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A number of linkage studies in human populations have identified a locus ( pfbi) on Chromosome 5q31-q33 controlling Plasmodiun falciparum blood infection levels. This region contains numerous candidate genes encoding immunological molecules such as cytokines, growth factors and growth-factor rec...


Hernández Valladares, M.Rihet, P.Ole-MoiYoi, O.K.Iraqi, F.A.[Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33]Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33

We developed an F(11) AIL population from an F(1) cross of A/J (susceptible) and C57BL/6J (resistant) mouse strains. One thousand F(11) mice were challenged with P.c. chabaudi 54X, and 340 mice selected from the phenotypic extremes for susceptibility and resistance were genotyped for microsatel...


Hernández Valladares, M.Naessens, JanGibson, John P.Musoke, A.J.Nagda, S.M.Rihet, P.Ole-MoiYoi, O.K.Iraqi, F.A.[Confirmation and dissection of QTL controlling resistance to malaria in mice]Confirmation and dissection of QTL controlling resistance to malaria in mice

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