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Journal Article 2004

Autor: Sinyangwe, L. Delespaux, V. Brandt, J. Geerts, S. Mubanga, J. Machila, N. Holmes, P.H. Eisler, M.C.

A survey to investigate resistance to drugs used in the treatment of bovine trypanosomosis was conducted in the eastern province of Zambia between 1996 and 1998. A cross-sectional study was conducted in three districts (Petauke, Katete, Lundazi) at 34 village sampling sites selected at random fr...

Enlace original: https://cgspace.cgiar.org/handle/10568/33231

Investigación en Agricultura
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Sinyangwe, L. ,  Delespaux, V. ,  Brandt, J. ,  Geerts, S. ,  Mubanga, J. ,  Machila, N. ,  Holmes, P.H. ,  Eisler, M.C. ,  [Trypanocidal drug resistance in eastern province of Zambia] ,  Trypanocidal drug resistance in eastern province of Zambia
Conference Paper 2001

Autor: Geerts, S. Ndung'u, J.M. Murilla, G. Mbwambo, H. Sinyangwe, L. Machila, N. Delespaux, V. Brandt, J. Peregrine, A.S. McDermott, John J. Holmes, P.H. Eisler, M.C.

Testing of trypanocidal drug sensitivity in stabilates of pathogenic trypanosomes derived from cattle continues to be problematic, in spite of Development of in vitro techniques, since these are generally complicated and costly for the resources available in developing country laboratories. Furth...

Enlace original: https://cgspace.cgiar.org/handle/10568/50111

Investigación en Agricultura
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Geerts, S. ,  Ndung'u, J.M. ,  Murilla, G. ,  Mbwambo, H. ,  Sinyangwe, L. ,  Machila, N. ,  Delespaux, V. ,  Brandt, J. ,  Peregrine, A.S. ,  McDermott, John J. ,  Holmes, P.H. ,  Eisler, M.C. ,  [A simplified cost-effective method for area-wide testing of trypanocidal drug sensitivity of T. congolense in mice] ,  A simplified cost-effective method for area-wide testing of trypanocidal drug sensitivity of T. congolense in mice
Journal Article 2001

Autor: Eisler, M.C. Brandt, J. Bauer, B. Clausen, P.H. Delespaux, V. Holmes, P.H. Ilemobade, A. Machila, N. Mbwambo, H. McDermott, John J. Mehlitz, D. Murilla, G. Ndung'u, J.M. Peregrine, A.S. Sidibe, I. Sinyangwe, L. Geerts, S.

Resistance to the drugs used to control African animal trypanosomosis is increasingly recognised as a constraint to livestock production in sub-Saharan Africa. The most commonly used tests for detection of trypanocidal drug resistance are tests using mice or ruminants, but these suffer from lack ...

Enlace original: https://cgspace.cgiar.org/handle/10568/33255

Investigación en Agricultura
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Eisler, M.C. ,  Brandt, J. ,  Bauer, B. ,  Clausen, P.H. ,  Delespaux, V. ,  Holmes, P.H. ,  Ilemobade, A. ,  Machila, N. ,  Mbwambo, H. ,  McDermott, John J. ,  Mehlitz, D. ,  Murilla, G. ,  Ndung'u, J.M. ,  Peregrine, A.S. ,  Sidibe, I. ,  Sinyangwe, L. ,  Geerts, S. ,  [Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle] ,  Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle
Journal Article 2002

Autor: Murilla, G.A. Peregrine, A.S. Ndung'u, J.M. Holmes, P.H. Eisler, M.C.

Two groups of five Boran (Bos indicus) cattle were infected with one of two populations of Trypanosoma congolense; one drug-sensitive (IL1180), and one drug-resistant (IL3330). The animals were then treated intramuscularly with homidium bromide at a dose rate of 1.0 mg kg - bodyweight 7 days afte...

