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A preliminary search for QTLs in a cattle F2 resource populations segregating for trypanotolerance has revealed three large candidate chromosomal regions (Bta02, Bta05, Bta07). In order to narrow down the position of the trypanotolerant QTLs, we are building comparative chromosomal maps between c...


Nilsson, P.H.Kang'a, S.Rottengatter, K.Suedbeck, U.Iraqui, F.Mwakaya, J.Mwangi, D.Womack, J.E.Goldammer, T.Schwerin, M.Bradley, D.Agaba, MorrisSugimoto, K.Gelhaus, A.Horstmann, R.Teale, A.J.Kemp, Stephen J.Hanotte, Olivier H.[Radiation hybrid maps of candidate trypanotolerance regions in cattle]Radiation hybrid maps of candidate trypanotolerance regions in cattle

An alternative approach for the direct analysis of chromosome regions corresponding to economical traits, based on chromosome microdissection, is described. Large fragment clones isolated with primer pairs designed from chromosome fragment-specific DNA sequences were localized by fluorescence in ...


Goldammer, T.Brunner, R.M.Kang'a, S.Hanotte, Olivier H.Schwerin, M.[Establishment of bovine chromosome region specific high resolution maps using microdissection]Establishment of bovine chromosome region specific high resolution maps using microdissection

The paper first describes interleukin-12 P35 encoding gene and discusses its role. It then looks into PCR conditions and sequencing; genotyping; sequencing; polymorphism frequency; mendelian inheritance; chromosomal location in sheep and cattle of different species.


Schmidt, P.Kuhn, C.Kang'a, S.Hanotte, Olivier H.Vanselow, J.Anton, I.Langner, ChSchwerin, M.[Interleukin - 12 p35 encoding gene of cattle and sheep harbours a polymorphic T stretch in intron 4]Interleukin - 12 p35 encoding gene of cattle and sheep harbours a polymorphic T stretch in intron 4
Kang'a, S.Nilsson, P.Goldammer, T.Mwakaya, J.Njagi, E.N.M.Schwerin, M.Hanotte, Olivier H.[Construction of a BAC contig at a cattle QTL region controlling resistance to trypanosomosis on BTA7 that is homologous to the murine T1R1 region on MMU17]Construction of a BAC contig at a cattle QTL region controlling resistance to trypanosomosis on BTA7 that is homologous to the murine T1R1 region on MMU17

Trypanosomiasis is one of the most important diseases in African cattle. About 3 million cattle die every year by this disease. However, about 5 percent of the total African cattle have a natural resistance against trypanosomiasis. In a preliminary study markers linked to trypanotolerance have be...


Goldammer, T.Brunner, R.M.Kang'a, S.Hanotte, Olivier H.Schwerin, M.[Generation of a bovine BAC pool for chromosome region BTA7q14-22 correlated to the trait trypanotolerance]Generation of a bovine BAC pool for chromosome region BTA7q14-22 correlated to the trait trypanotolerance

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