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Anosa, V.O.Logan-Henfrey, L.L.Shaw, M.K.[A light and electron microscopic study of changes in blood and bone marrow in acute hemorrhagic Trypanosoma vivax infection in calves]A light and electron microscopic study of changes in blood and bone marrow in acute hemorrhagic Trypanosoma vivax infection in calves
Williams, D.J.L.Logan-Henfrey, L.L.Authié, E.Seely, C.McOdimba, F.A.[Experimental infection with a haemorrhage-causing Trypanosoma vivax in N'Dama and Boran cattle]Experimental infection with a haemorrhage-causing Trypanosoma vivax in N'Dama and Boran cattle

Using in vitro clonogenic assays, the changes in haemopoietic progenitor cell levels were compared in the bone marrow of three adult trypanotolerant N'Dama cattle and three age-matched trypanosusceptible Boran cattle over 17 weeks (119 days) of a primary Trypanosoma congolense (clone IL 1180) inf...


Andrianarivo, A.G.Muiya, P.Opollo, M.Logan-Henfrey, L.L.[Trypanosoma congolense: Comparative effects of a primary infection on bone marrow progenitor cells from N'Dama and Boran cattle]Trypanosoma congolense: Comparative effects of a primary infection on bone marrow progenitor cells from N'Dama and Boran cattle

The cDNA coding for the soluble form of bovine stem cell factor (boSCF-Ala-105) was cloned and recombinant protein was produced in bacteria as a histidine tagged-protein. The protein was purified from the inclusion bodies in one step by metal chelation chromatography under denaturing conditions. ...


Mertens, B.Muriuki, C.Muiya, P.Andrianarivo, A.Mwangi, S.Logan-Henfrey, L.L.[Bovine stem cell factor: Production of a biologically active protein and mRNA analysis in cattle infected with Trypanosoma congolense]Bovine stem cell factor: Production of a biologically active protein and mRNA analysis in cattle infected with Trypanosoma congolense

Changes in plasma iron and zinc concentration were studied in rabbits following a needle challenge with Trypanosoma brucei brucei clone ILTat 2.1. The infection resulted in a decrease of the concentration of both trace elements. Plasma iron concentrations decreased gradually and were decreased ma...


Mwangi, S.M.McOdimba, F.A.Logan-Henfrey, L.L.[The effect of Trypanosoma brucei brucei infection on rabbit plasma iron and zinc concentrations]The effect of Trypanosoma brucei brucei infection on rabbit plasma iron and zinc concentrations

A bobine cDNA encoding erythropoietin (Epo) was isolated by polymerase chain reaction (PCR) amplification and screening of a bovine kidney cDNA library. The sequenced cDNA has a length of 1312 bp and an open reading frame that encodes a predicted 192-amino-acid (aa) protein, including a putative ...


Suliman, H.B.Majiwa, P.A.O.Feldman, B.F.Mertens, B.Logan-Henfrey, L.L.[Cloning of a cDNA encoding bovine erythropoietin and analysis of its transcription in selected tissues]Cloning of a cDNA encoding bovine erythropoietin and analysis of its transcription in selected tissues
Sileghem, M.R.Flynn, J.N.Logan-Henfrey, L.L.Ellis, J.[Tumour necrosis factor production by monocytes from cattle infected with Trypanosoma (Duttonella) vivax and Trypanosoma (Nannomonas) congolense STI possible association with severity of anaemia associated with the disease]Tumour necrosis factor production by monocytes from cattle infected with Trypanosoma (Duttonella) vivax and Trypanosoma (Nannomonas) congolense STI possible association with severity of anaemia associated with the disease

Acute Trypanosoma congolense infection induced moderate, transient anemia in N'Dama cattle (trypanotolerant) and severe anemia in Boran cattle (trypanosusceptible). Erythropoietin receptor (EpoR) was cloned and sequenced from the two breeds of cattle. A single position mutation of Tyr in the Bora...


Suliman, H.B.Logan-Henfrey, L.L.Majiwa, P.A.O.Ole-MoiYoi, O.K.Feldman, B.F.[Analysis of erythropoietin and erythropoietin receptor genes expression in cattle during acute infection with Trypanosoma congolense]Analysis of erythropoietin and erythropoietin receptor genes expression in cattle during acute infection with Trypanosoma congolense

N'Dama (Bos taurus) cattle are known to tolerate trypanosome infections, developing less severe anemia and lower parasitemia, compared to Boran (Bos indicus) cattle. Young calves were also reported to be more resistant to trypanosomiasis than adult cattle. To expore the basis for this resistance,...


Andrianarivo, A.G.Muiya, P.Logan-Henfrey, L.L.[Trypanosoma congolense: High erythropoietic potential in infected yearling cattle during the acute phase of the anemia]Trypanosoma congolense: High erythropoietic potential in infected yearling cattle during the acute phase of the anemia

Trypanosomiasis is a serious constraint to livestock production in sub-Saharan Africa. Some breeds of cattle are genetically more resistant to the pathogenic effects of trypanosome infection. We measured B-cell activation and the quantity and isotype of antibody produced at the cellular level in ...


Taylor, K.A.Lutje, V.Kennedy, D.Authié, E.Boulange, A.F.Logan-Henfrey, L.L.Gichuki, B.Gettinby, G.[Trypanosoma congolense: B-Lymphocyte responses differ between trypanotolerant and trypanosusceptible cattle]Trypanosoma congolense: B-Lymphocyte responses differ between trypanotolerant and trypanosusceptible cattle

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