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Aguiar, T.S.Torrecilha, R.B.P.Milanesi, M.Utsunomiya, A.T.H.Trigo, B.B.Tijjani, A.Musa, H.H.Lopes, F.L.Ajmone-Marsan, P.Carvalheiro, R.Neves, H.H.R.Carmo, A.S. doHanotte, Olivier H.Sonstegard, T.S.García, J.F.Utsunomiya, Yuri Tani[Association of copy number variation at Intron 3 of HMGA2 with navel length in Bos indicus]Association of copy number variation at Intron 3 of HMGA2 with navel length in Bos indicus

A preliminary search for QTLs in a cattle F2 resource populations segregating for trypanotolerance has revealed three large candidate chromosomal regions (Bta02, Bta05, Bta07). In order to narrow down the position of the trypanotolerant QTLs, we are building comparative chromosomal maps between c...


Nilsson, P.H.Kang'a, S.Rottengatter, K.Suedbeck, U.Iraqui, F.Mwakaya, J.Mwangi, D.Womack, J.E.Goldammer, T.Schwerin, M.Bradley, D.Agaba, MorrisSugimoto, K.Gelhaus, A.Horstmann, R.Teale, A.J.Kemp, Stephen J.Hanotte, Olivier H.[Radiation hybrid maps of candidate trypanotolerance regions in cattle]Radiation hybrid maps of candidate trypanotolerance regions in cattle

We have sought to test the possibility of detecting regions of the genome under selection through effects on variation at linked neutral genetic markers. Particularly, we investigated three genomic regions identified by mapping in a cross-bred pedigree as harbouring QTL for trypanosomiasis tolera...


Park, S.D.E.Adomefa, K.Dao, B.Hanotte, Olivier H.Kemp, Stephen J.Sow, R.S.Teale, A.J.Bradley, D.G.[Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance]Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance

Background: The history of African indigenous cattle and their adaptation to environmental and human selection pressure is at the root of their remarkable diversity. Characterization of this diversity is an essential step towards understanding the genomic basis of productivity and adaptation to s...


Kim, JaeminHanotte, Olivier H.Okeyo Mwai, AllyDessie, TadelleSalim, BashirDiallo, BoubacarAgaba, MorrisKwondo KimWoori KwakSamsun SungSeo, MinseokJeong, HyeonsooKwon, TaehyungTaye, MengistieSong, Ki-DukLim, DajeongSeoae ChoLee, Hyun-JeongDuhak YoonSung Jong OhKemp, Stephen J.Hak-Kyo LeeHeebal Kim[The genome landscape of indigenous African cattle]The genome landscape of indigenous African cattle

Butana and Kenana are two types of zebu cattle found in Sudan. They are unique amongst African indigenous zebu cattle because of their high milk production. Aiming to understand their genome structure, we genotyped 25 individuals from each breed using the Illumina BovineHD Genotyping BeadChip. Ge...


Bahbahani, HussainSalim, B.Almathen, F.Al Enezi, F.Mwacharo, Joram M.Hanotte, Olivier H.[Signatures of positive selection in African Butana and Kenana dairy zebu cattle]Signatures of positive selection in African Butana and Kenana dairy zebu cattle

At least 150 indigenous African cattle breeds have been named, but the majority of African cattle populations remain largely uncharacterized. As cattle breeds and populations in Africa adapted to various local environmental conditions, they acquired unique features. We know now that the history o...


Okeyo Mwai, AllyHanotte, Olivier H.Young-Jun KwonSeoae Cho[African indigenous cattle: Unique genetic resources in a rapidly changing world]African indigenous cattle: Unique genetic resources in a rapidly changing world
Tijjani, AbdulfataiUtsunomiya, Yuri TaniEzekwe, Arinze G.Nashiru, OyekanmiHanotte, Olivier H.[Genome sequence analysis reveals selection signatures in endangered trypanotolerant West African Muturu cattle]Genome sequence analysis reveals selection signatures in endangered trypanotolerant West African Muturu cattle

An alternative approach for the direct analysis of chromosome regions corresponding to economical traits, based on chromosome microdissection, is described. Large fragment clones isolated with primer pairs designed from chromosome fragment-specific DNA sequences were localized by fluorescence in ...


Goldammer, T.Brunner, R.M.Kang'a, S.Hanotte, Olivier H.Schwerin, M.[Establishment of bovine chromosome region specific high resolution maps using microdissection]Establishment of bovine chromosome region specific high resolution maps using microdissection

Two bovine bacterial artificial chromosome clones were screened by PCR to amplify the tumour necrosis factor alpha (TNFA) gene. DNA extraction and Southern blotting and probing with a (GT)10 oligonucleotide were performed, followed by cloning into the pUC19 vector. A 0.9 kb fragment containing se...


Wambugu, J.Kanguha, E.Hanotte, Olivier H.Davis, S.Taylor, J.Skow, L.Brunner, R.Schwerin, M.Teale, A.J.Iraqi, F.A.[Identification of two polymorphic microsatellite repeats on a bovine TNFA-containing BAC clone]Identification of two polymorphic microsatellite repeats on a bovine TNFA-containing BAC clone

To evaluate the Weitzman approach for assessing alternative conservation strategies for breed ( population ) diversity, we used genetic distance measures between 49 African cattle breeds divided into two groups of 26 taurine ( Bos taurus ) and sanga ( Bos taurus×Bos indicus ) breeds and 23 zebu ...


Reist-Marti, S.B.Simianer, H.Gibson, John P.Hanotte, Olivier H.Rege, J.E.O.[Weitzman's approach and conservation of breed diversity: An application to African cattle breeds]Weitzman's approach and conservation of breed diversity: An application to African cattle breeds

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