Increased expression of the TRPM4 channel has been reported to be associated with the progression of prostate cancer. However, the molecular mechanism underlying its effect remains unknown. This work found that decreasing TRPM4 levels leads to the reduced proliferation of PC3 cells. This effect w...
Sagredo, A.I.
,
Sagredo, E.A.
,
Cappelli, C.
,
Báez, P.
,
Andaur, R.E.
,
Blanco, C.
,
Tapia, J.C.
,
Echeverría, C.
,
Cerda, O.
,
Stutzin, A.
,
Simon, F.
,
Marcelain, K.
,
Armisén, R.
,
[TRPM4 regulates Akt/GSK3-β activity and enhances β-catenin signaling and cell proliferation in prostate cancer cells]
,
TRPM4 regulates Akt/GSK3-β activity and enhances β-catenin signaling and cell proliferation in prostate cancer cells
Enhanced radiosensitivity at low doses of ionizing radiation (IR) (0.2 to 0.6 Gy) has been reported in several cell lines. This phenomenon, known as low doses hyperradiosensitivity (LDHRS), appears as an opportunity to decrease toxicity of radiotherapy and to enhance the effects of chemotherapy. ...
Andaur, R.
,
Tapia, J.C.
,
Moreno, J.
,
Soto, L.
,
Armisen, R.
,
Marcelain, K.
,
[Differential miRNA expression profiling reveals miR-205-3p to be a potential radiosensitizer for low- dose ionizing radiation in DLD-1 cells]
,
Differential miRNA expression profiling reveals miR-205-3p to be a potential radiosensitizer for low- dose ionizing radiation in DLD-1 cells
Plasma focus devices may arise as useful source to perform experiments aimed to study the effects of pulsed radiation on human cells in vitro. In the present work, a table top hundred joules plasma focus device, namely "PF-400J", was adapted to irradiate colorectal cancer cell line, DLD-1. For pu...
Jain, J.
,
Moreno, J.
,
Andaur, R.
,
Armisen, R.
,
Morales, D.
,
Marcelain, K.
,
Avaria, G.
,
Bora, B.
,
Davis, S.
,
Pavez, C.
,
Soto, L.
,
[Hundred joules plasma focus device as a potential pulsed source for in vitro cancer cell irradiation]
,
Hundred joules plasma focus device as a potential pulsed source for in vitro cancer cell irradiation