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Acute Trypanosoma congolense infection induced moderate, transient anemia in N'Dama cattle (trypanotolerant) and severe anemia in Boran cattle (trypanosusceptible). Erythropoietin receptor (EpoR) was cloned and sequenced from the two breeds of cattle. A single position mutation of Tyr in the Bora...


Suliman, H.B.Logan-Henfrey, L.L.Majiwa, P.A.O.Ole-MoiYoi, O.K.Feldman, B.F.[Analysis of erythropoietin and erythropoietin receptor genes expression in cattle during acute infection with Trypanosoma congolense]Analysis of erythropoietin and erythropoietin receptor genes expression in cattle during acute infection with Trypanosoma congolense

N'Dama (Bos taurus) cattle are known to tolerate trypanosome infections, developing less severe anemia and lower parasitemia, compared to Boran (Bos indicus) cattle. Young calves were also reported to be more resistant to trypanosomiasis than adult cattle. To expore the basis for this resistance,...


Andrianarivo, A.G.Muiya, P.Logan-Henfrey, L.L.[Trypanosoma congolense: High erythropoietic potential in infected yearling cattle during the acute phase of the anemia]Trypanosoma congolense: High erythropoietic potential in infected yearling cattle during the acute phase of the anemia

Trypanosomiasis is a serious constraint to livestock production in sub-Saharan Africa. Some breeds of cattle are genetically more resistant to the pathogenic effects of trypanosome infection. We measured B-cell activation and the quantity and isotype of antibody produced at the cellular level in ...


Taylor, K.A.Lutje, V.Kennedy, D.Authié, E.Boulange, A.F.Logan-Henfrey, L.L.Gichuki, B.Gettinby, G.[Trypanosoma congolense: B-Lymphocyte responses differ between trypanotolerant and trypanosusceptible cattle]Trypanosoma congolense: B-Lymphocyte responses differ between trypanotolerant and trypanosusceptible cattle

Sequential changes in the blood and bone marrow (BM) were studied by light and transmission electron microscopy in three Boran and three Ndama cattle before and after a primary infection with Trypanosoma congolense IL 1180. Parasitaemia was essentially similar in the Borans and the Ndamas between...


Anosa, V.O.Logan-Henfrey, L.L.Wells, C.W.[Bone marrow and macrophage functions as determinants of bovine trypanotolerance]Bone marrow and macrophage functions as determinants of bovine trypanotolerance

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