Descubre y comparte nuestro conocimiento público

Se han encontrado 4 recursos

Resultados de búsqueda

To optimize designs to implement marker-assisted introgression programs aiming to introgress three unlinked quantitative trait loci (QTL), the present paper studies different alternatives versus a traditional backcross or intercross phase. Four alternative backcross strategies appear to be more a...


Koudande, O.D.Iraqi, F.A.Thomson, P.C.Teale, A.J.Arendonk, Johan A.M. van[Strategies to optimize marker-assisted introgression of multiple unlinked QTL]Strategies to optimize marker-assisted introgression of multiple unlinked QTL

We developed an F(11) AIL population from an F(1) cross of A/J (susceptible) and C57BL/6J (resistant) mouse strains. One thousand F(11) mice were challenged with P.c. chabaudi 54X, and 340 mice selected from the phenotypic extremes for susceptibility and resistance were genotyped for microsatel...


Hernández Valladares, M.Naessens, JanGibson, John P.Musoke, A.J.Nagda, S.M.Rihet, P.Ole-MoiYoi, O.K.Iraqi, F.A.[Confirmation and dissection of QTL controlling resistance to malaria in mice]Confirmation and dissection of QTL controlling resistance to malaria in mice

A marker-assisted introgression (MAI) experiment was conducted to use genetic markers to transfer each of the three trypanotolerance QTL from a donor mouse strain, C57BL/6, into a recipient mouse strain, A/J. We used a backcross strategy that consisted of selecting two lines, each carrying two of...


Koudande, O.D.Arendonk, Johan A.M. vanIraqi, F.A.[Marker-assisted introgression of trypanotolerance QTL in mice]Marker-assisted introgression of trypanotolerance QTL in mice

The tumor necrosis factor (TNF) locus comprises the tandemly arranged genes coding for Tnfa (cachectin)and Tnfb (lymphotoxin-alpha) (Semon et al. 1987). In mice, the TNF locus is located on chromosome 17 (MMU17) in the major histocompatibility complex (MHC)region. Tnfa and soluble lymphotoxin alp...


Iraqi, F.A.Teale, A.J.[Polymorphisms in the TNFa but not in TNFb microsatellite and correlation with trypanosomiasis in mice]Polymorphisms in the TNFa but not in TNFb microsatellite and correlation with trypanosomiasis in mice

Selecciona los documentos para visualizarlos

Nombre del archivo Ver recurso