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Article

Autor: Tapia, Oscar Riquelme, Ismael Leal, Pamela Sandoval, Alejandra Aedo, Susana Weber, Helga Letelier, Pablo Bellolio, Enrique Villaseca, Miguel Garcia, Patricia Carlos Roa, Juan

Signaling pathway alterations are important in the development of gastric cancer (GC). Deregulation of the PI3K/AKT/mTOR pathway plays a crucial role in the regulation of multiple cellular functions including cell growth, proliferation, metabolism, and angiogenesis. Our goal was to assess express...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3536

Repositorio Digital Universidad Católica de Temuco
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Tapia, Oscar ,  Riquelme, Ismael ,  Leal, Pamela ,  Sandoval, Alejandra ,  Aedo, Susana ,  Weber, Helga ,  Letelier, Pablo ,  Bellolio, Enrique ,  Villaseca, Miguel ,  Garcia, Patricia ,  Carlos Roa, Juan ,  [The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance] ,  The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance
Article

Autor: Buchegger, Kurt Lopez, Jaime Ili, Carmen Riquelme, Ismael Letelier, Pablo Guzman, Pablo Bellolio, Enrique Corvalan, Alejandro H. Brebi, Priscilla Carlos Roa, Juan

Reprimo (RPRM) is a potential p53-dependent tumor suppressor gene, which plays an important role in cell cycle arrest at G(2)/M checkpoint. The aim of this study was to characterize RPRM protein expression in breast cancer tissues and its relation with clinic-pathologic features and proliferation...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3600

Repositorio Digital Universidad Católica de Temuco
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Buchegger, Kurt ,  Lopez, Jaime ,  Ili, Carmen ,  Riquelme, Ismael ,  Letelier, Pablo ,  Guzman, Pablo ,  Bellolio, Enrique ,  Corvalan, Alejandro H. ,  Brebi, Priscilla ,  Carlos Roa, Juan ,  [Immunohistochemical expression of RPRM is associated with low expression of proliferation marker Ki67 in patients with breast cancer] ,  Immunohistochemical expression of RPRM is associated with low expression of proliferation marker Ki67 in patients with breast cancer
Article

Autor: Buchegger, Kurt Ili, Carmen Riquelme, Ismael Letelier, Pablo Corvalan, Alejandro H. Brebi, Priscilla Huang, Tim Hui Ming Carlos Roa, Juan
Enlace original: http://repositoriodigital.uct.cl/handle/10925/3895

Repositorio Digital Universidad Católica de Temuco
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Buchegger, Kurt ,  Ili, Carmen ,  Riquelme, Ismael ,  Letelier, Pablo ,  Corvalan, Alejandro H. ,  Brebi, Priscilla ,  Huang, Tim Hui Ming ,  Carlos Roa, Juan ,  [Reprimo as a modulator of cell migration and invasion in the MDA-MB-231 breast cancer cell line] ,  Reprimo as a modulator of cell migration and invasion in the MDA-MB-231 breast cancer cell line
Article

Autor: Ili, Carmen G. Brebi, Priscilla Garcia, Patricia Leal, Pamela Lopez, Jaime Tapia, Oscar Letelier, Pablo Weber, Helga Castillo, Jonathan Roa, Juan C.

Overexpression of Short and Raji variants of Cellular FLICE-like inhibitory protein (c-FLIP) is capable of inhibiting apoptosis, while the function of the Long isoform depends of c-FLIPL concentration in cells. The aim of this study was to determine the effects of c-FLIPL knockdown in cervical ce...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3558

Repositorio Digital Universidad Católica de Temuco
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Ili, Carmen G. ,  Brebi, Priscilla ,  Garcia, Patricia ,  Leal, Pamela ,  Lopez, Jaime ,  Tapia, Oscar ,  Letelier, Pablo ,  Weber, Helga ,  Castillo, Jonathan ,  Roa, Juan C. ,  [Effects of c-FLIPL Knockdown in Cervical Uterine Carcinoma Cell Lines] ,  Effects of c-FLIPL Knockdown in Cervical Uterine Carcinoma Cell Lines
Article

Autor: Letelier, Pablo Guzman Oyarzo, Neftali Medina Schwerter, Gustavo Calcumil, Luis Huencho, Pamela Mora, Jonathan Quinones, Francisco Jara, Jorge Reyno, Cristobal Farias, Jorge G. Herrera Belen, Belen Brebi, Priscilla Riquelme, Ismael San Martin, Andres
Enlace original: http://repositoriodigital.uct.cl/handle/10925/3695

