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Shompole, S.McElwain, T.F.Jasmer, D.P.Hines, S.A.Katende, J.Musoke, A.J.Rurangirwa, F.R.McGuire, T.C.[Identification of Babesia bigemina infected erythrocyte surface antigens containing epitopes conserved among strains]Identification of Babesia bigemina infected erythrocyte surface antigens containing epitopes conserved among strains

Tick-borne diseases (TBDs) are a major economic constraint to livestock production in sub-Saharan Africa. ILRI is focussing on developing a range of products, such as vaccines, diagnostics and decision support services to underpin improved control programmes against these diseases. We have develo...


Morzaria, S.P.Katende, J.Musoke, A.J.Nene, VishvanathSkilton, Robert A.Bishop, Richard P.[Development of sero-diagnostic and molecular tools for the control of important tick-borne pathogens of cattle in Africa]Development of sero-diagnostic and molecular tools for the control of important tick-borne pathogens of cattle in Africa

Current serological tests for Babesia bigemina use semipurified merozoite antigens derived from infected erythrocytes. One of the major drawbacks of these tests is that antigen quality can vary from batch to batch. Since the quality of the antigen contributes to the sensitivity and specificity of...


Tebele, N.Skilton, Robert A.Katende, J.Wells, C.W.Nene, VishvanathMcElwain, T.F.Morzaria, S.P.Musoke, A.J.[Cloning, characterization and expression of a 200 Kilodalton diagnostic antigen of Babesia bigemina]Cloning, characterization and expression of a 200 Kilodalton diagnostic antigen of Babesia bigemina

A 69-kDa antigen of Trypanosoma congolense induces both IgM and IgG in experimentally infected cattle. Cloning and sequencing of the gene coding for this antigen revealed that it belongs to the heat shock protein 70 family (hsp70) and is homologous to mammalian immunoglobulin binding protein (BiP...


Boulange, A.F.Katende, J.Authié, E.[A heat shock protein 70 of Trypanosoma congolense as a diagnositic antigen]A heat shock protein 70 of Trypanosoma congolense as a diagnositic antigen

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