The tick vectors of heartwater (Cowdria ruminantium infection) in Zimbabwe, Amblyomma hebraeum and Amblyomma variegatum, historically were believed to be confined to the low-lying regions of the south and north-west of the country. However, country-wide surveys performed in 1975-1980 and 1988-199...
Peter, T.F.
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Perry, Brian D.
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O'Callaghan, C.J.
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Medley, G.F.
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Shumba, W.
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Madzima, W.
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Burridge, M.J.
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Mahan, S.M.
,
[Distributions of the vectors of heartwater, Amblyomma hebraeum and amblyomma variegatum (Acari: Ixodidae), in Zimbabwe]
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Distributions of the vectors of heartwater, Amblyomma hebraeum and amblyomma variegatum (Acari: Ixodidae), in Zimbabwe
The response of peripheral blood mononuclear cells (PBMC) collected from cattle immunized with killed C. ruminantium to MAP1, MAP1-B, MAP2 and to a lysate of Cowdria was characterized in vitro. CD4+ T lymphocytes responded strongly to Cowdria lysates while B cells and gamma delta T cells prolifer...
Totte, P.
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McKeever, Declan J.
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Jongejan, F.
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Barbet, A.
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Mahan, S.M.
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Mwangi, D.
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Bensaid, A.
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[Analysis of cellular responses to native and recombinant proteins of Cowdria ruminantium]
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Analysis of cellular responses to native and recombinant proteins of Cowdria ruminantium
Heartwater (cowdriosis) is an infectious disease of domestic ruminants in Africa and the Carribean and is caused by a tick-borne intracellular rickettsial agent, Cowdria ruminantium. There is growing evidence that immunity of cattle to the disease is medicated by T. lymphocytes. Antigens that sti...
Mwangi, D.M.
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McKeever, Declan J.
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Nyanjui, J.K.
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Barbet, A.F.
,
Mahan, S.M.
,
[Major antigenic proteins 1 and 2 of Cowdria ruminantium are targets for T-lymphocyte responses of immune cattle]
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Major antigenic proteins 1 and 2 of Cowdria ruminantium are targets for T-lymphocyte responses of immune cattle