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Tsetse fly-transmitted trypanosomes (Trypanosoma spp.) cause 'sleeping sickness' in man and have a serious impact on livestock-based agriculture in large areas of Africa. Multigene control of variation in susceptibility to trypanosomiasis is known to occur in mice, where the C57BI/6 (B6) strain i...


Kemp, Stephen J.Iraqi, F.A.Darvasi, A.Soller, M.Teale, A.J.[Localization of genes controlling resistance to trypanosomiasis in mice]Localization of genes controlling resistance to trypanosomiasis in mice

Kemp, Stephen J.Nene, Vishvanath[Biosciences research at the International Livestock Research Institute (ILRI)]Biosciences research at the International Livestock Research Institute (ILRI)
Bensaid, A.M.Naessens, JanKemp, Stephen J.Black, S.J.Shapiro, S.Z.Teale, A.J.[An immunochemical analysis of class I (BoLA) molecules on the surface of bovine cells]An immunochemical analysis of class I (BoLA) molecules on the surface of bovine cells

African trypanosomes are protozoan parasites that cause “sleeping sickness” in humans and a similar disease in livestock. Trypanosomes also infect laboratory mice and three major quantitative trait loci (QTL) that regulate survival time after infection with T. congolense have been identified in t...


Goodhead, I.Archibald, A.L.Amwayi, P.Brass, A.Gibson, John P.Hall, N.Hughes, Monica A.Limo, M.K.H.Iraqi, F.A.Kemp, Stephen J.Noyes, H.A.[A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice]A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice

Some West African Bos taurus cattle breeds such as the N'Dama and a number of West African Shorthorns are resistant to tsetse fly-transmitted trypanosomosis. The trait is termed trypanotolerance, for which changes in packed red cell volume percent (PCV) and growth rate following infection are ge...


Waaij, E.H. van derHanotte, Olivier H.Arendonk, Johan A.M. vanKemp, Stephen J.Kennedy, D.Gibson, John P.Teale, A.J.[Population parameters for traits defining trypanotolerance in an F2 cross of N'Dama and Boran cattle]Population parameters for traits defining trypanotolerance in an F2 cross of N'Dama and Boran cattle
Morrison, W. IvanGoddeeris, M.Teale, A.J.Groocock, C.M.Kemp, Stephen J.Stagg, D.A.[Cytotoxic T cells elicited in cattle challenged with Theileria parva (Muguga): Evidence for restriction by class I MHC determinants and parasite strain specificity]Cytotoxic T cells elicited in cattle challenged with Theileria parva (Muguga): Evidence for restriction by class I MHC determinants and parasite strain specificity

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