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Kemp, Stephen J.[Automation of the Lymphocytotoxicity test for the detection of anti-class II antibodies]Automation of the Lymphocytotoxicity test for the detection of anti-class II antibodies
Kemp, Stephen J.Teale, A.J.[An assay for the fully automated reading of the lymphocytotoxicity test and its application to the detection of bovine class I and class II MHC antigens]An assay for the fully automated reading of the lymphocytotoxicity test and its application to the detection of bovine class I and class II MHC antigens

Malaria and trypanosomiasis are vector-borne protozoal diseases which disproportionately affect the poor. Both give rise to immense human suffering; malaria exerts its effect directly on human health, while trypanosomiasis causes damage largely though its effect on the health and productivity of ...


Foote, S.J.Iraqi, F.A.Kemp, Stephen J.[Controlling malaria and African trypanosomiasis: The role of the mouse]Controlling malaria and African trypanosomiasis: The role of the mouse

To map the genetic sources of trypanotolerance in mice, a linkage analysis of survival following trypanosome challenge was performed by selective genotyping in a large F2 population produced by crossing the resistant C57BL/6 and susceptible BALB/c inbred mouse lines. We report evidence of a chrom...


Kemp, Stephen J.Darvasi, A.Soller, M.Teale, A.J.[Genetic control of resistance to trypanosomiasis]Genetic control of resistance to trypanosomiasis

To examine differences in cytokine profiles that may confer tolerance/susceptibility to bovine African trypanosomiasis, N'Dama (trypanotolerant, n = 8) and Boran (trypanosusceptible, n = 8) cattle were experimentally challenged with Trypanosoma congolense. Blood samples were collected over a 34-d...


O'Gorman, G.M.Park, S.D.E.Hill, E.W.Meade, K.G.Mitchell, L.C.Agaba, MorrisGibson, John P.Hanotte, Olivier H.Naessens, JanKemp, Stephen J.MacHugh, D.E.[Cytokine mRNA profiling of peripheral blood mononuclear cells from trypanotolerant and trypanosusceptible cattle infected with Trypanosoma congolense]Cytokine mRNA profiling of peripheral blood mononuclear cells from trypanotolerant and trypanosusceptible cattle infected with Trypanosoma congolense

Background: Familial pancreatic cancer (FPC) describes a group of families where the inheritance of pancreatic cancer is consistent with an autosomal-dominant mode of inheritance. The 4q32-34 region has been previously identified as a potential locus for FPC in a large American family.


Earl, J.Yan, L.Vitone, L.J.Risk, J.Kemp, Stephen J.McFaul, C.Neoptolemos, J.P.Greenhalf, W.Kress, R.Sina-Frey, M.Hahn, S.Rieder, H.Bartsch, D.K.[Evaluation of the 4q32-34 Locus in European familial pancreatic cancer]Evaluation of the 4q32-34 Locus in European familial pancreatic cancer
Iraqi, F.A.Kemp, Stephen J.Teale, A.J.[Fine mapping of trypanosomiasis resistance QTLs in mice using advanced intercross lines]Fine mapping of trypanosomiasis resistance QTLs in mice using advanced intercross lines

An international multidisciplinary consortium is conducting a programme of research on the host response to trypanosome infection. This builds upon quantitative trait loci (QTL) mapping which identified genome regions influencing susceptibility to pathology following T. congolense infection in bo...


Kemp, Stephen J.Hanotte, Olivier H.Agaba, MorrisNoyes, H.A.Gibson, John P.Archibald, A.L.Rennie, C.Hulme, H.Brass, A.[Genomics approaches to study the biology underlying resistance to trypanosomiasis--some unexpected lessons]Genomics approaches to study the biology underlying resistance to trypanosomiasis--some unexpected lessons
Morrison, W. IvanGoddeeris, M.Teale, A.J.Groocock, C.M.Kemp, Stephen J.Stagg, D.A.[Cytotoxic T cells elicited in cattle challenged with Theileria parva (Muguga): Evidence for restriction by class I MHC determinants and parasite strain specificity]Cytotoxic T cells elicited in cattle challenged with Theileria parva (Muguga): Evidence for restriction by class I MHC determinants and parasite strain specificity

BACKGROUND: The advent of genotyping by Next Generation Sequencing has enabled rapid discovery of thousands of single nucleotide polymorphism (SNP) markers and high throughput genotyping of large populations at an affordable cost. Genotyping by sequencing (GBS), a reduced representation library s...


Onyango, M.G.Aitken, N.C.Jack, C.Chuah, A.Oguya, J.Djikeng, AppolinaireKemp, Stephen J.Bellis, G.A.Nicholas, A.Walker, P.J.Duchemin, J.B.[Genotyping of whole genome amplified reduced representation libraries reveals a cryptic population of Culicoides brevitarsis in the Northern Territory, Australia]Genotyping of whole genome amplified reduced representation libraries reveals a cryptic population of Culicoides brevitarsis in the Northern Territory, Australia

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