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Streptomyces spp. are a highly diverse group of bacteria most of which are soil-inhabiting saprophytes. A few are plant pathogens that produce a family of phytotoxins called thaxtomins and cause significant economic losses, e.g., by reducing the marketability of potato tubers (Solanum tuberosum)....


Natsume, M.Nagagata, A.Aittamaa, M.Okaniwa, N.Somervuo, P.Fiedler, H.P.Kreuze, J.F.Rokka, V.M.Bang, H.Kawaide, H.Valkonen, J.P.T.[Phytotoxin produced by the netted scab pathogen, Streptomyces turgidiscabies strain 65, isolated in Sweden]Phytotoxin produced by the netted scab pathogen, Streptomyces turgidiscabies strain 65, isolated in Sweden

Wang, F.Sun, Y.Ruan, J.Chen, R.Chen, X.Kreuze, J.F.Fei, Z.J.Zhu, X.Gao, S.[Using small RNA deep sequencing data to detect human viruses.]Using small RNA deep sequencing data to detect human viruses.

Reverse-transcribing viruses, which synthesize a copy of genomic DNA from an RNA template, are widespread in animals, plants, algae, and fungi. This broad distribution suggests the ancient origin(s) of these viruses, possibly concomitant with the emergence of eukaryotes. Reverse-transcribing viru...


Hull, R.Johnson, W.Kreuze, J.F.Lindemann, D.Llorens, C.Lockhart, B.E.L.Mayer, J.Muller, E.Olszewski, N.E.Pappu, H.R.Pooggin, M.M.Richert-Poggeler, K.R.Sabanadzovic, S.Sanfacon, H.Schoelz, J.E.Seal, S.Stavolone, L.Stoye, J.P.Teycheney, P.Y.Tristem, M.Koonin, E.V.Kuhn, J.H.Krupovic, M.Blomberg, J.Coffin, J.M.Dasgupta, I.Fan, H.Geering, A.D.Gifford, R.Harrach, B.[Ortervirales: New virus order unifying five families of reverse-transcribing viruses]Ortervirales: New virus order unifying five families of reverse-transcribing viruses

Sweetpotato chlorotic stunt virus (SPCSV; genus Crinivirus, family Closteroviridae) is one of the most important pathogens of sweetpotato (Ipomoea batatas L.). It can reduce yields by 50% by itself and cause various synergistic disease complexes when co-infecting with other viruses, including swe...


Kreuze, J.F.Klein, I.S.Ghislain, M.Valkonen, J.P.T.Untiveros, M.Cuéllar, Wilmer J.Lajo, G.Cipriani, P.[RNA silencing-mediated resistance to a crinivirus (Closteroviridae) in cultivated sweetpotato (Ipomoea batatas L.) and development of sweetpotato virus disease following co-infection with a potyvirus.]RNA silencing-mediated resistance to a crinivirus (Closteroviridae) in cultivated sweetpotato (Ipomoea batatas L.) and development of sweetpotato virus disease following co-infection with a potyvirus.

Double-stranded RNA (dsRNA)-specific endonucleases belonging to RNase III classes 3 and 2 process dsRNA precursors to small interfering RNA (siRNA) or microRNA, respectively, thereby initiating and amplifying RNA silencing-based antiviral defense and gene regulation in eukaryotic cells. However, ...


Kreuze, J.F.Savenkov, E.I.Cuéllar, Wilmer J.Xiangdong LiValkonen, J.P.T.[Viral class 1 RNase III involved in suppression of RNA silencing.]Viral class 1 RNase III involved in suppression of RNA silencing.
Untiveros, M.Fuentes, S.Kreuze, J.F.[Molecular variability of sweet potato feathery mottle virus and other potyviruses infecting sweet potato in Peru.]Molecular variability of sweet potato feathery mottle virus and other potyviruses infecting sweet potato in Peru.

Sweet potato (Ipomoea batatas) is an important subsistence and famine reserve crop grown in developing countries where Sweet potato chlorotic stunt virus (SPCSV; Closteroviridae), a single-stranded RNA (ssRNA) crinivirus, synergizes unrelated viruses in co-infected sweet potato plants. The most s...


Cuéllar, Wilmer J.Kreuze, J.F.Rajamaki, M.L.Cruzado, K.R.Untiveros, M.Valkonen, J.P.T.[Elimination of antiviral defense by viral RNase III.]Elimination of antiviral defense by viral RNase III.

The largest extant RNA genomes are found in two diverse families of positive-strand RNA viruses, the animal Coronaviridae and the plant Closteroviridae. Comparative analysis of the viruses from the latter family reveals three levels of gene conservation. The most conserved gene module defines RNA...


Dolja, V.V.Kreuze, J.F.Valkonen, J.P.T.[Comparative and functional genomics of closteroviruses.]Comparative and functional genomics of closteroviruses.

We report the first identification of novel viruses, and sequence of an entire viral genome, by a single step of high-throughput parallel sequencing of small RNAs from diseased, as well as symptomless plants. Contigs were assembled from sequenced total siRNA from plants using small sequence assem...


Kreuze, J.F.Pérez, A.Untiveros, M.Quispe, D.Fuentes, S.Barker, I.Simon, R.[Complete viral genome sequence and discovery of novel viruses by deep sequencing of small RNAs: A generic method for diagnosis, discovery and sequencing of viruses.]Complete viral genome sequence and discovery of novel viruses by deep sequencing of small RNAs: A generic method for diagnosis, discovery and sequencing of viruses.

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