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Cabrera, D.Gutiérrez, J.Cabello-Verrugio, C.Morales, M. G.Mezzano, S.Fadic, R.Casar, J. C.Hancke, J. L.Brandan, E.[Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis]Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis

Abstract Background Andrographis paniculata (A. paniculata), a medicinal plant, has shown anti-inflammatory, neuroprotective and antifibrotic effects in animal models as well as clinical efficacy in different studies, including an anti-fatigue effect...


Bertoglio, J. C.Baumgartner, M.Palma, R.Ciampi, EthelCárcamo, ClaudiaCáceres, D. D.Acosta-Jamett, G.Hancke, J. L.Burgos, R. A.[Andrographis paniculata decreases fatigue in patients with relapsing-remitting multiple sclerosis: a 12-month double-blind placebo-controlled pilot study]Andrographis paniculata decreases fatigue in patients with relapsing-remitting multiple sclerosis: a 12-month double-blind placebo-controlled pilot study

Background: Duchenne muscular dystrophy (DMD) is characterized by the absence of the cytoskeletal protein dystrophin, muscle wasting, increased transforming growth factor type beta (TGF-β) signaling, and fibrosis. At the present time, the only clinically validated treatments for DMD are glucocort...


Cabrera, D.Gutiérrez, J.Cabello-Verrugio, C.Morales, M. G.Mezzano, S.Fadic, R.Casar, J. C.Hancke, J. L.Brandan, E.[Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis]Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis

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