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Journal Article 1999

Autor: Peter, T.F. Perry, Brian D. O'Callaghan, C.J. Medley, G.F. Mlambo, G. Barbet, A.F. Mahan, S.M.

Analysis of the transmission dynamics of Cowdria ruminantium, the tick-borne rickettsial agent of heartwater in ruminants, requires accurate measures of infection in vector populations. To obtain these, Amblyomma hebraeum ticks were collected at two heartwater-endemic locations in the lowveld and...

Enlace original: https://cgspace.cgiar.org/handle/10568/28497

Investigación en Agricultura
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Peter, T.F. ,  Perry, Brian D. ,  O'Callaghan, C.J. ,  Medley, G.F. ,  Mlambo, G. ,  Barbet, A.F. ,  Mahan, S.M. ,  [Prevalence of Cowdria ruminantium infection in Amblyomma hebraeum ticks from heartwater-endemic areas of Zimbabwe] ,  Prevalence of Cowdria ruminantium infection in Amblyomma hebraeum ticks from heartwater-endemic areas of Zimbabwe
Journal Article 1998

Autor: Mwangi, D.M. Mahan, S.M. Nyanjui, J.K. Taracha, E.L.N. McKeever, Declan J.

Peripheral blood mononuclear cells (PBMC) from immune cattle proliferate in the presence of autologous Cowdria ruminantium-infected endothelial cells and monocytes. Endothelial cells required treatment with T-cell growth factors to induce class II major histocompatibility complex expression prior...

Enlace original: https://cgspace.cgiar.org/handle/10568/28756

Investigación en Agricultura
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Mwangi, D.M. ,  Mahan, S.M. ,  Nyanjui, J.K. ,  Taracha, E.L.N. ,  McKeever, Declan J. ,  [Immunization of cattle by infection with Cowdria ruminantium elicits T lymphocytes that recognize autologous, infected endothelial cells and monocytes] ,  Immunization of cattle by infection with Cowdria ruminantium elicits T lymphocytes that recognize autologous, infected endothelial cells and monocytes
Journal Article 1999

Autor: Chamboko, Tafireyi Mukhebi, A.W. O'Callaghan, C.J. Peter, T.F. Kruska, R.L. Medley, G.F. Mahan, S.M. Perry, Brian D.

In order to assess the economic impact of heartwater (Cowdria ruminantium infection) and model the impact of improved vaccines against the disease, a field study was conducted to provide data on livestock productivity indicators in Zimbabwe. Cross-sectional studies were performed in the two main ...

Enlace original: https://cgspace.cgiar.org/handle/10568/29589

Investigación en Agricultura
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Chamboko, Tafireyi ,  Mukhebi, A.W. ,  O'Callaghan, C.J. ,  Peter, T.F. ,  Kruska, R.L. ,  Medley, G.F. ,  Mahan, S.M. ,  Perry, Brian D. ,  [Heartwater and the economics of livestock production on large scale commercial and smallholder farms in Zimbabwe] ,  Heartwater and the economics of livestock production on large scale commercial and smallholder farms in Zimbabwe
Journal Article 1998

Autor: Peter, T.F. Perry, Brian D. O'Callaghan, C.J. Medley, G.F. Shumba, W. Madzima, W. Burridge, M.J. Mahan, S.M.

The tick vectors of heartwater (Cowdria ruminantium infection) in Zimbabwe, Amblyomma hebraeum and Amblyomma variegatum, historically were believed to be confined to the low-lying regions of the south and north-west of the country. However, country-wide surveys performed in 1975-1980 and 1988-199...

Enlace original: https://cgspace.cgiar.org/handle/10568/32908

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Peter, T.F. ,  Perry, Brian D. ,  O'Callaghan, C.J. ,  Medley, G.F. ,  Shumba, W. ,  Madzima, W. ,  Burridge, M.J. ,  Mahan, S.M. ,  [Distributions of the vectors of heartwater, Amblyomma hebraeum and amblyomma variegatum (Acari: Ixodidae), in Zimbabwe] ,  Distributions of the vectors of heartwater, Amblyomma hebraeum and amblyomma variegatum (Acari: Ixodidae), in Zimbabwe
Conference Paper 2000

Autor: O'Callaghan, C.J. Medley, G.F. Peter, T.F. Mahan, S.M. Perry, Brian D.

Heartwater, an infectious disease of ruminants caused by the rickettsia Cowdria ruminantium (transmitted by ixodid ticks of the genus Amblyomma and vertically), severely constrains livestock production throughout sub-Saharan Africa. Its epidemiology varies from epidemics with high mortality (on i...

