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Journal Article 2006-02-28

Autor: Graham, S.P. Pelle, Roger Honda, Y. Mwangi, D.M. Tonukari, N.J. Yamage, M. Glew, E.J. Villiers, Etienne P. de

East Coast fever, caused by the tick-borne intracellular apicomplexan parasite Theileria parva, is a highly fatal lymphoproliferative disease of cattle. The pathogenic schizont-induced lymphocyte transformation is a unique cancer-like condition that is reversible with parasite removal. Schizont-i...

Enlace original: https://cgspace.cgiar.org/handle/10568/1406

Investigación en Agricultura
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Graham, S.P. ,  Pelle, Roger ,  Honda, Y. ,  Mwangi, D.M. ,  Tonukari, N.J. ,  Yamage, M. ,  Glew, E.J. ,  Villiers, Etienne P. de ,  [Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes] ,  Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes
Journal Article 2007-02-09

Autor: Graham, S.P. Honda, Y. Pelle, Roger Mwangi, D.M. Glew, E.J. Villiers, Etienne P. de Shah, Tushaar Bishop, Richard P. Bruggen, P. van der Nene, Vishvanath Taracha, E.L.N.

Immunity against the bovine protozoan parasite Theileria parva has previously been shown to be mediated through lysis of parasite-infected cells by MHC class I restricted CD8+ cytotoxic T lymphocytes. It is hypothesized that identification of CTL target schizont antigens will aid the development ...

Enlace original: https://cgspace.cgiar.org/handle/10568/1394

Investigación en Agricultura
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Graham, S.P. ,  Honda, Y. ,  Pelle, Roger ,  Mwangi, D.M. ,  Glew, E.J. ,  Villiers, Etienne P. de ,  Shah, Tushaar ,  Bishop, Richard P. ,  Bruggen, P. van der ,  Nene, Vishvanath ,  Taracha, E.L.N. ,  [A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology] ,  A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology
Journal Article 2002

Autor: Chen WenXi Nemoto, T. Kobayashi, T. Saito, T. Kasuya, E. Honda, Y.

A method of recording the fetal electrocardiogram (ECG) and heart rate (HR) is described. An abdominal lead and a thoracic lead were used to measure the fetal ECG and maternal ECG, respectively. The maternal component in the abdominal lead measurement was estimated by a digital adaptive filter ...

Enlace original: https://cgspace.cgiar.org/handle/10568/30078

Investigación en Agricultura
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Chen WenXi ,  Nemoto, T. ,  Kobayashi, T. ,  Saito, T. ,  Kasuya, E. ,  Honda, Y. ,  [ECG and heart rate determination in fetal cattle using a digital signal processing method] ,  ECG and heart rate determination in fetal cattle using a digital signal processing method
Journal Article 1998

Autor: Honda, Y. Waithaka, M.M. Taracha, E.L.N. Duchateau, L. Musoke, A.J. McKeever, Declan J.

To evaluate vaccinia virus as a delivery system for recombinant antigen in cattle, calves were immunized with a recombinant vaccinia virus (rVV) expressing the sporozoite surface antigen (p67) of Theileria parva (V-67) combined with those expressing bovine IL-4 (V-IL4) or IL-2 (V-IL2). The anti-p...

Enlace original: https://cgspace.cgiar.org/handle/10568/29820

Investigación en Agricultura
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Honda, Y. ,  Waithaka, M.M. ,  Taracha, E.L.N. ,  Duchateau, L. ,  Musoke, A.J. ,  McKeever, Declan J. ,  [Delivery of the Theileria parva p67 antigen to cattle using recombinant vaccinia virus: IL-2 enhances protection] ,  Delivery of the Theileria parva p67 antigen to cattle using recombinant vaccinia virus: IL-2 enhances protection
Journal Article 2009-03-15

Autor: Graham, S.P. Pelle, Roger Villiers, Etienne P. de Yamage, M. Mwangi, D.M. Honda, Y. Ellis, S.A. MacHugh, Niall D. Morrison, W. Ivan Taracha, E.L.N.