Enlace original: https://cgspace.cgiar.org/handle/10568/29979

Investigación en Agricultura
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Murilla, G.A. ,  Peregrine, A.S. ,  Ndung'u, J.M. ,  Holmes, P.H. ,  Eisler, M.C. ,  [The effects of drug-sensitive and drug-resistant Trypanosoma congolense infections on the pharmacokinetics of homidium in Boran cattle] ,  The effects of drug-sensitive and drug-resistant Trypanosoma congolense infections on the pharmacokinetics of homidium in Boran cattle
Conference Paper 2000

Autor: Eisler, M.C. McDermott, John J. Mdachi, R. Murilla, G. Sinyangwe, L. Mubanga, J. Machila, N. Mbwambo, H. Coleman, P.G. Clausen, P.H. Bauer, B. Sidibe, I. Geerts, S. Holmes, P.H. Peregrine, A.S.

Trypanocidal drugs are the most widely applied method of trypanosomosis control in Africa and the only control method in Latin America and Asia . Treatment recommendations and strategies for chemotherapeutic control of trypanosomosis depends on information of trypanosomosis risk and the prevalenc...

Enlace original: https://cgspace.cgiar.org/handle/10568/51007

Investigación en Agricultura
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Eisler, M.C. ,  McDermott, John J. ,  Mdachi, R. ,  Murilla, G. ,  Sinyangwe, L. ,  Mubanga, J. ,  Machila, N. ,  Mbwambo, H. ,  Coleman, P.G. ,  Clausen, P.H. ,  Bauer, B. ,  Sidibe, I. ,  Geerts, S. ,  Holmes, P.H. ,  Peregrine, A.S. ,  [Rapid method for the assessment of trypanocidal drug resistance in the field] ,  Rapid method for the assessment of trypanocidal drug resistance in the field
Conference Paper 2000

Autor: Eisler, M.C. Ndung'u, J.M. Murilla, G. Mdachi, R.M. Mbwambo, H. Sinyangwe, L. Machila, N. Delespaux, V. Geerts, S. Brandt, J. Peregrine, A.S. McDermott, John J. Holmes, P.H.

The extent and significance of trypanocidal drug resistance was investigated in priority areas of three East and Southern African Countries under a project. The project was built on the results of two previous projects. Existing methods currently available for the demonstration of drug-resistance...

Enlace original: https://cgspace.cgiar.org/handle/10568/50192

Investigación en Agricultura
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Eisler, M.C. ,  Ndung'u, J.M. ,  Murilla, G. ,  Mdachi, R.M. ,  Mbwambo, H. ,  Sinyangwe, L. ,  Machila, N. ,  Delespaux, V. ,  Geerts, S. ,  Brandt, J. ,  Peregrine, A.S. ,  McDermott, John J. ,  Holmes, P.H. ,  [Area-wide appraisal of drug resistance in trypanosomes infecting cattle in East and Southern Africa] ,  Area-wide appraisal of drug resistance in trypanosomes infecting cattle in East and Southern Africa
Conference Paper 2000

Autor: Geerts, S. Ndung'u, J.M. Murilla, G. Mbwambo, H. Sirryangwe, L. Machila, N. Delespaux, V. Brandt, J. Peregrine, A.S. McDermott, John J. Holmes, P.H. Eisler, M.C.

Besides the in vitro test, two tests are very commonly used for the detection of trypanocidal drug resistance: the tests in mice and in ruminants. Since it has been shown that several parameters such as the number of trypanosomes inoculated and the time of treatment might influence the outcome of...

Enlace original: https://cgspace.cgiar.org/handle/10568/50712

Investigación en Agricultura
Enlace permanente
Geerts, S. ,  Ndung'u, J.M. ,  Murilla, G. ,  Mbwambo, H. ,  Sirryangwe, L. ,  Machila, N. ,  Delespaux, V. ,  Brandt, J. ,  Peregrine, A.S. ,  McDermott, John J. ,  Holmes, P.H. ,  Eisler, M.C. ,  [In vivo tests for the detection of resistance to trypanocidal drugs: Tests in mice and in ruminants] ,  In vivo tests for the detection of resistance to trypanocidal drugs: Tests in mice and in ruminants

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