Background
The neglected zoonotic diseases (NZD) are an understudied group that are a major cause of illness throughout the developing world. In general, little is known about the prevalence and burden of NZDs in affected communities, particularly in relation to other infectious diseases with whi...
Fèvre, Eric M.
,
Glanville, William A. de
,
Thomas, L.F.
,
Cook, Elizabeth A.J.
,
Kariuki, S.
,
Wamae, C.N.
,
[An integrated study of human and animal infectious disease in the Lake Victoria crescent small-holder crop-livestock production system, Kenya]
,
An integrated study of human and animal infectious disease in the Lake Victoria crescent small-holder crop-livestock production system, Kenya
Rift Valley fever virus (RVFV) is a zoonotic arbovirus affecting livestock and people. This study was conducted in western Kenya where RVFV outbreaks have not previously been reported. The aims were to document the seroprevalence and risk factors for RVFV antibodies in a community-based sample fr...
Cook, Elizabeth A.J.
,
Grossi-Soyster, E.N.
,
Glanville, William A. de
,
Thomas, L.F.
,
Kariuki, S.
,
Bronsvoort, B.M. de C.
,
Wamae, C.N.
,
LaBeaud, A.D.
,
Fèvre, Eric M.
,
[The sero-epidemiology of Rift Valley fever in people in the Lake Victoria Basin of western Kenya]
,
The sero-epidemiology of Rift Valley fever in people in the Lake Victoria Basin of western Kenya
Background
Inadequate facilities and hygiene at slaughterhouses can result in contamination of meat and occupational hazards to workers. The objectives of this study were to assess current conditions in slaughterhouses in western Kenya and the knowledge, and practices of the slaughterhouse worker...
Cook, Elizabeth A.J.
,
Glanville, William A. de
,
Thomas, L.F.
,
Kariuki, S.
,
Bronsvoort, B.M. de C.
,
Fèvre, Eric M.
,
[Working conditions and public health risks in slaughterhouses in western Kenya]
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Working conditions and public health risks in slaughterhouses in western Kenya
There are substantial limitations in our understanding of the distribution of antimicrobial resistance (AMR) in humans and livestock in developing countries. Here, we present the results of an epidemiological study examining patterns of AMR in Escherichia coli isolates circulating in sympatric hu...
Muloi, Dishon
,
Kiiru, J.
,
Ward, M.J.
,
Hassell, James M.
,
Bettridge, Judy M.
,
Robinson, T.P.
,
Bunnik, B.A.D. van
,
Chase-Topping, M.
,
Robertson, G.
,
Pedersen, A.B.
,
Fèvre, Eric M.
,
Woolhouse, Mark E.J.
,
Kang'ethe, Erastus K.
,
Kariuki, S.
,
[Epidemiology of antimicrobial-resistant Escherichia coli carriage in sympatric humans and livestock in a rapidly urbanizing city]
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Epidemiology of antimicrobial-resistant Escherichia coli carriage in sympatric humans and livestock in a rapidly urbanizing city
The neglected tropical diseases (NTDs) are characterized by their tendency to cluster within groups of people, typically the poorest and most marginalized. Despite this, measures of clustering, such as within-group correlation or between-group heterogeneity, are rarely reported from community-bas...
Glanville, William A. de
,
Thomas, Lian F.
,
Cook, Elizabeth A.J.
,
Bronsvoort, B.M. de C.
,
Wardrop, N.
,
Wamae, C.N.
,
Kariuki, S.
,
Fèvre, Eric M.
,
[General contextual effects on neglected tropical disease risk in rural Kenya]
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General contextual effects on neglected tropical disease risk in rural Kenya
Alphaviruses, such as chikungunya virus, and flaviviruses, such as dengue virus, are (re)-emerging arboviruses that are endemic in tropical environments. In Africa, arbovirus infections are often undiagnosed and unreported, with febrile illnesses often assumed to be malaria. This cross-sectional ...
Grossi-Soyster, E.N.
,
Cook, Elizabeth A.J.
,
Glanville, William A. de
,
Thomas, L.F.
,
Krystosik, A.R.
,
Lee, J.
,
Wamae, C.N.
,
Kariuki, S.
,
Fèvre, Eric M.
,
LaBeaud, A.D.
,
[Serological and spatial analysis of alphavirus and flavivirus prevalence and risk factors in a rural community in western Kenya]
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Serological and spatial analysis of alphavirus and flavivirus prevalence and risk factors in a rural community in western Kenya
Tularemia is a highly contagious infectious zoonosis caused by the bacterial agent Francisella tularensis. The aim of this study was to investigate the presence of antibodies to Francisella tularensis in febrile patients in northeastern Kenya. During 2014-2015, 730 patients were screened for anti...
Njeru, J.
,
Tomaso, H.
,
Mertens, K.
,
Henning, K.
,
Wareth, G.
,
Heller, R.
,
Kariuki, S.
,
Fèvre, Eric M.
,
Neubauer, H.
,
Pletz, M.W.
,
[Serological evidence of Francisella tularensis in febrile patients seeking treatment at remote hospitals, Northeastern Kenya, 2014-2015]
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Serological evidence of Francisella tularensis in febrile patients seeking treatment at remote hospitals, Northeastern Kenya, 2014-2015
Background
Antimicrobial resistance is one of the great challenges facing global health security in the modern era. Wildlife, particularly those that use urban environments, are an important but understudied component of epidemiology of antimicrobial resistance. We investigated antimicrobial resi...
Hassell, J.M.
,
Ward, M.J.
,
Muloi, D.
,
Bettridge, Judy M.
,
Robinson, T.P.
,
Kariuki, S.
,
Ogendo, A.
,
Kiiru, J.
,
Imboma, T.
,
Kang'ethe, Erastus K.
,
Öghren, E.M.
,
Williams, N.J.
,
Begon, M.
,
Woolhouse, Mark E.J.
,
Fèvre, Eric M.
,
[Clinically relevant antimicrobial resistance at the wildlife–livestock–human interface in Nairobi: An epidemiological study]
,
Clinically relevant antimicrobial resistance at the wildlife–livestock–human interface in Nairobi: An epidemiological study
Land-use change is predicted to act as a driver of zoonotic disease emergence through human exposure to novel microbial diversity, but evidence for the effects of environmental change on microbial communities in vertebrates is lacking. We sample wild birds at 99 wildlife-livestock-human interface...
Hassell, J.M.
,
Ward, M.J.
,
Muloi, D.
,
Bettridge, Judy M.
,
Phan, H.
,
Robinson, T.P.
,
Ogendo, A.
,
Imboma, T.
,
Kiiru, J.
,
Kariuki, S.
,
Begon, M.
,
Kang'ethe, Erastus K.
,
Woolhouse, Mark E.J.
,
Fèvre, Eric M.
,
[Deterministic processes structure bacterial genetic communities across an urban landscape]
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Deterministic processes structure bacterial genetic communities across an urban landscape
The importance of household socio-economic position (SEP) in shaping individual infectious disease risk is increasingly recognised, particularly in low income settings. However, few studies have measured the extent to which this association is consistent for the range of pathogens that are typica...
Glanville, William A. de
,
Thomas, L.F.
,
Cook, Elizabeth A.J.
,
Bronsvoort, B.M. de C.
,
Wamae, N.C.
,
Kariuki, S.
,
Fèvre, Eric M.
,
[Household socio-economic position and individual infectious disease risk in rural Kenya]
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Household socio-economic position and individual infectious disease risk in rural Kenya