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A preliminary search for QTLs in a cattle F2 resource populations segregating for trypanotolerance has revealed three large candidate chromosomal regions (Bta02, Bta05, Bta07). In order to narrow down the position of the trypanotolerant QTLs, we are building comparative chromosomal maps between c...


Nilsson, P.H.Kang'a, S.Rottengatter, K.Suedbeck, U.Iraqui, F.Mwakaya, J.Mwangi, D.Womack, J.E.Goldammer, T.Schwerin, M.Bradley, D.Agaba, MorrisSugimoto, K.Gelhaus, A.Horstmann, R.Teale, A.J.Kemp, Stephen J.Hanotte, Olivier H.[Radiation hybrid maps of candidate trypanotolerance regions in cattle]Radiation hybrid maps of candidate trypanotolerance regions in cattle

We have sought to test the possibility of detecting regions of the genome under selection through effects on variation at linked neutral genetic markers. Particularly, we investigated three genomic regions identified by mapping in a cross-bred pedigree as harbouring QTL for trypanosomiasis tolera...


Park, S.D.E.Adomefa, K.Dao, B.Hanotte, Olivier H.Kemp, Stephen J.Sow, R.S.Teale, A.J.Bradley, D.G.[Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance]Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance
Tijjani, AbdulfataiUtsunomiya, Yuri TaniEzekwe, Arinze G.Nashiru, OyekanmiHanotte, Olivier H.[Genome sequence analysis reveals selection signatures in endangered trypanotolerant West African Muturu cattle]Genome sequence analysis reveals selection signatures in endangered trypanotolerant West African Muturu cattle

There have been significant evolutionary pressures on the chicken during both its speciation and its subsequent domestication by man. Infectious diseases are expected to have exerted strong selective pressures during these processes. Consequently, it is likely that genes associated with disease s...


Downing, T.Lynn, D.J.Connell, S.Lloyd, A.T.Bhuiyan, A.K.F.H.Silva, P.Naqvi, A.N.Sanfo, R.Sow, R.S.Overseas Development InstituteO'Farrelly, C.O.Hanotte, Olivier H.Bradley, D.G.[Contrasting evolution of diversity at two disease-associated chicken genes]Contrasting evolution of diversity at two disease-associated chicken genes

Some West African Bos taurus cattle breeds such as the N'Dama and a number of West African Shorthorns are resistant to tsetse fly-transmitted trypanosomosis. The trait is termed trypanotolerance, for which changes in packed red cell volume percent (PCV) and growth rate following infection are ge...


Waaij, E.H. van derHanotte, Olivier H.Arendonk, Johan A.M. vanKemp, Stephen J.Kennedy, D.Gibson, John P.Teale, A.J.[Population parameters for traits defining trypanotolerance in an F2 cross of N'Dama and Boran cattle]Population parameters for traits defining trypanotolerance in an F2 cross of N'Dama and Boran cattle

Genetic markers are being used by scientists worldwide in both animal and plant related breeding and Development efforts. The International Livestock Research Institute (ILRI) is a new institute formed in January 1995 by the amalgamation of the former ILCA (International Livestock Centre for Afri...


Tarawali, Shirley A.Rege, J.E.O.Hanotte, Olivier H.Hanson, Jean[DNA markers for forage and livestock improvement]DNA markers for forage and livestock improvement

Trypanosomiasis is one of the most important diseases in African cattle. About 3 million cattle die every year by this disease. However, about 5 percent of the total African cattle have a natural resistance against trypanosomiasis. In a preliminary study markers linked to trypanotolerance have be...


Goldammer, T.Brunner, R.M.Kang'a, S.Hanotte, Olivier H.Schwerin, M.[Generation of a bovine BAC pool for chromosome region BTA7q14-22 correlated to the trait trypanotolerance]Generation of a bovine BAC pool for chromosome region BTA7q14-22 correlated to the trait trypanotolerance

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