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The aim of this study was to assess, whether polymerase chain reaction (PCR) allows sensitive screening of treatment failure suspicions in areas, where drug resistance against African animal trypanosomosis (AAT) appears to be a problem. PCR was used to detect trypanosome infections prior to, 14 ...


Gall, Y.Woitag, T.Bauer, B.Sidibe, I.McDermott, John J.Mehlitz, D.Clausen, P.H.[Trypanocidal failure suggested by PCR results in cattle field samples]Trypanocidal failure suggested by PCR results in cattle field samples

Drug resistant trypanosome infections in livestock have been Reported from 13 sub-Saharan countries so far, in eight of which multiple resistance occurs. Since new trypanocides are unlikely to appear on the market in the near future, information about the occurrence, extent and impact of drug res...


Gall, Y.Woitag, J.Bauer, B.Sidibe, I.McDermott, John J.Eisler, M.C.Mehlitz, D.Clausen, P.H.[Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods]Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods

Currently in Southeast Uganda, FITCA (EU funded Farming in Tsetse Controlled Areas Project) is involved in an intervention programme against both animal trypanosomiasis and human sleeping sickness. This is a regional project involving Kenya, Ethiopia, Tanzania and Uganda. In southeast Uganda, the...


Fyfe. K.Picozzi, K.Fèvre, Eric M.Wasiwa, C.McDermott, John J.Welburn, S.C.[Assessment of trypanosome prevalence in FITCA high risk areas]Assessment of trypanosome prevalence in FITCA high risk areas

A one-year longitudinal study was conducted in 92 smallholder diary farms in Kwale district of Kenya, to evaluate the efficacy of Spot-on® (a 10% deltamethrin pour-on) in the control of East Coast fever, anaplasmosis, babesiosis and trypanosomosis. A comparison of the annual incidence and mortali...


Muraguri, G.R.McLeod, A.McDermott, John J.[Efficacy of a deltamethrin-based pour-on in the control of tick-borne diseases and trypanosomosis in Kwale District, Kenya]Efficacy of a deltamethrin-based pour-on in the control of tick-borne diseases and trypanosomosis in Kwale District, Kenya

In Kenya, the vast majority of dairy farms are owned and run by smallholder farmers. These farms are estimated to produce 75-90 percent of the milk sold in Kenya (Mbogoh, 1984a, b); about 65 percent of dairy cattle in the smallholder farms are stall-fed for the greater part of the year (Gitau et ...


Gitau, G.K.Perry, Brian D.McDermott, John J.Katende, J.M.Maribei, J.M.[Risk factors associated with Theileria parva infection in cattle in smallholder dairy farms in Muranga District, Kenya. A longitudinal study]Risk factors associated with Theileria parva infection in cattle in smallholder dairy farms in Muranga District, Kenya. A longitudinal study

Tsetse-transmitted trypanosomosis affects cattle production over approximately 10 million km2 of Africa. In these areas, trypanocidal drugs, both prophylactic and curative, are the most widely used methods of trypanosomosis control. However, resistance of trypanosomes to the 3 trypanocidal drugs ...


McDermott, John J.Coleman, P.G.Eisler, M.C.Peregrine, A.S.[The effects of resistance to trypanocidal drugs on trypanosome transmission]The effects of resistance to trypanocidal drugs on trypanosome transmission
Coleman, P.G.McDermott, John J.Maudlin, I.[The public health impact of controlling Trypanosoma brucei rhodesiense in cattle]The public health impact of controlling Trypanosoma brucei rhodesiense in cattle

Bovine trypanosomiasis caused by pathogenic trypanosomes, and cyclically transmitted by tsetse flies, is considered to be a major disease constraint to livestock production in sub-Saharan Africa, preventing full use of the land to feed the rapidly increasing human population. Privatisation of vet...


Machila, N.Eisler, M.C.Wanyangu, S.W.McDermott, John J.Welburn, S.C.Maudlin, I.[Cattle owners' perceptions of African bovine trypanosomiasis and its control in Busia and Kwale districts of Kenya]Cattle owners' perceptions of African bovine trypanosomiasis and its control in Busia and Kwale districts of Kenya

The extent and significance of trypanocidal drug resistance was investigated in priority areas of three East and Southern African Countries under a project. The project was built on the results of two previous projects. Existing methods currently available for the demonstration of drug-resistance...


Eisler, M.C.Ndung'u, J.M.Murilla, G.Mdachi, R.M.Mbwambo, H.Sinyangwe, L.Machila, N.Delespaux, V.Geerts, S.Brandt, J.Peregrine, A.S.McDermott, John J.Holmes, P.H.[Area-wide appraisal of drug resistance in trypanosomes infecting cattle in East and Southern Africa]Area-wide appraisal of drug resistance in trypanosomes infecting cattle in East and Southern Africa

We conducted a field trial among Maasai cattle-keepers in Nkuruman and Nkineji areas of Kenya to evaluate the effectiveness of a synthetic tsetse-repellent technology developed for the control of trypanosomosis in cattle. The technology was a repellent (2-methoxy 4-methylphenol) emitted from disp...


Bett, Bernard K.Randolph, Thomas F.Irungu, P.Nyamwaro, Sospeter S.Kitala, P.Gathuma, J.Grace, DeliaVale, G.Hargrove, J.McDermott, John J.[Field trial of a synthetic tsetse-repellent technology developed for the control of bovine trypanosomosis in Kenya]Field trial of a synthetic tsetse-repellent technology developed for the control of bovine trypanosomosis in Kenya

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