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Eisler, M.C.Arowolo, R.O.A.Gault, E.A.Moloo, S.K.Holmes, P.H.Peregrine, A.S.[Isometamidium concentrations in the sera of Boran cattle. Correlation with prophylaxis against tsetse-transmitted Trypanosoma congolense]Isometamidium concentrations in the sera of Boran cattle. Correlation with prophylaxis against tsetse-transmitted Trypanosoma congolense
Sutherland, I.A.Moloo, S.K.Holmes, P.H.Peregrine, A.S.[Therapeutic and prophylactic activity of isometamidium chloride against a tsetse-transmitted drug-resistant clone of Trypanosoma congolense in Boran cattle]Therapeutic and prophylactic activity of isometamidium chloride against a tsetse-transmitted drug-resistant clone of Trypanosoma congolense in Boran cattle

The relationship between serum concentrations of the prophylactic trypanocidal drug isometamidium chloride and protection against tsetse challenge with two populations of Trypanosoma congolense was investigated in Boran (Bos indicus) cattle, using an isometamidium-ELISA. Isometamidium chloride (S...


Eisler, M.C.Gault, E.A.Moloo, S.K.Holmes, P.H.Peregrine, A.S.[Concentrations of isometamidium in the sera of cattle challenged with drug-resistant Trypanosoma congolense]Concentrations of isometamidium in the sera of cattle challenged with drug-resistant Trypanosoma congolense
Whitelaw, D.D.Bell, I.R.Holmes, P.H.Moloo, S.K.Hirumi, H.Urquhart, G.M.Murray, M.[Isometamidium chloride prophylaxis against Trypanosoma congolense challenge and the development of immune responses in Boran cattle]Isometamidium chloride prophylaxis against Trypanosoma congolense challenge and the development of immune responses in Boran cattle
Macaskill, J.A.Holmes, P.H.Whitelaw, D.D.Jennings, F.W.Urquhart, G.M.[Immune mechanisms in C57B1 mice genetically resistant to Trypanosoma congolense infection. 2. Aspects of the humoral response]Immune mechanisms in C57B1 mice genetically resistant to Trypanosoma congolense infection. 2. Aspects of the humoral response
Peregrine, A.S.Ogunyemi, O.Whitelaw, D.D.Holmes, P.H.Moloo, S.K.Hirumi, H.Urquhart, G.M.Murray, M.[Factors influencing the duration of isometamidium chloride (Samorin) prophylaxis against experimental challenge with metacyclic forms of Trypanosoma congolense]Factors influencing the duration of isometamidium chloride (Samorin) prophylaxis against experimental challenge with metacyclic forms of Trypanosoma congolense
Sutherland, I.A.Codjia, V.Moloo, S.K.Holmes, P.H.Peregrine, A.S.[Therapeutic activity of isometamidium chloride in Boran cattle against a clone of Trypanosoma congolense with a low level of drug resistance]Therapeutic activity of isometamidium chloride in Boran cattle against a clone of Trypanosoma congolense with a low level of drug resistance
Sutherland, I.A.Peregrine, A.S.Lonsdale-Eccles, J.D.Holmes, P.H.[Reduced accumulation of isometamidum by drug resistant Trypanosoma congolense]Reduced accumulation of isometamidum by drug resistant Trypanosoma congolense

Two groups of five Boran (Bos indicus) cattle were infected with one of two populations of Trypanosoma congolense; one drug-sensitive (IL1180), and one drug-resistant (IL3330). The animals were then treated intramuscularly with homidium bromide at a dose rate of 1.0 mg kg - bodyweight 7 days afte...


Murilla, G.A.Peregrine, A.S.Ndung'u, J.M.Holmes, P.H.Eisler, M.C.[The effects of drug-sensitive and drug-resistant Trypanosoma congolense infections on the pharmacokinetics of homidium in Boran cattle]The effects of drug-sensitive and drug-resistant Trypanosoma congolense infections on the pharmacokinetics of homidium in Boran cattle

This study has indicated that differences in susceptiblity to Trypanosoma congolense infection exist among the 3 main breeds of goats in Uganda namely, Kigezi, Mubende and small East African (SEA). The Kigezi goats appeared to be the most susceptibe suffering more severe anaemia, greater retardat...


Katunguka-Rwakishaya, E.Murray, M.Holmes, P.H.[Susceptibility of three breeds of Ugandan goats to experimental infection with Trypanosoma congolense]Susceptibility of three breeds of Ugandan goats to experimental infection with Trypanosoma congolense

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