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There is growing evidence that immunity of cattle to Cowdria ruminantium infection is mediated by T lymphocytes. C. ruminantium antigens that stimulate these responses are therefore of considerable importance to the development of a sub-unit vaccine against the disease. We have examined T cell re...


Mwangi, D.M.McKeever, Declan J.Nyanjui, J.K.Barbet, A.F.Mahan, S.M.[Immunisation of cattle against heartwater by infection with Cowdria ruminantium elicits T lymphocytes that recognise major antigenic proteins 1 and 2 of the agent]Immunisation of cattle against heartwater by infection with Cowdria ruminantium elicits T lymphocytes that recognise major antigenic proteins 1 and 2 of the agent

Understanding the basis of protective immunity to Cowdria ruminantium will facilitate the development of an effective subunit vaccine against heartwater in ruminants and contribute to a better definition of protective immune mechanisms to obligate intracellular pathogens in general. Until recentl...


Totte, P.Bensaid, A.Mahan, S.M.Martínez, D.McKeever, Declan J.[Immune responses to Cowdria ruminantium infections]Immune responses to Cowdria ruminantium infections

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