Repositorio Digital Universidad Católica de Temuco
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Letelier, Pablo ,  Guzman Oyarzo, Neftali ,  Medina Schwerter, Gustavo ,  Calcumil, Luis ,  Huencho, Pamela ,  Mora, Jonathan ,  Quinones, Francisco ,  Jara, Jorge ,  Reyno, Cristobal ,  Farias, Jorge G. ,  Herrera Belen, Belen ,  Brebi, Priscilla ,  Riquelme, Ismael ,  San Martin, Andres ,  [WORKFLOW OPTIMIZATION IN A CLINICAL LABORATORY USING LEAN MANAGEMENT PRINCIPLES IN THE PRE-ANALYTICAL PHASE] ,  WORKFLOW OPTIMIZATION IN A CLINICAL LABORATORY USING LEAN MANAGEMENT PRINCIPLES IN THE PRE-ANALYTICAL PHASE
Review

Autor: Reyes, Maria Elena Riquelme, Ismael Salvo, Tomas Zanella, Louise Letelier, Pablo Brebi, Priscilla

Fucoidans are sulphated polysaccharides that can be obtained from brown seaweed and marine invertebrates. They have anti-cancer properties, through their targeting of several signaling pathways and molecular mechanisms within malignant cells. This review describes the chemical structure diversity...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3456

Repositorio Digital Universidad Católica de Temuco
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Reyes, Maria Elena ,  Riquelme, Ismael ,  Salvo, Tomas ,  Zanella, Louise ,  Letelier, Pablo ,  Brebi, Priscilla ,  [Brown Seaweed Fucoidan in Cancer: Implications in Metastasis and Drug Resistance] ,  Brown Seaweed Fucoidan in Cancer: Implications in Metastasis and Drug Resistance
Review

Autor: Riquelme, Ismael Letelier, Pablo Riffo Campos, Angela L. Brebi, Priscilla Carlos Roa, Juan

Gastric cancer is the third leading cause of cancer mortality worldwide. Unfortunately, most gastric cancer cases are diagnosed in an advanced, non-curable stage and with a limited response to chemotherapy. Drug resistance is one of the most important causes of therapy failure in gastric cancer p...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3479

Repositorio Digital Universidad Católica de Temuco
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Riquelme, Ismael ,  Letelier, Pablo ,  Riffo Campos, Angela L. ,  Brebi, Priscilla ,  Carlos Roa, Juan ,  [Emerging Role of miRNAs in the Drug Resistance of Gastric Cancer] ,  Emerging Role of miRNAs in the Drug Resistance of Gastric Cancer
Review

Autor: Letelier, Pablo Riquelme, Ismael Hernández Monsalves, Alfonso Guzman Oyarzo, Neftali Farias, Jorge G. Carlos Roa, Juan

Biliary tract cancers (BTCs) are a group of highly aggressive malignant tumors with a poor prognosis. The current diagnosis is based mainly on imaging and intraoperative exploration due to brush cytology having a low sensitivity and the standard markers, such as carcinoembryonic antigen (CEA) and...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3575

Repositorio Digital Universidad Católica de Temuco
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Letelier, Pablo ,  Riquelme, Ismael ,  Hernández Monsalves, Alfonso ,  Guzman Oyarzo, Neftali ,  Farias, Jorge G. ,  Carlos Roa, Juan ,  [Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers] ,  Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers
Article

Autor: Riquelme, Ismael Tapia, Oscar Leal, Pamela Sandoval, Alejandra Varga, Matthew G. Letelier, Pablo Buchegger, Kurt Bizama, Carolina Espinoza, Jaime A. Peek, Richard M. Carlos Araya, Juan Carlos Roa, Juan
Enlace original: http://repositoriodigital.uct.cl/handle/10925/3742

Repositorio Digital Universidad Católica de Temuco
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Riquelme, Ismael ,  Tapia, Oscar ,  Leal, Pamela ,  Sandoval, Alejandra ,  Varga, Matthew G. ,  Letelier, Pablo ,  Buchegger, Kurt ,  Bizama, Carolina ,  Espinoza, Jaime A. ,  Peek, Richard M. ,  Carlos Araya, Juan ,  Carlos Roa, Juan ,  [miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway] ,  miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway
Article

Autor: Letelier, Pablo Garcia, Patricia Leal, Pamela Alvarez, Hector Ili, Carmen Lopez, Jaime Castillo, Jonathan Brebi, Priscilla Roa, Juan Carlos

The development of miRNA-based therapeutics represents a new strategy in cancer treatment. The objectives of this study were to evaluate the differential expression of microRNAs in gallbladder cancer (GBC) and to assess the functional role of miR-1 and miR-145 in GBC cell behavior. A profile of m...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3858

Repositorio Digital Universidad Católica de Temuco
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Letelier, Pablo ,  Garcia, Patricia ,  Leal, Pamela ,  Alvarez, Hector ,  Ili, Carmen ,  Lopez, Jaime ,  Castillo, Jonathan ,  Brebi, Priscilla ,  Roa, Juan Carlos ,  [miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer] ,  miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer

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