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Human Respiratory syncytial virus (hRSV) and human metapneumovirus (hMPV) are the two major etiological viral agents of lower respiratory tract diseases, affecting mainly infants, young children and the elderly. Although the infection of both viruses trigger an antiviral immune response that medi...


González, A.E.Lay, M.K.Jara, E.L.Espinoza, J.A.Gómez, R.S.Soto, J.Rivera, C.A.Abarca, K.Bueno, S.M.Riedel, C.A.Kalergis, A.M.[Aberrant T cell immunity triggered by human respiratory syncytial virus and human metapneumovirus infection]Aberrant T cell immunity triggered by human respiratory syncytial virus and human metapneumovirus infection

The Human Respiratory Syncytial Virus (hRSV) is a major cause of acute lower respiratory tract infections (ARTIs) and high rates of hospitalizations in children and in the elderly worldwide. Symptoms of hRSV infection include bronchiolitis and pneumonia. The lung pathology observed during hRSV in...


Canedo-Marroquín, G.Acevedo-Acevedo, O.Rey-Jurado, E.Saavedra, J.M.Lay, M.K.Bueno, S.M.Riedel, C.A.Kalergis, A.M.[Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors: A Synergic Inhibition of Both Innate and Adaptive Immunity]Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors: A Synergic Inhibition of Both Innate and Adaptive Immunity

Human metapneumovirus (hMPV) is a respiratory virus, first reported the year 2001. Since then, it has been described as one of the main etiological agents that causes acute lower respiratory tract infections (ALRTIs), which is characterized by symptoms such as bronchiolitis, wheezing and coughing...


Soto, J.A.Gálvez, N.M.S.Benavente, F.M.Pizarro-Ortega, M.S.Lay, M.K.Riedel, C.Bueno, S.M.Gonzalez, P.A.Kalergis, A.M.[Human metapneumovirus: Mechanisms and molecular targets used by the virus to avoid the immune system]Human metapneumovirus: Mechanisms and molecular targets used by the virus to avoid the immune system

Vaccines have significantly reduced the detrimental effects of numerous human infectious diseases worldwide, helped to reduce drastically child mortality rates and even achieved eradication of major pathogens, such as smallpox. These achievements have been possible due to a dedicated effort for v...


Rey-Jurado, E.Tapia, F.Muñoz-Durango, N.Lay, M.K.Carreño, L.J.Riedel, C.A.Bueno, S.M.Genzel, Y.Kalergis, A.M.[Assessing the importance of domestic vaccine manufacturing centers: An overview of immunization programs, vaccine manufacture, and distribution]Assessing the importance of domestic vaccine manufacturing centers: An overview of immunization programs, vaccine manufacture, and distribution

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