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Review

Autor: Reyes, Maria Elena Riquelme, Ismael Salvo, Tomas Zanella, Louise Letelier, Pablo Brebi, Priscilla

Fucoidans are sulphated polysaccharides that can be obtained from brown seaweed and marine invertebrates. They have anti-cancer properties, through their targeting of several signaling pathways and molecular mechanisms within malignant cells. This review describes the chemical structure diversity...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3456

Repositorio Digital Universidad Católica de Temuco
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Reyes, Maria Elena ,  Riquelme, Ismael ,  Salvo, Tomas ,  Zanella, Louise ,  Letelier, Pablo ,  Brebi, Priscilla ,  [Brown Seaweed Fucoidan in Cancer: Implications in Metastasis and Drug Resistance] ,  Brown Seaweed Fucoidan in Cancer: Implications in Metastasis and Drug Resistance
Review

Autor: Riquelme, Ismael Letelier, Pablo Riffo Campos, Angela L. Brebi, Priscilla Carlos Roa, Juan

Gastric cancer is the third leading cause of cancer mortality worldwide. Unfortunately, most gastric cancer cases are diagnosed in an advanced, non-curable stage and with a limited response to chemotherapy. Drug resistance is one of the most important causes of therapy failure in gastric cancer p...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3479

Repositorio Digital Universidad Católica de Temuco
Enlace permanente
Riquelme, Ismael ,  Letelier, Pablo ,  Riffo Campos, Angela L. ,  Brebi, Priscilla ,  Carlos Roa, Juan ,  [Emerging Role of miRNAs in the Drug Resistance of Gastric Cancer] ,  Emerging Role of miRNAs in the Drug Resistance of Gastric Cancer
Review

Autor: Letelier, Pablo Riquelme, Ismael Hernández Monsalves, Alfonso Guzman Oyarzo, Neftali Farias, Jorge G. Carlos Roa, Juan

Biliary tract cancers (BTCs) are a group of highly aggressive malignant tumors with a poor prognosis. The current diagnosis is based mainly on imaging and intraoperative exploration due to brush cytology having a low sensitivity and the standard markers, such as carcinoembryonic antigen (CEA) and...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3575

Repositorio Digital Universidad Católica de Temuco
Enlace permanente
Letelier, Pablo ,  Riquelme, Ismael ,  Hernández Monsalves, Alfonso ,  Guzman Oyarzo, Neftali ,  Farias, Jorge G. ,  Carlos Roa, Juan ,  [Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers] ,  Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers
Review

Autor: Farias, Jorge G. Molina, Victor M. Carrasco, Rodrigo A. Zepeda, Andrea B. Figueroa Villalobos, Elías Letelier, Pablo Castillo, Rodrigo L.

Oxidative stress (OS) refers to the imbalance between the generation of reactive oxygen species (ROS) and the ability to scavenge these ROS by endogenous antioxidant systems, where ROS overwhelms the antioxidant capacity. Excessive presence of ROS results in irreversible damage to cell membranes,...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/3994

Repositorio Digital Universidad Católica de Temuco
Enlace permanente
Farias, Jorge G. ,  Molina, Victor M. ,  Carrasco, Rodrigo A. ,  Zepeda, Andrea B. ,  Figueroa Villalobos, Elías ,  Letelier, Pablo ,  Castillo, Rodrigo L. ,  [Antioxidant Therapeutic Strategies for Cardiovascular Conditions Associated with Oxidative Stress] ,  Antioxidant Therapeutic Strategies for Cardiovascular Conditions Associated with Oxidative Stress
Review

Autor: Letelier, Pablo Encina, Nicole Morales, Pablo Riffo, Alejandra Silva, Halett Riquelme, Ismael Guzman Oyarzo, Neftali

COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, which has given rise to a global sanitary emergency. The clinical characteristics of COVID-19 are varied and can range from an asymptomatic infection to a mild to severe pneumonia. Recent studies have shown that different laborator...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/4137

Repositorio Digital Universidad Católica de Temuco
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Letelier, Pablo ,  Encina, Nicole ,  Morales, Pablo ,  Riffo, Alejandra ,  Silva, Halett ,  Riquelme, Ismael ,  Guzman Oyarzo, Neftali ,  [ROLE OF BIOCHEMICAL MARKERS IN THE MONITORING OF COVID-19 PATIENTS] ,  ROLE OF BIOCHEMICAL MARKERS IN THE MONITORING OF COVID-19 PATIENTS
Review

Autor: Guzman Oyarzo, Neftali Vega, Mario Reyes, Franco Guzman-Oyarzo, Dina Andaur Rademacher, Marcela Boguen, Rodrigo Letelier, Pablo

There is an important interindividual variability in dose requirement for coumarinic anticoagulants, which could be explained by genetic and non-genetic factors. Among hereditary factors, there are gene polymorphisms that code the therapeutic target and the main enzyme responsible for their metab...

Enlace original: http://repositoriodigital.uct.cl/handle/10925/4177

Repositorio Digital Universidad Católica de Temuco
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Guzman Oyarzo, Neftali ,  Vega, Mario ,  Reyes, Franco ,  Guzman-Oyarzo, Dina ,  Andaur Rademacher, Marcela ,  Boguen, Rodrigo ,  Letelier, Pablo ,  [Pharmacogenomics of vitamin K antagonists] ,  Pharmacogenomics of vitamin K antagonists

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