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Journal Article 2016-07-15

Autor: Hemmink, J.D. Weir, W. MacHugh, Niall D. Graham, S.P. Patel, Ekta Paxton, E. Shiels, B. Toye, Philip G. Morrison, W. Ivan Pelle, Roger

An infection and treatment protocol is used to vaccinate cattle against Theileria parva infection. Due to incomplete cross-protection between different parasite isolates, a mixture of three isolates, termed the Muguga cocktail, is used for vaccination. While vaccination of cattle in some regions ...

Enlace original: https://cgspace.cgiar.org/handle/10568/73303

Investigación en Agricultura
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Hemmink, J.D. ,  Weir, W. ,  MacHugh, Niall D. ,  Graham, S.P. ,  Patel, Ekta ,  Paxton, E. ,  Shiels, B. ,  Toye, Philip G. ,  Morrison, W. Ivan ,  Pelle, Roger ,  [Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva] ,  Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva
Journal Article 1992

Autor: Naessens, Jan Sileghem, M.R. MacHugh, Niall D. Park, Y.H. Davis, W.C. Toye, Philip G.
Enlace original: https://cgspace.cgiar.org/handle/10568/28710

Investigación en Agricultura
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Naessens, Jan ,  Sileghem, M.R. ,  MacHugh, Niall D. ,  Park, Y.H. ,  Davis, W.C. ,  Toye, Philip G. ,  [Selection of BoCD25 monoclonal antibodies by screening mouse L cells transfected with the bovine p55-interleukin-2 (IL-2) receptor gene] ,  Selection of BoCD25 monoclonal antibodies by screening mouse L cells transfected with the bovine p55-interleukin-2 (IL-2) receptor gene
Journal Article 1989

Autor: Bensaid, A.M. Kaushal, A. MacHugh, Niall D. Shapiro, S.Z. Teale, A.J.
Enlace original: https://cgspace.cgiar.org/handle/10568/28234

Investigación en Agricultura
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Bensaid, A.M. ,  Kaushal, A. ,  MacHugh, Niall D. ,  Shapiro, S.Z. ,  Teale, A.J. ,  [Biochemical characterization of activation associated bovine class I major histocompatibility complex antigens] ,  Biochemical characterization of activation associated bovine class I major histocompatibility complex antigens
Journal Article 1988

Autor: Emery, D.L. MacHugh, Niall D. Morrison, W. Ivan
Enlace original: https://cgspace.cgiar.org/handle/10568/29349

Investigación en Agricultura
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Emery, D.L. ,  MacHugh, Niall D. ,  Morrison, W. Ivan ,  [Theileria parva (Muguga) infects bovine T-lymphocytes in vivo and induces coexpression of BoT4 and BoT8] ,  Theileria parva (Muguga) infects bovine T-lymphocytes in vivo and induces coexpression of BoT4 and BoT8
Journal Article 1987

Autor: Ellis, J.A. Scott, J.R. MacHugh, Niall D. Gettinby, G. Davis, W.C.
Enlace original: https://cgspace.cgiar.org/handle/10568/29359

Investigación en Agricultura
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Ellis, J.A. ,  Scott, J.R. ,  MacHugh, Niall D. ,  Gettinby, G. ,  Davis, W.C. ,  [Peripheral blood leukocyte subpopulation dynamics during Trypanosoma congolense infection in Boran and N'Dama cattle. An analysis using monoclonal antibodies and flow cytometry] ,  Peripheral blood leukocyte subpopulation dynamics during Trypanosoma congolense infection in Boran and N'Dama cattle. An analysis using monoclonal antibodies and flow cytometry
Journal Article 1996

Autor: Totte, P. Vachiery, N. Martínez, D. Trap, I. Ballingall, K.T. MacHugh, Niall D. Bensaid, A. Werenne, J.

Recombinant bovine IFN gamma is a potent inhibitor of Cowdria ruminantium growth in vitro irrespective of the rickettsial stock, or the origin of the endothelial cells. These results suggest an important role for IFN gamma in protective immune responses against C. ruminantium infections. Here we ...

