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Mycoplasmas are the smallest free-living organisms and cause a number of economically important diseases affecting humans, animals, insects, and plants. Here, we demonstrate that highly virulent Mycoplasma mycoides subspecies capri (Mmc) can be fully attenuated via targeted deletion of non-essent...


Jores, JoergMa, L.Ssajjakambwe, PaulSchieck, Elise G.Liljander, Anne M.Chandran, S.Stoffel, M.H.Cippa, V.Arfi, Y.Assad-Garcia, N.Falquet, L.Sirand-Pugnet, P.Blanchard, AlainLartigue, C.Posthaus, H.Labroussaa, F.Vashee, S.[Removal of a subset of non-essential genes fully attenuates a highly virulent Mycoplasma strain]Removal of a subset of non-essential genes fully attenuates a highly virulent Mycoplasma strain
Ma, L.Derner, J.D.Harmel, D.Tartako, J.Moore, A.D.Rotz, A.Augustine, D.J.Boone, Randall B.Coughenour, M.B.Beukes, P.C.Wijk, Mark T. vanBellocchi, G.Cullen, B.R.Wilme, H.[Application of grazing land models in ecosystem management: Current status and next frontiers]Application of grazing land models in ecosystem management: Current status and next frontiers

With the development of several new technologies using synthetic biology, it is possible to engineer genetically intractable organisms including Mycoplasma mycoides subspecies capri (Mmc), by cloning the intact bacterial genome in yeast, using the host yeast’s genetic tools to modify the cloned g...


Chandran, S.Noskov, V.N.Segall-Shapiro, T.H.Ma, L.Whiteis, C.Lartigue, C.Jores, JoergVashee, S.Ray-Yuan Chuang[TREC-IN: gene knock-in genetic tool for genomes cloned in yeast]TREC-IN: gene knock-in genetic tool for genomes cloned in yeast

Background: Cha-hua (Camellia reticulata) is one of China’s traditional ornamental flowers developed by the local people of Yunnan Province. Today, more than 500 cultivars and hybrids are recognized. Many ancient camellia trees still survive and are managed by local peopl. A few records on cha-hu...


Xin, T.Riek, J. deGuo, H.Jarvis, D.Ma, L.Long, C.[Impact of traditional culture on Camellia reticulata in Yunnan, China]Impact of traditional culture on Camellia reticulata in Yunnan, China

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