Heterogeneity between centers in multicenter trials with time to event outcome can be modeled by the frailty proportional hazards model. The majority of the different approaches that have been used to fit frailty models assume either the gamma or the lognormal frailty density and are based on sim...
Enlace original:
https://cgspace.cgiar.org/handle/10568/28432
Duchateau, L.
,
Janssen, P.
,
Lindsey, P.
,
Legrand, C.
,
Nguti, R.
,
Sylvester-Bradley, Rosemary
,
[The shared frailty model and the power for heterogeneity tests in multicenter trials]
,
The shared frailty model and the power for heterogeneity tests in multicenter trials
