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Desmoglein 4 (DSG4) plays an important role in the regulation of growth and differentiation of hair follicles in mammals. In this study, a 755 bp long segment of DSG4 was screened in 544 sheep sampled from nine Chinese indigenous breeds and two Western breeds using PCR-SSCP assay with three diffe...


Yue-Hui MaGe, ZhangYuan-yue, ZhangWeijun, GuanQian-Jun ZhaoHui-jing, ZhaoHan Jianlin[Six SNPs and a TTG indel in sheep desmoglein 4 gene are in complete linkage disequilibrium]Six SNPs and a TTG indel in sheep desmoglein 4 gene are in complete linkage disequilibrium

Genotype data from eight microsatellite markers were used to assess genetic diversity and relationships among five indigenous Bhutanese sheep populations, Sakten, Jakar, Sarpang, Sipsu and Tsirang. Estimates of mean observed and expected heterozygosities, mean number of alleles per locus/populati...


Tashi, D.Wafula, P.Yoshio, Y.Shinji, S.Kenji, O.Hanotte, Olivier H.Bang-Zhong, L.Hideyuki, M.Han Jianlin[Sheep genetic diversity in Bhutan using microsatellite markers]Sheep genetic diversity in Bhutan using microsatellite markers
Zhang, GeZhang, Yuan-yueHan JianlinGuan, Wei-JunLi, Ying-kangXu, BinZhang, Xiu-taoMa, Yue-hui[Polymorphism of DSG4 gene and Its association with wool traits in fur sheep]Polymorphism of DSG4 gene and Its association with wool traits in fur sheep

An A/G Single Nucleotide Polymorphism (SNP) at position 1,892 of the Mx gene coding sequence has been linked to susceptibility/resistance to avian viral infection in vitro. Using PCR-RFLP and sequencing methods, 1,946 samples from 109 populations from Asia, Africa and Europe; grouped as indigenou...


Ommeh, S.Jin, L.N.Eding, H.Muchadeyi, F.C.Sulandari, S.Danbaro, G.Wani, C.E.Nie, Q.H.Zhang, X. Q.Ndila, M.Preisinger, R.Chen, G.H.Yousif, I. A.Heo, K.N.Oh, S.J.Tapio, M.Masiga, Daniel K.Hanotte, Olivier H.Weigend, S.Han Jianlin[Geographic and breed distribution patterns of an A/G Polymorphism resent in the Mx gene suggests balanced selection in village chickens]Geographic and breed distribution patterns of an A/G Polymorphism resent in the Mx gene suggests balanced selection in village chickens

Zhang, H.Y.Yang, W.J.Luo, Y.Z.Han Jianlin[Genetic polymorphisms in a 1.2 kb long fragment within intron 2 of chicken UBTD2 gene]Genetic polymorphisms in a 1.2 kb long fragment within intron 2 of chicken UBTD2 gene

Variants of kappa-casein (CSN3) have been extensively studied in cattle and 13 alleles have been identified at the protein and DNA levels to date. Evolution of some of these alleles and a possible common ancestor remain unclear. Polymerase chain reaction-single strand conformation polymorphism (P...


Prinzenberg, E.M.Erhardt, G.Han Jianlin[Genetic variation in the kappa-casein gene (CSN3) of Chinese yak (Bos grunniens) and phylogenetic analysis of CSN3 sequences in the genus Bos]Genetic variation in the kappa-casein gene (CSN3) of Chinese yak (Bos grunniens) and phylogenetic analysis of CSN3 sequences in the genus Bos

Global climate change has a significant effect on extreme environments and a profound influence on species survival. However, little is known of the genome-wide pattern of livestock adaptations to extreme environments over a short time frame following domestication. Sheep (Ovis aries) have become...


Ji YangWen-Rong LiFeng-Hua LvSan-Gang HeShi-Lin TianWei-Feng PengYa-Wei SunYong-Xin ZhaoXiao-Long TuMin ZhangXing-Long XieYu-Tao WangJin-Quan LiYong-Gang LiuZhi-Qiang ShenFeng WangGuang-Jian LiuHong-Feng LuJuha KantanenHan JianlinMeng-Hua LiMing-Jun Liu[Whole-genome sequencing of native sheep provides insights into rapid adaptations to extreme environments]Whole-genome sequencing of native sheep provides insights into rapid adaptations to extreme environments
An, T.W.Zhang, H.He, J.W.Feng, H.Y.Luo, Y.Z.Han Jianlin[Polymorphic but highly conserved Bogr-DRA gene in yak (Bos grunniens)]Polymorphic but highly conserved Bogr-DRA gene in yak (Bos grunniens)

Despite much attention, history of sheep (Ovis aries) evolution, including its dating, demographic trajectory and geographic spread, remains controversial. To address these questions, we generated 45 complete and 875 partial mitogenomic sequences, and performed a meta-analysis of these and publis...


Feng-Hua LvWei-Feng PengJi YangYong-Xin ZhaoWen-Rong LiMing-Jun LiuYue-Hui MaQian-Jun ZhaoGuang-Li YangFeng WangJin-Quan LiYong-Gang LiuZhi-Qiang ShenSheng-Guo ZhaoEEr HehuaGorkhali, N.A.Farhad Vahidi, S.M.Muladno, M.Naqvi, A.N.Tabell, J.Iso-Touru, T.Bruford, M.W.Kantanen, J.Han JianlinMeng-Hua Li[Mitogenomic meta-analysis identifies two phases of migration in the history of Eastern Eurasian sheep]Mitogenomic meta-analysis identifies two phases of migration in the history of Eastern Eurasian sheep

Domestic yak plays a critical role in supporting the livelihoods of nomads in the Central Asian Highlands. Tianzhu White yak is a unique breed developed from a very small number of mutant founders and its white hair has a special niche market value. In this study, the genetic polymorphisms in Tyr...


Zhang, H.An, T.W.He, J.W.Luo, Y.Z.Han Jianlin[Conserved exon 2 but a highly polymorphic 5'-UTR of Tyrosinase gene in Tianzhu White yak (Bos grunniens)]Conserved exon 2 but a highly polymorphic 5'-UTR of Tyrosinase gene in Tianzhu White yak (Bos grunniens)

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