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Journal Article 2001

Autor: Falconi, C.A. Omamo, S.W. D'Ieteren, G.D.M. Iraqi, F.A.

This paper undertakes an ex ante economic analysis of research on how resistance to trypanosomosis - a dominant livestock disease in Africa - can be maintained and enhanced while retaining and reinforcing characteristics of economic importance to farmers, and on how 'trypanotolerance' can be impa...

Enlace original: https://cgspace.cgiar.org/handle/10568/28079

Investigación en Agricultura
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Falconi, C.A. ,  Omamo, S.W. ,  D'Ieteren, G.D.M. ,  Iraqi, F.A. ,  [An ex ante economic and policy analysis of research on genetic resistance to livestock disease: Trypanosomiasis in Africa] ,  An ex ante economic and policy analysis of research on genetic resistance to livestock disease: Trypanosomiasis in Africa
Journal Article 2004

Autor: Hernández Valladares, M. Rihet, P. Ole-MoiYoi, O.K. Iraqi, F.A.

A number of linkage studies in human populations have identified a locus ( pfbi) on Chromosome 5q31-q33 controlling Plasmodiun falciparum blood infection levels. This region contains numerous candidate genes encoding immunological molecules such as cytokines, growth factors and growth-factor rec...

Enlace original: https://cgspace.cgiar.org/handle/10568/32938

Investigación en Agricultura
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Hernández Valladares, M. ,  Rihet, P. ,  Ole-MoiYoi, O.K. ,  Iraqi, F.A. ,  [Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33] ,  Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33
Journal Article 2007

Autor: Hernández Valladares, M. Naessens, Jan Iraqi, F.A.

Gene-knockout mice have been extensively used in the study of several malaria-induced pathologies. Some investigators believe that the deficient, infected mice mimic disease aspects produced in the absence of the target gene, but others believe that the deficient mice models mainly explain the ef...

Enlace original: https://cgspace.cgiar.org/handle/10568/33188

Investigación en Agricultura
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Hernández Valladares, M. ,  Naessens, Jan ,  Iraqi, F.A. ,  [Gene-knockout mice in malaria research: Useful or misleading?] ,  Gene-knockout mice in malaria research: Useful or misleading?
Journal Article 2005

Autor: Hernández Valladares, M. Naessens, Jan Iraqi, F.A.

Murine models have proved to be excellent tools in the support of studies of the human genetic bases of malaria resistance and have enabled the mapping of 12 resistance loci, eight of them controlling parasitic levels and four controlling cerebral malaria. Further studies using this method have i...

Enlace original: https://cgspace.cgiar.org/handle/10568/33187

Investigación en Agricultura
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Hernández Valladares, M. ,  Naessens, Jan ,  Iraqi, F.A. ,  [Genetic resistance to malaria in mouse models] ,  Genetic resistance to malaria in mouse models
Journal Article 2003

Autor: Behnke, J.M. Iraqi, F.A. Menge, D. Baker, R.L. Gibson, John P. Wakelin, D.

The host-protective immune response to infection with gastrointestinal (GI) nematodes involves a range of interacting processes that begin with recognition of the parasite's antigens and culminate in an inflammatory reaction in the intestinal mucosa. Precisely which immune effectors are responsib...

Enlace original: https://cgspace.cgiar.org/handle/10568/33007

Investigación en Agricultura
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Behnke, J.M. ,  Iraqi, F.A. ,  Menge, D. ,  Baker, R.L. ,  Gibson, John P. ,  Wakelin, D. ,  [Chasing the genes that control resistance to gastrointestinal nematodes] ,  Chasing the genes that control resistance to gastrointestinal nematodes
Journal Article 2006

Autor: Behnke, J.M. Mugambi, J.M.M. Clifford, S. Iraqi, F.A. Baker, R.L. Gibson, John P. Wakelin, D.

Since the publication of the mouse genome, attention has focused on the strains that were selected for sequencing. In this paper we report the results of experiments that characterized the response to infection with the murine gastrointestinal nematode Heligmosomoides polygyrus of eight new strai...

