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A number of linkage studies in human populations have identified a locus ( pfbi) on Chromosome 5q31-q33 controlling Plasmodiun falciparum blood infection levels. This region contains numerous candidate genes encoding immunological molecules such as cytokines, growth factors and growth-factor rec...


Hernández Valladares, M.Rihet, P.Ole-MoiYoi, O.K.Iraqi, F.A.[Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33]Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33

We have previously obtained strong evidence for linkage of mild malaria attack to the MHC region, with a peak close to the tumor necrosis factor (TNF) gene. We screened, for polymorphisms, the entire TNF gene in the same sample of 34 families comprising 197 individuals living in a Plasmodium falc...


Flori, L.Delahaye, N.F.Iraqi, F.A.Hernández Valladares, M.Fumoux, F.Rihet, P.[TNF as a malaria candidate gene: Polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso]TNF as a malaria candidate gene: Polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso

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