Enlace original: https://cgspace.cgiar.org/handle/10568/29855

Investigación en Agricultura
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Totte, P. ,  Vachiery, N. ,  Martínez, D. ,  Trap, I. ,  Ballingall, K.T. ,  MacHugh, Niall D. ,  Bensaid, A. ,  Werenne, J. ,  [Recombinant bovine interferon gamma inhibits the growth of Cowdria ruminantium but fails to induce major histocompatibility complex class II following infection of endothelial cells] ,  Recombinant bovine interferon gamma inhibits the growth of Cowdria ruminantium but fails to induce major histocompatibility complex class II following infection of endothelial cells
Journal Article 2001

Autor: Ballingall, K.T. MacHugh, Niall D. Taracha, E.L.N. Mertens, B. McKeever, B.D.

Dendritic cells (DC) constitute the most effective immune cell population for priming and recalling T cell responses to foreign antigens. DC patrol the peripheral tissues collecting foreign antigen for subsequent presentation by classical class II MHC molecules to T cells in the draining lymph no...

Enlace original: https://cgspace.cgiar.org/handle/10568/32905

Investigación en Agricultura
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Ballingall, K.T. ,  MacHugh, Niall D. ,  Taracha, E.L.N. ,  Mertens, B. ,  McKeever, B.D. ,  [Transcription of the unique ruminant class II major histocompatibility complex-DYA and DIB genes in dendritic cells] ,  Transcription of the unique ruminant class II major histocompatibility complex-DYA and DIB genes in dendritic cells
Journal Article 1999

Autor: Ellis, S.A. Holmes, E.C. Staines, K.A. Smith, K.B. Stear, M.J. McKeever, Declan J. MacHugh, Niall D. Morrison, W. Ivan

Analysis of cattle major histocompatibility complex (MHC) (BoLA) class I gene expression using serological and biochemical methods has demonstrated a high level of polymorphism. However, analysis of class I cDNA sequences has failed to produce conclusive evidence concerning the number and nature ...

Enlace original: https://cgspace.cgiar.org/handle/10568/32939

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Ellis, S.A. ,  Holmes, E.C. ,  Staines, K.A. ,  Smith, K.B. ,  Stear, M.J. ,  McKeever, Declan J. ,  MacHugh, Niall D. ,  Morrison, W. Ivan ,  [Variation in the number of expressed MHC genes in different cattle class I haplotypes] ,  Variation in the number of expressed MHC genes in different cattle class I haplotypes
Journal Article 2001

Autor: Ballingall, K.T. Waibochi, L. Homes, E.C. Woelk, C.H. MacHugh, Niall D. Lutje, V. McKeever, Declan J.

Cattle in Africa are a genetically diverse population that has resulted from successive introduction of Asian Bos indicus and European B. Taurus cattle. However, analysis of mitochondrial genetic diversity in African cattle identified three lineages, one associated with Asian B. indicus, one with...

Enlace original: https://cgspace.cgiar.org/handle/10568/32940

Investigación en Agricultura
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Ballingall, K.T. ,  Waibochi, L. ,  Homes, E.C. ,  Woelk, C.H. ,  MacHugh, Niall D. ,  Lutje, V. ,  McKeever, Declan J. ,  [The CD45 locus in cattle: Allelic polymorphism and evidence for exceptional positive natural selection] ,  The CD45 locus in cattle: Allelic polymorphism and evidence for exceptional positive natural selection
Journal Article 2009-09-15

Autor: MacHugh, Niall D. Connelley, T. Graham, S.P. Pelle, Roger Formisano, P. Taracha, E.L.N. Ellis, S.A. McKeever, Declan J. Burrells, A. Morrison, W. Ivan

Although immunodominance of CD8+ T-cell responses is a well-recognised feature of viral infections, its role in responses to more antigenically complex pathogens is less clear. In previous studies we have observed that CD8+ T-cell responses to Theileria parva exhibit different patterns of parasit...

Enlace original: https://cgspace.cgiar.org/handle/10568/342

Investigación en Agricultura
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MacHugh, Niall D. ,  Connelley, T. ,  Graham, S.P. ,  Pelle, Roger ,  Formisano, P. ,  Taracha, E.L.N. ,  Ellis, S.A. ,  McKeever, Declan J. ,  Burrells, A. ,  Morrison, W. Ivan ,  [CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity] ,  CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity

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