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Wambugu, J.Kanguha, E.Hanotte, Olivier H.Davis, S.Taylor, J.Skow, L.Teale, A.J.Iraqi, F.A.[Identification of a polymorphic dinucleotide repeat on a bovine TNF-alpha containing BAC clone]Identification of a polymorphic dinucleotide repeat on a bovine TNF-alpha containing BAC clone

Susceptible A/J and more resistant C57BL/6J mice were infected with Plasmodium chabaudi chabaudi 54X, P.c. chabaudi AS and Plasmodium chabaudi adami 408XZ. As expected, most C57BL/6J mice survived the infections with the different isolates. But in contrast to previous observations, not all A/J ...


Hernández Valladares, M.Naessens, JanNagda, S.M.Musoke, A.J.Rihet, P.Ole-MoiYoi, O.K.Iraqi, F.A.[Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi]Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi

An endogenous virus, denoted evA, is present at high frequency in all brown egg layer lines. Using inverse polymerase chain reaction (PCR) based on the viral LTR regions, products were obtained containing cellular sequences 5' and 3' to the viral insertion point. PCR of chicken genomic DNA was ca...


Nave, A.Iraqi, F.A.Khatib, H.Soller, M.[A PCR - based test for the presence of endogenous virus gene evA in chickens]A PCR - based test for the presence of endogenous virus gene evA in chickens

The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background a...


Churchill, G.A.Airey, D.C.Allayee, H.Angel, J.M.Attie, A.D.Beatty, J.Beavis, W.D.Belknap, J.K.Bennett, B.Berrettini, W.Bleich, A.Bogue, M.Broman, K.W.Buck, K.J.Buckler, E.Burmeister, M.Chesler, E.J.Cheverud, J.M.Clapcote, S.Cook, M.N.Cox, R.D.Crabbe, J.C.Crusio, W.E.Darvasi, A.Deschepper, C.F.Doerge, R.W.Farber, C.R.Forejt, J.Gaile, D.Garlow, S.J.Geiger, H.Gershenfeld, H.Gordon, T.Gu, J.Gu, W.Haan, G. deHayes, N.L.Heller, C.Himmelbauer, H.Hitzemann, R.Hunter, K.Hsu, H.-C.Iraqi, F.A.Ivandic, B.Jacob, H.J.Jansen, R.C.Jepsen, K.J.Johnson, D.K.Johnson, T.E.Kempermann, G.Kendziorski, C.Kotb, M.Kooy, R.F.Llamas, B.Lammert, F.Lassalle, J.M.Lowenstein, P.R.Lu, L.Lusis, A.Manly, K.F.Marcucio, R.Matthews, D.Medrano, J.F.Miller, D.R.Mittleman, G.Mock, B.A.Mogil, J.S.Montagutelli, X.Morahan, G.Morris, D.G.Mott, R.Nadeau, J.H.Nagase, H.Nowakowski, R.S.O'Hara B.F.Osadchuk, A.V.Page, G.P.Paigen, B.Paigen, K.Palmer, A.A.Pan, H.J.Peltonen-Palotie, L.Peirce, J.Pomp, D.Pravenec, M.Prows, D.R.Qi, Z.Reeves, R.H.Roder, J.Rosen, G.D.Schadt, E.E.Schalkwyk, L.C.Seltzer, Z.Shimomura, K.Shou, S.Sillanpaa, M.J.Siracusa, L.D.Snoeck, H.W.Spearow, J.L.Svenson, K.Tarantino, L.M.Threadgill, D.Toth, L.A.Valdar, W.Pardo-Manuel de Villena, F.Warden, C.Whatley, S.Williams, R.W.Wiltshire, T.Yi, N.Zhang, D.Zhang, M.Zou, F.[The Collaborative Cross, a community resource for the genetic analysis of complex traits]The Collaborative Cross, a community resource for the genetic analysis of complex traits

Breeds of cattle, sheep and goats have been identified which are genetically resistant and/or tolerant to gastro-intestinal nematode parasites. Mapping and cloning of resistant genes will facilitate Development of new breeds of livestock, which combine this important disease resistance trait with...


Iraqi, F.A.Menge, D.Gibson, P.J.Baker, R.L.Wakelin, D.Behnke, J.M.Lowe, A.Teale, A.J.Wakelin, D.[Mapping chromosomal regions controlling resistance to gastro-intestinal worms in mice. Poster presentation]Mapping chromosomal regions controlling resistance to gastro-intestinal worms in mice. Poster presentation
Menge, D.Behnke, J.Lowe, A.Gibson, John P.Baker, L.Wakelin, D.Iraqi, F.A.[Mapping of QTL influencing immunological responses to gastrointestinal nematode infection in mice. Abstract]Mapping of QTL influencing immunological responses to gastrointestinal nematode infection in mice. Abstract
Hernández Valladares, M.Ole-MoiYoi, O.K.Iraqi, F.A.[Mapping of new quantitative trait loci (QTL) resistance to malaria in mice by a comparative mapping approach of human chromosome 5 q31 - q33. Abstract]Mapping of new quantitative trait loci (QTL) resistance to malaria in mice by a comparative mapping approach of human chromosome 5 q31 - q33. Abstract
Behnke, J.Iraqi, F.A.Menge, D.Lowe, A.Teale, A.J.Gibson, P.J.Baker, R.L.Wakelin, D.[Mapping chromosomal regions controlling resistance to gastro-intestinal worms in mice]Mapping chromosomal regions controlling resistance to gastro-intestinal worms in mice

Genome-wide quantitative trait locus (QTL) mapping was used to evaluate the genetic basis of resistance to Helgmosomides polygyrus in an F2 cross of SWR and CBA mouse strains that are resistant and susceptible, respectively, to infection. 25 significant QTL affecting at least one of the resistanc...


Menge, D.M.Behnke, J.M.Iraqi, F.A.Lowe, A.Teale, A.J.Gibson, John P.Wakelin, D.Baker, R.L.[Quantitative trait loci for resistance to gastro-intestinal nematode infections in mice]Quantitative trait loci for resistance to gastro-intestinal nematode infections in mice

C57BL/6J mice are relatively resistant to trypanosomosis compared to BALB/c or A/J mice. Bloodstream trypanosomes are partly dependent on the host for lipid supply and the plasma lipid levels differ between resistant and susceptible mice. Furthermore, genes controlling plasma lipid levels are dif...


Hassan, M.Agaba, MorrisBulimo, WallaceNoyes, H.Brass, A.Hinsley, T.Iraqi, F.A.Kemp, Stephen J.[Role of plasma lipids in the susceptibility of laboratory mice to trypanosomosis]Role of plasma lipids in the susceptibility of laboratory mice to trypanosomosis

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