Enlace original: https://cgspace.cgiar.org/handle/10568/33090

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Behnke, J.M. ,  Mugambi, J.M.M. ,  Clifford, S. ,  Iraqi, F.A. ,  Baker, R.L. ,  Gibson, John P. ,  Wakelin, D. ,  [Genetic variation in resistance to repeated infections with Heligmosomoides polygyrus bakeri, in inbred mouse strains selected for the mouse genome project] ,  Genetic variation in resistance to repeated infections with Heligmosomoides polygyrus bakeri, in inbred mouse strains selected for the mouse genome project
Journal Article 2003

Autor: Wang, M. Lemon, W.J. Liu, G. Wang, Y. Iraqi, F.A. Malkinson, A.M. You, M.

In the present study, we used newly developed F11 generation mouse advanced intercross lines (AIL) to fine map Pas1–3 quantitative trait loci (QTL). The (A/J x C57BL/6) F11 AIL mouse population was created by crossing lung tumor-resistant C57BL/6 mice with lung tumor-susceptible A/J mice. By se...

Enlace original: https://cgspace.cgiar.org/handle/10568/32868

Investigación en Agricultura
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Wang, M. ,  Lemon, W.J. ,  Liu, G. ,  Wang, Y. ,  Iraqi, F.A. ,  Malkinson, A.M. ,  You, M. ,  [Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines] ,  Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines
Journal Article 2003

Autor: Iraqi, F.A. Behnke, J.M. Menge, D.M. Lowe, A.M. Teale, A.J. Gibson, John P. Baker, L.R. Wakelin, D.R.

Quantitative trait loci (QTL) associated with resistance to an intestinal worm in a well-defined murine model are described. These have been identified in an F(2) population derived from resistant (SWR) and susceptible (CBA) parental mouse strains infected with the gastro-intestinal nematode par...

Enlace original: https://cgspace.cgiar.org/handle/10568/29203

Investigación en Agricultura
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Iraqi, F.A. ,  Behnke, J.M. ,  Menge, D.M. ,  Lowe, A.M. ,  Teale, A.J. ,  Gibson, John P. ,  Baker, L.R. ,  Wakelin, D.R. ,  [Chromosomal regions controlling resistance to gastro-intestinal nematode infections in mice] ,  Chromosomal regions controlling resistance to gastro-intestinal nematode infections in mice
Journal Article 2004

Autor: Hernández Valladares, M. Naessens, Jan Gibson, John P. Musoke, A.J. Nagda, S.M. Rihet, P. Ole-MoiYoi, O.K. Iraqi, F.A.

We developed an F(11) AIL population from an F(1) cross of A/J (susceptible) and C57BL/6J (resistant) mouse strains. One thousand F(11) mice were challenged with P.c. chabaudi 54X, and 340 mice selected from the phenotypic extremes for susceptibility and resistance were genotyped for microsatel...

Enlace original: https://cgspace.cgiar.org/handle/10568/29204

Investigación en Agricultura
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Hernández Valladares, M. ,  Naessens, Jan ,  Gibson, John P. ,  Musoke, A.J. ,  Nagda, S.M. ,  Rihet, P. ,  Ole-MoiYoi, O.K. ,  Iraqi, F.A. ,  [Confirmation and dissection of QTL controlling resistance to malaria in mice] ,  Confirmation and dissection of QTL controlling resistance to malaria in mice
Journal Article 2004

Autor: Hernández Valladares, M. Naessens, Jan Nagda, S.M. Musoke, A.J. Rihet, P. Ole-MoiYoi, O.K. Iraqi, F.A.

Susceptible A/J and more resistant C57BL/6J mice were infected with Plasmodium chabaudi chabaudi 54X, P.c. chabaudi AS and Plasmodium chabaudi adami 408XZ. As expected, most C57BL/6J mice survived the infections with the different isolates. But in contrast to previous observations, not all A/J ...

Enlace original: https://cgspace.cgiar.org/handle/10568/32918

Investigación en Agricultura
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Hernández Valladares, M. ,  Naessens, Jan ,  Nagda, S.M. ,  Musoke, A.J. ,  Rihet, P. ,  Ole-MoiYoi, O.K. ,  Iraqi, F.A. ,  [Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi] ,  Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi

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