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Experiments were carried out in goats to determine the frequency with which diminazene-resistant trypanosomes occur in parasite populations before and after the intramuscular treatment of the goats with diminazene aceturate. Trypanosoma congolense IL3274, a diminazene-resistant clone, was used to...


Mamman, M.Williams, D.J.L.Murphy, N.B.Peregrine, A.S.[Apparent rarity of diminazene-resistant trypanosomes in goats infected with a diminazene-resistant population of Trypanosoma congolense]Apparent rarity of diminazene-resistant trypanosomes in goats infected with a diminazene-resistant population of Trypanosoma congolense

A study was undertaken to compare the absorption and distribution of the antitrypanosomal drug diminazene aceturate in plasma, cerebrospinal fluid (CSF) and lymph of goats. The study comprised three groups of three goats each. Animals in each group were treated with a single intramuscular dose of...


Mamman, M.McKeever, Declan J.Peregrine, A.S.[Comparative pharmacokinetics of diminazene in plasma, cerebrospinal fluid and lymph of goats]Comparative pharmacokinetics of diminazene in plasma, cerebrospinal fluid and lymph of goats

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