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Five adult Boran cattle (Bos indicus), infected with a clone of Trypanosoma congolense IL13-E3 three years earlier and treated, were re-challenged with the same clone. Changes in the peripheral blood were monitored twice weekly, and events in the bone marrow (BM) were assessed by weekly biopsies ...


Anosa, V.O.Logan-Henfrey, L.L.Wells, C.W.[The haematology of Trypanosoma congolense infection in cattle. I. Sequential cytomorphological changes in the blood and bone marrow of Boran cattle]The haematology of Trypanosoma congolense infection in cattle. I. Sequential cytomorphological changes in the blood and bone marrow of Boran cattle

This study compared the changes in the bone marrow (BM) of five trypanotolerant N'Dama cattle with those of four trypanosusceptible Boran cattle during trypanosome infection. In the early parasitaemic phase, from 12 to 21 days postinfection (DPI), tsetse transmitted primary Trypanosoma congolense...


Logan-Henfrey, L.L.Anosa, V.O.Wells, C.W.[The role of the bone marrow in bovine trypanotolerance. 1. Changes in blood and bone marrow in Trypanosoma congolense-infected cattle]The role of the bone marrow in bovine trypanotolerance. 1. Changes in blood and bone marrow in Trypanosoma congolense-infected cattle

A bobine cDNA encoding erythropoietin (Epo) was isolated by polymerase chain reaction (PCR) amplification and screening of a bovine kidney cDNA library. The sequenced cDNA has a length of 1312 bp and an open reading frame that encodes a predicted 192-amino-acid (aa) protein, including a putative ...


Suliman, H.B.Majiwa, P.A.O.Feldman, B.F.Mertens, B.Logan-Henfrey, L.L.[Cloning of a cDNA encoding bovine erythropoietin and analysis of its transcription in selected tissues]Cloning of a cDNA encoding bovine erythropoietin and analysis of its transcription in selected tissues

Acute Trypanosoma congolense infection induced moderate, transient anemia in N'Dama cattle (trypanotolerant) and severe anemia in Boran cattle (trypanosusceptible). Erythropoietin receptor (EpoR) was cloned and sequenced from the two breeds of cattle. A single position mutation of Tyr in the Bora...


Suliman, H.B.Logan-Henfrey, L.L.Majiwa, P.A.O.Ole-MoiYoi, O.K.Feldman, B.F.[Analysis of erythropoietin and erythropoietin receptor genes expression in cattle during acute infection with Trypanosoma congolense]Analysis of erythropoietin and erythropoietin receptor genes expression in cattle during acute infection with Trypanosoma congolense

N'Dama (Bos taurus) cattle are known to tolerate trypanosome infections, developing less severe anemia and lower parasitemia, compared to Boran (Bos indicus) cattle. Young calves were also reported to be more resistant to trypanosomiasis than adult cattle. To expore the basis for this resistance,...


Andrianarivo, A.G.Muiya, P.Logan-Henfrey, L.L.[Trypanosoma congolense: High erythropoietic potential in infected yearling cattle during the acute phase of the anemia]Trypanosoma congolense: High erythropoietic potential in infected yearling cattle during the acute phase of the anemia

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