A 69-kDa immunodominant protein of Trypanosoma congolense was identified as a member of the hsp70 family that is homologous to mammalian BiP. We report here the expression of the gene encoding the T. congolense BiP in a bacterial system. Dot blotting of the truncated recombinant proteins confirme...
Boulange, A.F.
,
Katende, J.
,
Authié, E.
,
[Trypanosoma congolense: Expression of a heat shock protein 70 and initial evaluation as a diagnostic antigen for bovine trypanosomosis]
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Trypanosoma congolense: Expression of a heat shock protein 70 and initial evaluation as a diagnostic antigen for bovine trypanosomosis
Two recombinant vaccines against Theileria parva, based on a near full-length version of the sporozoite surface antigen p67 (p67635), or an 80 amino acid C-terminal section (p67C), were evaluated by exposure of immunized cattle to natural tick challenge in two sites at the Kenya Coast and one i...
Musoke, A.J.
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Rowlands, G.J.
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Nene, Vishvanath
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Nyanjui, J.
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Katende, J.
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Spooner, P.R.
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Mwaura, S.
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Odongo, D.
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Nkonge, C.
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Mbogo, S.
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Bishop, Richard P.
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Morzaria, S.P.
,
[Subunit vaccine based on the p67 major surface protein of Theileria parva sporozoites reduces severity of infection derived from field tick challenge]
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Subunit vaccine based on the p67 major surface protein of Theileria parva sporozoites reduces severity of infection derived from field tick challenge
Mice were immunized with either an isometamidium-human serum albumin (HSA) conjugate or an isometamidium-porcine thyroglobulin conjugate (PTG). Thereafter, monoclonal antibodies (MAbs) IL-A 1001, IL-A 1002, IL-A 1003, 5F7.B7, and 5F7.C9 were generated and selected on the basis that they recognize...
Peregrine, A.S.
,
Eisler, M.C.
,
Katende, J.
,
Flynn, J.N.
,
Gault, E.A.
,
Kinabo, L.D.B.
,
Holmes, P.H.
,
[Generation of monoclonal antibodies to the anti-trypanosomal drug isometamidium]
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Generation of monoclonal antibodies to the anti-trypanosomal drug isometamidium