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Mycoplasma mycoides subsp. mycoides is the etiologic agent of contagious bovine pleuropneumonia. We report here the complete genome sequence of the strain T1/44, which is widely used as a live vaccine in Africa.


Gourgues, G.Barre, A.Beaudoing, E.Weber, J.Magdelenat, G.Barbe, V.Schieck, Elise G.Jores, JoergVashee, S.Blanchard, AlainLartigue, C.Sirand-Pugnet, P.[Complete genome sequence of Mycoplasma mycoides subsp. mycoides T1/44, a vaccine strain against contagious bovine pleuropneumonia]Complete genome sequence of Mycoplasma mycoides subsp. mycoides T1/44, a vaccine strain against contagious bovine pleuropneumonia

capacity and infrastructure of government services for disease identification and control are often limited. In the absence of systematic surveillance systems for animal diseases, the information on pathogens affecting livestock has been filled by targeted surveys conducted in certain locations a...


Alonso, SilviaToye, Philip G.Jores, JoergWakhungu, Judi W.Msalya, G.Grace, DeliaUnger, Fred[The known and the unknowns: A multipathogen survey to identify diseases in cattle herds in Tanzania]The known and the unknowns: A multipathogen survey to identify diseases in cattle herds in Tanzania

Cattle diseases remain a major constraint to increasing dairy productivity in Tanzania, by killing or keeping them sick and under-producing. Recent studies report overall mortality between 12 and 14 % in smallholder dairy cattle across different regions of Tanzania. Many of these diseases can als...


Alonso, SilviaUnger, FredToye, Philip G.Jores, JoergWakhungu, Judi W.Msalya, G.Grace, Delia[Cattle diseases in dairy herds in Tanzania: Farmers’ view and laboratory confirmation]Cattle diseases in dairy herds in Tanzania: Farmers’ view and laboratory confirmation

Mycoplasma mycoides subsp. mycoides SC is the pathogenic agent of contagious bovine pleuropneumonia (CBPP), the most important disease of cattle in Africa causing significant economic losses. The re-emergence of CBPP in Europe in the 1980s and 1990s illustrates that it is still a threat also to c...


Schnee, C.Heller, M.Jores, JoergTomaso, H.Neubauer, H.[Assessment of a novel multiplex real-time PCR assay for the detection of the CBPP agent Mycoplasma mycoides subsp. mycoides SC through experimental infection in cattle]Assessment of a novel multiplex real-time PCR assay for the detection of the CBPP agent Mycoplasma mycoides subsp. mycoides SC through experimental infection in cattle
Schubert, E.Sachse, K.Jores, JoergHeller, M.[Serological testing of cattle experimentally infected with Mycoplasma mycoides subsp. mycoides Small Colony using four different tests reveals a variety of seroconversion patterns]Serological testing of cattle experimentally infected with Mycoplasma mycoides subsp. mycoides Small Colony using four different tests reveals a variety of seroconversion patterns
Autor: Jores, Joerg

Contagious Bovine Pleuropneumonia (CBPP) is a highly contagious disease that affects cattle throughout most of sub Saharan Africa. It is one of the most serious livestock diseases with greatest impacts in pastoralist areas. Up to 15% of infected animals die: milk yields of infected cows drop by u...


Jores, Joerg[Developing a vaccine for a highly contagious cattle disease]Developing a vaccine for a highly contagious cattle disease

Mycoplasma mycoides subsp. mycoides (Mmm) is the causative agent of contagious bovine pleuropneumonia (CBPP), a severe pleuropneumonia in cattle. The abnormal accumulation of pleural fluid, called pleural effusion (PE), is one of the characteristics of this disease. We performed a proteomic analy...


Weldearegay, Yenehiwot BerhanuPich, AndreasSchieck, Elise G.Liljander, Anne M.Gicheru, N.Wesonga, H.O.Thiaucourt, FrancoisKiirika, L.M.Valentin-Weigand, PeterJores, JoergMeens, J.[Proteomic characterization of pleural effusion, a specific host niche of Mycoplasma mycoides subsp. mycoides from cattle with contagious bovine pleuropneumonia (CBPP)]Proteomic characterization of pleural effusion, a specific host niche of Mycoplasma mycoides subsp. mycoides from cattle with contagious bovine pleuropneumonia (CBPP)

The ‘Mycoplasma mycoides cluster’ comprises the ruminant pathogens Mycoplasma mycoides subsp. mycoides the causative agent of contagious bovine pleuropneumonia (CBPP), Mycoplasma capricolum subsp. capripneumoniae the agent of contagious caprine pleuropneumonia (CCPP), Mycoplasma capricolum subsp....


Fischer, A.Shapiro, Barry I.Muriuki, C.Heller, M.Schnee, C.Bongcam-Rudloff, E.Frey, J.Jores, Joerg[The origin of the Mycoplasma mycoides cluster coincides with domestication of ruminants]The origin of the Mycoplasma mycoides cluster coincides with domestication of ruminants

Current contagious bovine pleuropneumonia (CBPP) vaccines are based on live-attenuated strains of Mycoplasma mycoides subsp. mycoides (Mmm). These vaccines have shortcomings in terms of efficacy, duration of immunity and in some cases show severe side effects at the inoculation site; hence the ne...


Pérez Casal, J.Prysliak, T.Maina, T.Wang, Y.Townsend, H.Berverov, E.Nkando, I.Wesonga, H.O.Liljander, Anne M.Jores, JoergNaessens, JanGerdts, V.Potter, A.[Analysis of immune responses to recombinant proteins from strains of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious Bovine pleuropneumonia]Analysis of immune responses to recombinant proteins from strains of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious Bovine pleuropneumonia

Contagious Bovine Pleuropneumonia (CBPP), caused by Mycoplasma mycoides subsp. mycoides, is widespread in sub-Saharan Africa. The current live vaccine T1/44 has limited efficacy and occasionally leads to severe side effects in the animals. A better understanding of the immune responses triggered ...


Sacchini, F.Luciani, M.Salini, R.Scacchia, M.Pini, A.Lelli, R.Naessens, JanPoole, Elizabeth J.Jores, Joerg[Plasma levels of TNF-α, IFN-γ, IL-4 and IL-10 during a course of experimental contagious bovine pleuropneumonia]Plasma levels of TNF-α, IFN-γ, IL-4 and IL-10 during a course of experimental contagious bovine pleuropneumonia

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