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Sequential biopsies of sternal bone marrow (BM) of three trypanosusceptible Boran and three trypanotolerant N'Dama cattle were examined by light and transmission electron microscopy before and up to 112 days postinfection (DPI) with Trypanosoma congolense. Before infection, the percentage of cell...


Anosa, V.O.Logan-Henfrey, L.L.Wells, C.W.[The role of the bone marrow in bovine trypanotolerance. II. Macrophage function in Trypanosoma congolense - infected cattle]The role of the bone marrow in bovine trypanotolerance. II. Macrophage function in Trypanosoma congolense - infected cattle

This study compared the changes in the bone marrow (BM) of five trypanotolerant N'Dama cattle with those of four trypanosusceptible Boran cattle during trypanosome infection. In the early parasitaemic phase, from 12 to 21 days postinfection (DPI), tsetse transmitted primary Trypanosoma congolense...


Logan-Henfrey, L.L.Anosa, V.O.Wells, C.W.[The role of the bone marrow in bovine trypanotolerance. 1. Changes in blood and bone marrow in Trypanosoma congolense-infected cattle]The role of the bone marrow in bovine trypanotolerance. 1. Changes in blood and bone marrow in Trypanosoma congolense-infected cattle

A bioassay was used to measure erythropoietin (EPO) concentrations in calves with haemorrhagic anaemia due to blood loss and in calves with anaemia due to Trypanosoma congolense infection. The bioactivity of EPO was measured in the assay by its stimulatory effect on 125I-deoxyuridine incorporatio...


Buza, J.J.Logan-Henfrey, L.L.Andrianarivo, A.G.Williams, D.J.L.[Rise in erythropoietin concentrations in experimental Trypanosoma congolense infection of calves]Rise in erythropoietin concentrations in experimental Trypanosoma congolense infection of calves

N'Dama (Bos taurus) cattle are known to tolerate trypanosome infections, developing less severe anemia and lower parasitemia, compared to Boran (Bos indicus) cattle. Young calves were also reported to be more resistant to trypanosomiasis than adult cattle. To expore the basis for this resistance,...


Andrianarivo, A.G.Muiya, P.Logan-Henfrey, L.L.[Trypanosoma congolense: High erythropoietic potential in infected yearling cattle during the acute phase of the anemia]Trypanosoma congolense: High erythropoietic potential in infected yearling cattle during the acute phase of the anemia

Trypanosomiasis is a serious constraint to livestock production in sub-Saharan Africa. Some breeds of cattle are genetically more resistant to the pathogenic effects of trypanosome infection. We measured B-cell activation and the quantity and isotype of antibody produced at the cellular level in ...


Taylor, K.A.Lutje, V.Kennedy, D.Authié, E.Boulange, A.F.Logan-Henfrey, L.L.Gichuki, B.Gettinby, G.[Trypanosoma congolense: B-Lymphocyte responses differ between trypanotolerant and trypanosusceptible cattle]Trypanosoma congolense: B-Lymphocyte responses differ between trypanotolerant and trypanosusceptible cattle

Sequential changes in the blood and bone marrow (BM) were studied by light and transmission electron microscopy in three Boran and three Ndama cattle before and after a primary infection with Trypanosoma congolense IL 1180. Parasitaemia was essentially similar in the Borans and the Ndamas between...


Anosa, V.O.Logan-Henfrey, L.L.Wells, C.W.[Bone marrow and macrophage functions as determinants of bovine trypanotolerance]Bone marrow and macrophage functions as determinants of bovine trypanotolerance

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