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Marshall, KarenGibson, John P.Okeyo Mwai, AllyMwacharo, Joram M.Haile, AynalemGetachew, TesfayeMrode, Raphael A.Kemp, Stephen J.[Livestock genomics for developing countries―African examples in practice]Livestock genomics for developing countries―African examples in practice

Background: The history of African indigenous cattle and their adaptation to environmental and human selection pressure is at the root of their remarkable diversity. Characterization of this diversity is an essential step towards understanding the genomic basis of productivity and adaptation to s...


Kim, JaeminHanotte, Olivier H.Okeyo Mwai, AllyDessie, TadelleSalim, BashirDiallo, BoubacarAgaba, MorrisKwondo KimWoori KwakSamsun SungSeo, MinseokJeong, HyeonsooKwon, TaehyungTaye, MengistieSong, Ki-DukLim, DajeongSeoae ChoLee, Hyun-JeongDuhak YoonSung Jong OhKemp, Stephen J.Hak-Kyo LeeHeebal Kim[The genome landscape of indigenous African cattle]The genome landscape of indigenous African cattle

To map the genetic sources of trypanotolerance in mice, a linkage analysis of survival following trypanosome challenge was performed by selective genotyping in a large F2 population produced by crossing the resistant C57BL/6 and susceptible BALB/c inbred mouse lines. We report evidence of a chrom...


Kemp, Stephen J.Darvasi, A.Soller, M.Teale, A.J.[Genetic control of resistance to trypanosomiasis]Genetic control of resistance to trypanosomiasis

Microarrays are an important and widely used tool. Applications include capturing genomic DNA for high-throughput sequencing in addition to the traditional monitoring of gene expression and identifying DNA copy number variations. Sequence mismatches between probe and target strands are known to a...


Rennie, C.Noyes, H.A.Kemp, Stephen J.Hulme, H.Brass, A.Hoyle, D.C.[Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays]Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays

To assess the level and spatial pattern of genetic diversity of the common dormouse, Muscardinus avellanarius, we developed polymorphic microsatellite loci from partial genomic libraries enriched for microsatellite motifs. Ten dinucleotide polymorphic microsatellites were isolated and levels of g...


Naim, D.M.D.Kemp, Stephen J.Telfer, S.Watts, P.C.[Isolation and characterization of 10 microsatellite loci in the common dormouse Muscardinus avellanarius]Isolation and characterization of 10 microsatellite loci in the common dormouse Muscardinus avellanarius

Conventional disciplinary research approach is losing momentum in the face of dynamic health challenges of the 21st century. There is a need for a new, suitable approach, to tackle these emerging and re-emerging human and animal diseases through integrating livestock and human health research in ...


Tibbo, MarkosSchelling, E.Grace, DeliaBishop, Richard P.Taracha, E.A.Kemp, Stephen J.Ameni, G.Dawo, F.Randolph, Thomas F.[Cross-disciplinary and participatory livestock and human health research for successful control of zoonoses in the developing world]Cross-disciplinary and participatory livestock and human health research for successful control of zoonoses in the developing world
Iraqi, F.A.Kemp, Stephen J.Teale, A.J.[Fine mapping of trypanosomiasis resistance QTLs in mice using advanced intercross lines]Fine mapping of trypanosomiasis resistance QTLs in mice using advanced intercross lines

We describe 10 polymorphic tetranucleotide microsatellite loci from the eastern Canary Island lacertid lizard, Gallotia atlantica. Loci were isolated from a partial genomic library that had been enriched for AAAG repeat sequence. All loci were highly polymorphic (eight alleles or more) with obser...


Bloor, P.Laguna, I.H.B.Kemp, Stephen J.[Highly polymorphic tetranucleotide microsatellite loci for the eastern Canary Island lizard, Gallotia atlantica]Highly polymorphic tetranucleotide microsatellite loci for the eastern Canary Island lizard, Gallotia atlantica

Under most circumstances, certain breeds of domestic ruminants show a remarkable resistance to the effects of African trypanosomiasis: they can tolerate the presence of parasites while apparently controlling levels of parasitaemia and, crucially, not showing the the severe anaemia and production ...


Kemp, Stephen J.Teale, A.J.[Genetic basis of trypanotolerance in cattle and mice]Genetic basis of trypanotolerance in cattle and mice

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