Memory T- and B-cell responses to trypanosome antigens were measured in peripheral blood mononuclear cells, spleen and lymph node cells obtained from 4 trypanotolerant N'Dama cattle which had been exposed to 6 experimental infections with Trypanosoma congolense. These cattle were treated with try...
Lutje, V.
,
Taylor, K.A.
,
Boulange, A.F.
,
Authié, E.
,
[Trypanosoma congolense: Tissue distribution of long-term T- and B-cell responses in cattle]
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Trypanosoma congolense: Tissue distribution of long-term T- and B-cell responses in cattle
T-cell-mediated immune responses to defined antigens of Trypanosoma congolense were measured in cattle undergoing primary infection. The antigens used were the variable surface glycoprotein and two invariant antigens, a 33-kDa cysteine protease (congopain) and a recombinant form of a 69-kDa heat-...
Lutje, V.
,
Mertens, B.
,
Boulange, A.F.
,
Williams, D.J.L.
,
Authié, E.
,
[Trypanosoma congolense: Proliferative responses and interleukin production in lymph node cells of infected cattle]
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Trypanosoma congolense: Proliferative responses and interleukin production in lymph node cells of infected cattle
Infections of cattle with tsetse-transmitted Trypanosoma congolense are accompanied by antibody responses to the variable surface glycoprotein (VSG) and to two major invariant antigens, a member of the hsp 70 family and a 33KDa cysteine protease. During primary infection, trypanotolerant N'Dama (...
Lutje, V.
,
Authié, E.
,
Boulange, A.F.
,
Williams, D.J.L.
,
[Bovine T-cell responses to defined Trypanosoma congolense antigens during infection]
,
Bovine T-cell responses to defined Trypanosoma congolense antigens during infection
Analysis of serum antibody responses in cattle experimentally infected with Trypanosoma congolense suggested that antibody responses of trypanosusceptible Boran cattle are less efficient in isotype switching and affinity maturation than those of trypanotolerant N'Dama cattle. High levels of polys...