COVID-19 PATIENTS]ROLE OF BIOCHEMICAL MARKERS IN THE MONITORING OF COVID-19 PATIENTS

There is an important interindividual variability in dose requirement for coumarinic anticoagulants, which could be explained by genetic and non-genetic factors. Among hereditary factors, there are gene polymorphisms that code the therapeutic target and the main enzyme responsible for their metab...


Guzman Oyarzo, NeftaliVega, MarioReyes, FrancoGuzman-Oyarzo, DinaAndaur Rademacher, MarcelaBoguen, RodrigoLetelier, Pablo[Pharmacogenomics of vitamin K antagonists]Pharmacogenomics of vitamin K antagonists

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