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Emery, D.L.MacHugh, Niall D.Morrison, W. Ivan[Theileria parva (Muguga) infects bovine T-lymphocytes in vivo and induces coexpression of BoT4 and BoT8]Theileria parva (Muguga) infects bovine T-lymphocytes in vivo and induces coexpression of BoT4 and BoT8
Ellis, J.A.Scott, J.R.MacHugh, Niall D.Gettinby, G.Davis, W.C.[Peripheral blood leukocyte subpopulation dynamics during Trypanosoma congolense infection in Boran and N'Dama cattle. An analysis using monoclonal antibodies and flow cytometry]Peripheral blood leukocyte subpopulation dynamics during Trypanosoma congolense infection in Boran and N'Dama cattle. An analysis using monoclonal antibodies and flow cytometry
Morrison, W. IvanMacHugh, Niall D.Bensaid, A.M.Goddeeris, B.M.Teale, A.J.McKeever, Declan J.[A monoclonal antibody which reacts specifically with a population of bovine lymphocytes lacking B cell and T cell markers]A monoclonal antibody which reacts specifically with a population of bovine lymphocytes lacking B cell and T cell markers

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated through the destruction of parasite infected lymphocytes by MHC class I restricted CD8+ CTL. Six parasite proteins targeted by CTL from T. parva immune cattle have been identified and raised...


Graham, S.P.Pelle, RogerVilliers, Etienne P. deYamage, M.Mwangi, D.M.Honda, Y.Ellis, S.A.MacHugh, Niall D.Morrison, W. IvanTaracha, E.L.N.[Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva]Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva

Species: RuminantsTheileria parva is an intracellular protozoal parasite which causes East Coast Fever (ECF), a major constraint to cattle production in eastern and southern Africa. Characteristics of the protective CD8+ T-cell response against T. parva suggest it is focused on a limited number o...


Connelley, T.MacHugh, Niall D.Graham, S.Taracha, E.A.Burrells, A.Ngugi, D.Morrison, W. Ivan[The bovine CD8+ T-cell response to Theileria parva displays epitope immunodominance and oligoclonality]The bovine CD8+ T-cell response to Theileria parva displays epitope immunodominance and oligoclonality
Davis, W.C.Ellis, J.A.MacHugh, Niall D.Baldwin, C.L.[Bovine pan T-cell monoclonal antibodies reactive with a molecule similar to CD2]Bovine pan T-cell monoclonal antibodies reactive with a molecule similar to CD2
Pepin, L.Winjgaard, P.Lehrun, D.MacHugh, Niall D.Teale, A.J.Maillard, J.C.Clevers, H.Bensaid, A.M.[Description of a new bovine multigene family encoding for markers of differentiation of y/d T-cells]Description of a new bovine multigene family encoding for markers of differentiation of y/d T-cells
Clevers, H.C.MacHugh, Niall D.Bensaid, A.Dunlap, S.Baldwin, C.L.Kaushal, A.Iams, K.P.Howard, C.J.Morrison, W. Ivan[Identification of a bovine surface antigen uniquely expressed on CD4/CD8 negative TCR-gamma/delta positive T lymphocytes]Identification of a bovine surface antigen uniquely expressed on CD4/CD8 negative TCR-gamma/delta positive T lymphocytes
Martini, J.C. deMacHugh, Niall D.Naessens, JanTeale, A.J.[Differential in vitro and in vivo expression of MHC class II antigens in bovine lymphocytes infected by Theileria parva]Differential in vitro and in vivo expression of MHC class II antigens in bovine lymphocytes infected by Theileria parva

The studies reported here describe methodology permiting the direct identification of antigens recognized by cytotoxic T lymphocytes. We demonstrated that bovine alloreactive CTL can detect a bovine MHC molecule transiently expressed in a COS cell population in a standard microcytotoxicity assay....


Toye, Philip G.Wijngaard, P.L.J.MacHugh, Niall D.Clevers, H.[An assay for the identification of antigens recognized by cytotoxic T cells, based on the transient transfection of COS cells]An assay for the identification of antigens recognized by cytotoxic T cells, based on the transient transfection of COS cells

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