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Journal Article 1998

Autor: Honda, Y. Waithaka, M.M. Taracha, E.L.N. Duchateau, L. Musoke, A.J. McKeever, Declan J.

To evaluate vaccinia virus as a delivery system for recombinant antigen in cattle, calves were immunized with a recombinant vaccinia virus (rVV) expressing the sporozoite surface antigen (p67) of Theileria parva (V-67) combined with those expressing bovine IL-4 (V-IL4) or IL-2 (V-IL2). The anti-p...

Enlace original: https://cgspace.cgiar.org/handle/10568/29820

Investigación en Agricultura
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Honda, Y. ,  Waithaka, M.M. ,  Taracha, E.L.N. ,  Duchateau, L. ,  Musoke, A.J. ,  McKeever, Declan J. ,  [Delivery of the Theileria parva p67 antigen to cattle using recombinant vaccinia virus: IL-2 enhances protection] ,  Delivery of the Theileria parva p67 antigen to cattle using recombinant vaccinia virus: IL-2 enhances protection
Journal Article 2009-03-15

Autor: Graham, S.P. Pelle, Roger Villiers, Etienne P. de Yamage, M. Mwangi, D.M. Honda, Y. Ellis, S.A. MacHugh, Niall D. Morrison, W. Ivan Taracha, E.L.N.

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated through the destruction of parasite infected lymphocytes by MHC class I restricted CD8+ CTL. Six parasite proteins targeted by CTL from T. parva immune cattle have been identified and raised...

Enlace original: https://cgspace.cgiar.org/handle/10568/32

Investigación en Agricultura
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Graham, S.P. ,  Pelle, Roger ,  Villiers, Etienne P. de ,  Yamage, M. ,  Mwangi, D.M. ,  Honda, Y. ,  Ellis, S.A. ,  MacHugh, Niall D. ,  Morrison, W. Ivan ,  Taracha, E.L.N. ,  [Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva] ,  Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva
Journal Article 1998

Autor: Honda, Y. Matsubara, Y. Morzaria, S.P. McKeever, Declan J.

Theileria parva is the causal agent of East Coast fever (ECF), a fatal disease of cattle characterized by pyrexia, transient lymphadenopathy and panleukopenia. We have evaluated monoclonal antibodies (mAb) against three distinct antigens (p67, PIM and p32) of the parasite as immunohistological re...

Enlace original: https://cgspace.cgiar.org/handle/10568/33247

Investigación en Agricultura
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Honda, Y. ,  Matsubara, Y. ,  Morzaria, S.P. ,  McKeever, Declan J. ,  [Immunohistochemical detection of parasite antigens in Theileria parva-infected bovine lymphocytes] ,  Immunohistochemical detection of parasite antigens in Theileria parva-infected bovine lymphocytes
Conference Paper 2006

Autor: Mwangi, D.M. Graham, S.P. Pelle, Roger Honda, Y. Tonukari, N.J. Yamage, I.M. Glew, E.J. Villiers, Etienne P. de Shah, Tushaar Bishop, Richard P. Abuya, E. Awino, Elias Gachanja, J. Luyai, A.E. Mbwika, F. Muthiani, A.M. Ndegwa, D.M. Njahira, Moses N. Nyanjui, J.K. Onono, F.O. Osaso, J. Saya, R.M. Wildmann, C. Fraser, C.M. Maudlin, I. Gardner, M.J. Morzaria, S.P. Loosmore, S. Gilbert, S.C. Audonnet, J.C. Bruggen, P. van der Nene, Vishvanath Taracha, E.L.N.

Theileria parva, a tick-borne api-complexan protozoan parasite, causes East Coast fever (ECF) in cattle. Control of the disease by improved vaccination is believed to provide a sustainable solution. Class I MHC-restricted CD8+ cytotoxic T lymphocytes (CTL) directed at schizontinfected cells const...

Enlace original: https://cgspace.cgiar.org/handle/10568/50513

Investigación en Agricultura
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Mwangi, D.M. ,  Graham, S.P. ,  Pelle, Roger ,  Honda, Y. ,  Tonukari, N.J. ,  Yamage, I.M. ,  Glew, E.J. ,  Villiers, Etienne P. de ,  Shah, Tushaar ,  Bishop, Richard P. ,  Abuya, E. ,  Awino, Elias ,  Gachanja, J. ,  Luyai, A.E. ,  Mbwika, F. ,  Muthiani, A.M. ,  Ndegwa, D.M. ,  Njahira, Moses N. ,  Nyanjui, J.K. ,  Onono, F.O. ,  Osaso, J. ,  Saya, R.M. ,  Wildmann, C. ,  Fraser, C.M. ,  Maudlin, I. ,  Gardner, M.J. ,  Morzaria, S.P. ,  Loosmore, S. ,  Gilbert, S.C. ,  Audonnet, J.C. ,  Bruggen, P. van der ,  Nene, Vishvanath ,  Taracha, E.L.N. ,  [Exploiting host immunity and parasite genomics to develop a robust sub-unit vaccine against East Coast fever in cattle - Where are we?] ,  Exploiting host immunity and parasite genomics to develop a robust sub-unit vaccine against East Coast fever in cattle - Where are we?
Journal Article 2008-02-15

Autor: Graham, S.P. Pelle, Roger Yamage, M. Mwangi, D.M. Honda, Y. Mwakubambanya, R.S. Villiers, Etienne P. de Abuya, E. Awino, Elias Gachanja, J. Mbwika, F. Muthiani, A.M. Muriuki, C. Nyanjui, J.K.

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated by CD8 T cells. Six antigens targeted by CD8 T cells from T. parva-immune cattle of different major histocompatibility complex (MHC) genotypes have been identified, raising the prospect of d...

Enlace original: https://cgspace.cgiar.org/handle/10568/1480

Investigación en Agricultura
Enlace permanente
Graham, S.P. ,  Pelle, Roger ,  Yamage, M. ,  Mwangi, D.M. ,  Honda, Y. ,  Mwakubambanya, R.S. ,  Villiers, Etienne P. de ,  Abuya, E. ,  Awino, Elias ,  Gachanja, J. ,  Mbwika, F. ,  Muthiani, A.M. ,  Muriuki, C. ,  Nyanjui, J.K. ,  [Characterization of the fine specificity of Bovine CD8 T-Cell responses to defined antigens from the protozoan parasite Theileria parva] ,  Characterization of the fine specificity of Bovine CD8 T-Cell responses to defined antigens from the protozoan parasite Theileria parva

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