Enlace original: https://cgspace.cgiar.org/handle/10568/50957

Investigación en Agricultura
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O'Callaghan, C.J. ,  Medley, G.F. ,  Peter, T.F. ,  Mahan, S.M. ,  Perry, Brian D. ,  [Predicting the effect of vaccination of the transmission dynamics of heartwater (Cowdria ruminantium infection)] ,  Predicting the effect of vaccination of the transmission dynamics of heartwater (Cowdria ruminantium infection)
Conference Paper 1998

Autor: Mahan, S.M. Sileghem, M.R. Smith, G. Byrom, B.

Immune mechanisms against Cowdria ruminantium infection in livestock hosts are being investigated. This knowledge will be important for identification of protective antigens of C. ruminantium which will have application in the Development of vaccines against heartwater. T-cell Con-A supernatants ...

Enlace original: https://cgspace.cgiar.org/handle/10568/51046

Investigación en Agricultura
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Mahan, S.M. ,  Sileghem, M.R. ,  Smith, G. ,  Byrom, B. ,  [Role of interferon gamma in control of Cowdria ruminantium growth in-vitro. Abstract] ,  Role of interferon gamma in control of Cowdria ruminantium growth in-vitro. Abstract
Conference Paper 2000

Autor: Peter, T.F. O'Callaghan, C.J. Medley, G.F. Mahan, S.M. Perry, Brian D.

Heartwater is a disease of high mortality in domestic ruminants (cattle, sheep and goats) in sub-Saharan Africa and in the Caribbean. An intracellular rickettsia, Cowdria ruminantium, is the cause of the disease and is transmitted by ticks of the genus Amblyomma. Losses due to heartwater are high...

Enlace original: https://cgspace.cgiar.org/handle/10568/50223

Investigación en Agricultura
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Peter, T.F. ,  O'Callaghan, C.J. ,  Medley, G.F. ,  Mahan, S.M. ,  Perry, Brian D. ,  [Biological support for modeling the transmission dynamics of cowdriosis] ,  Biological support for modeling the transmission dynamics of cowdriosis
Conference Paper 2000

Autor: Minjauw, B. Kruska, R.L. Odero, A. Randolph, Thomas F. McDermott, John J. Mahan, S.M. Perry, Brian D.

Heartwater is a tick-borne disease of cattle, sheep and goats and some wild ruminants prevalent in much of Africa and the Caribbean. It is caused by the rickettsial organism Cowdria ruminantium and transmitted by ticks of the genus Amblyomma. The disease has traditionally been controlled by the u...

Enlace original: https://cgspace.cgiar.org/handle/10568/50419

Investigación en Agricultura
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Minjauw, B. ,  Kruska, R.L. ,  Odero, A. ,  Randolph, Thomas F. ,  McDermott, John J. ,  Mahan, S.M. ,  Perry, Brian D. ,  [Economic impact assessment of Cowdria ruminantium infection and its control in Southern Africa] ,  Economic impact assessment of Cowdria ruminantium infection and its control in Southern Africa
Journal Article 1998

Autor: Totte, P. McKeever, Declan J. Jongejan, F. Barbet, A. Mahan, S.M. Mwangi, D. Bensaid, A.

The response of peripheral blood mononuclear cells (PBMC) collected from cattle immunized with killed C. ruminantium to MAP1, MAP1-B, MAP2 and to a lysate of Cowdria was characterized in vitro. CD4+ T lymphocytes responded strongly to Cowdria lysates while B cells and gamma delta T cells prolifer...

Enlace original: https://cgspace.cgiar.org/handle/10568/33077

Investigación en Agricultura
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Totte, P. ,  McKeever, Declan J. ,  Jongejan, F. ,  Barbet, A. ,  Mahan, S.M. ,  Mwangi, D. ,  Bensaid, A. ,  [Analysis of cellular responses to native and recombinant proteins of Cowdria ruminantium] ,  Analysis of cellular responses to native and recombinant proteins of Cowdria ruminantium
Journal Article 1998

Autor: Mwangi, D.M. McKeever, Declan J. Nyanjui, J.K. Barbet, A.F. Mahan, S.M.

Heartwater (cowdriosis) is an infectious disease of domestic ruminants in Africa and the Carribean and is caused by a tick-borne intracellular rickettsial agent, Cowdria ruminantium. There is growing evidence that immunity of cattle to the disease is medicated by T. lymphocytes. Antigens that sti...

Enlace original: https://cgspace.cgiar.org/handle/10568/33078

Investigación en Agricultura
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Mwangi, D.M. ,  McKeever, Declan J. ,  Nyanjui, J.K. ,  Barbet, A.F. ,  Mahan, S.M. ,  [Major antigenic proteins 1 and 2 of Cowdria ruminantium are targets for T-lymphocyte responses of immune cattle] ,  Major antigenic proteins 1 and 2 of Cowdria ruminantium are targets for T-lymphocyte responses of immune cattle

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