Shiga toxin-producing Escherichia coli (STEC) cause gastrointestinal illnesses including non-bloody or bloody diarrhoea, haemorrhagic colitis (HC), and the haemolytic uremic syndrome (HUS). To investigate the occurrence of STEC among grazing dromedaries from Kenya, E. coli isolated from fecal mat...
Baschera, M.
,
Cernela, N.
,
Stevens, M.J.A.
,
Liljander, Anne M.
,
Jores, Joerg
,
Max Corman, V.
,
Nüesch-Inderbinen, M.
,
Stephan, R.
,
[Shiga toxin-producing Escherichia coli (STEC) isolated from fecal samples of African dromedary camels]
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Shiga toxin-producing Escherichia coli (STEC) isolated from fecal samples of African dromedary camels
Mycoplasmas are the smallest free-living organisms and cause a number of economically important diseases affecting humans, animals, insects, and plants. Here, we demonstrate that highly virulent Mycoplasma mycoides subspecies capri (Mmc) can be fully attenuated via targeted deletion of non-essent...
Jores, Joerg
,
Ma, L.
,
Ssajjakambwe, Paul
,
Schieck, Elise G.
,
Liljander, Anne M.
,
Chandran, S.
,
Stoffel, M.H.
,
Cippa, V.
,
Arfi, Y.
,
Assad-Garcia, N.
,
Falquet, L.
,
Sirand-Pugnet, P.
,
Blanchard, Alain
,
Lartigue, C.
,
Posthaus, H.
,
Labroussaa, F.
,
Vashee, S.
,
[Removal of a subset of non-essential genes fully attenuates a highly virulent Mycoplasma strain]
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Removal of a subset of non-essential genes fully attenuates a highly virulent Mycoplasma strain
Mycoplasma species are responsible for several economically significant livestock diseases for which there is a need for new and improved vaccines. Most of the existing mycoplasma vaccines are attenuated strains that have been empirically obtained by serial passages or by chemical mutagenesis. Th...
Lartigue, C.
,
Valverde Timana, Y.
,
Labroussaa, F.
,
Schieck, Elise G.
,
Liljander, Anne M.
,
Sacchini, Flavio
,
Posthaus, H.
,
Batailler, B.
,
Sirand-Pugnet, P.
,
Vashee, S.
,
Jores, Joerg
,
Blanchard, Alain
,
[Attenuation of a pathogenic Mycoplasma strain by modification of the obg gene by using synthetic biology approaches]
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Attenuation of a pathogenic Mycoplasma strain by modification of the obg gene by using synthetic biology approaches