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Understanding the basis of protective immunity to Cowdria ruminantium will facilitate the development of an effective subunit vaccine against heartwater in ruminants and contribute to a better definition of protective immune mechanisms to obligate intracellular pathogens in general. Until recentl...


Totte, P.Bensaid, A.Mahan, S.M.Martínez, D.McKeever, Declan J.[Immune responses to Cowdria ruminantium infections]Immune responses to Cowdria ruminantium infections
Mahan, S.M.Hendershot, L.Black, S.J.[Control of trypanodestructive antibody responses and parasitemia in mice infected with Trypanosoma (Duttonella) vivax]Control of trypanodestructive antibody responses and parasitemia in mice infected with Trypanosoma (Duttonella) vivax

The response of peripheral blood mononuclear cells (PBMC) collected from cattle immunized with killed C. ruminantium to MAP1, MAP1-B, MAP2 and to a lysate of Cowdria was characterized in vitro. CD4+ T lymphocytes responded strongly to Cowdria lysates while B cells and gamma delta T cells prolifer...


Totte, P.McKeever, Declan J.Jongejan, F.Barbet, A.Mahan, S.M.Mwangi, D.Bensaid, A.[Analysis of cellular responses to native and recombinant proteins of Cowdria ruminantium]Analysis of cellular responses to native and recombinant proteins of Cowdria ruminantium

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