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated through the destruction of parasite infected lymphocytes by MHC class I restricted CD8+ CTL. Six parasite proteins targeted by CTL from T. parva immune cattle have been identified and raised...

Enlace original: https://cgspace.cgiar.org/handle/10568/32

Investigación en Agricultura
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Graham, S.P. ,  Pelle, Roger ,  Villiers, Etienne P. de ,  Yamage, M. ,  Mwangi, D.M. ,  Honda, Y. ,  Ellis, S.A. ,  MacHugh, Niall D. ,  Morrison, W. Ivan ,  Taracha, E.L.N. ,  [Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva] ,  Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva
Journal Article 2011-04-15

Autor: Mwangi, D.M. Honda, Y. Graham, S.P. Pelle, Roger Taracha, E.L.N. Gachanja, J. Nyanjui, J.K. Bray, J. Palmer, G.H. Brown, W.C. Mwangi, W.

Theileria parva antigens recognized by cytotoxic T lymphocytes (CTLs) are prime vaccine candidates against East Coast Fever in cattle. A strategy for enhancing induction of parasite-specific T cell responses by increasing recruitment and activation of dendritic cells (DCs) at the immunization sit...

Enlace original: https://cgspace.cgiar.org/handle/10568/3074

Investigación en Agricultura
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Mwangi, D.M. ,  Honda, Y. ,  Graham, S.P. ,  Pelle, Roger ,  Taracha, E.L.N. ,  Gachanja, J. ,  Nyanjui, J.K. ,  Bray, J. ,  Palmer, G.H. ,  Brown, W.C. ,  Mwangi, W. ,  [Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses] ,  Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses
Journal Article 1998

Autor: Honda, Y. Matsubara, Y. Morzaria, S.P. McKeever, Declan J.

Theileria parva is the causal agent of East Coast fever (ECF), a fatal disease of cattle characterized by pyrexia, transient lymphadenopathy and panleukopenia. We have evaluated monoclonal antibodies (mAb) against three distinct antigens (p67, PIM and p32) of the parasite as immunohistological re...

Enlace original: https://cgspace.cgiar.org/handle/10568/33247

Investigación en Agricultura
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Honda, Y. ,  Matsubara, Y. ,  Morzaria, S.P. ,  McKeever, Declan J. ,  [Immunohistochemical detection of parasite antigens in Theileria parva-infected bovine lymphocytes] ,  Immunohistochemical detection of parasite antigens in Theileria parva-infected bovine lymphocytes
Journal Article 2008-02-15

Autor: Graham, S.P. Pelle, Roger Yamage, M. Mwangi, D.M. Honda, Y. Mwakubambanya, R.S. Villiers, Etienne P. de Abuya, E. Awino, Elias Gachanja, J. Mbwika, F. Muthiani, A.M. Muriuki, C. Nyanjui, J.K.

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated by CD8 T cells. Six antigens targeted by CD8 T cells from T. parva-immune cattle of different major histocompatibility complex (MHC) genotypes have been identified, raising the prospect of d...

Enlace original: https://cgspace.cgiar.org/handle/10568/1480

Investigación en Agricultura
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Graham, S.P. ,  Pelle, Roger ,  Yamage, M. ,  Mwangi, D.M. ,  Honda, Y. ,  Mwakubambanya, R.S. ,  Villiers, Etienne P. de ,  Abuya, E. ,  Awino, Elias ,  Gachanja, J. ,  Mbwika, F. ,  Muthiani, A.M. ,  Muriuki, C. ,  Nyanjui, J.K. ,  [Characterization of the fine specificity of Bovine CD8 T-Cell responses to defined antigens from the protozoan parasite Theileria parva] ,  Characterization of the fine specificity of Bovine CD8 T-Cell responses to defined antigens from the protozoan parasite Theileria parva

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