Six new cyclodiprenyl phenols were synthesized by direct coupling of perillyl alcohol and the appropriate phenol. Their structures were established by IR, HRMS and mainly NMR. Three human cancer cell lines-breast (MCF-7), prostate (PC-3) and colon (HT-29)-were used in antiproliferative assays, wi...
Said, B.
,
Montenegro, I.
,
Valenzuela, M.
,
Olguín, Y.
,
Caro, N.
,
Werner, E.
,
Godoy, P.
,
Villena, J.
,
Madrid, A.
,
[Synthesis and antiproliferative activity of new cyclodiprenyl phenols against select cancer cell lines]
,
Synthesis and antiproliferative activity of new cyclodiprenyl phenols against select cancer cell lines
Tomato crops can be affected by several infectious diseases produced by bacteria, fungi, and oomycetes. Four phytopathogens are of special concern because of the major economic losses they generate worldwide in tomato production; Clavibacter michiganensis subsp. michiganensis and Pseudomonas syri...
Montenegro, I.
,
Madrid, A.
,
Cuellar, M.
,
Seeger, M.
,
Alfaro, J.F.
,
Besoain, X.
,
Martínez, J.P.
,
Ramirez, I.
,
Olguín, Y.
,
Valenzuela, M.
,
[Biopesticide activity from drimanic compounds to control tomato pathogens]
,
Biopesticide activity from drimanic compounds to control tomato pathogens
Advances in the generation of suitable thermosensitive hydrogels for the delivery of cells in neural tissue engineering demonstrate a delicate relationship between physical properties and capabilities to promote cell proliferation and differentiation. To improve the properties of these materials,...
Olguín, Y.
,
Campos, C.
,
Catalán, J.
,
Velásquez, L.
,
Osorio, F.
,
Montenegro, I.
,
Madrid, A.
,
Acevedo, C.
,
[Effects of Liposomes Contained in Thermosensitive Hydrogels as Biomaterials Useful in Neural Tissue Engineering]
,
Effects of Liposomes Contained in Thermosensitive Hydrogels as Biomaterials Useful in Neural Tissue Engineering
An efficient synthesis of a series of 4-oxyalkyl-isocordoin analogues (2–8) is reported for the first time. Their structures were confirmed by1H-NMR,13C-NMR, and HRMS. Their anti-oomycete activity was evaluated by mycelium and spores inhibition assay against two selected pathogenic oomycetes stra...
Escobar, B.
,
Montenegro, I.
,
Villena, J.
,
Werner, E.
,
Godoy, P.
,
Olguín, Y.
,
Madrid, A.
,
[Hemi-Synthesis and Anti-Oomycete Activity of Analogues of Isocordoin]
,
Hemi-Synthesis and Anti-Oomycete Activity of Analogues of Isocordoin