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Conference Paper 2001

Autor: Geerts, S. Ndung'u, J.M. Murilla, G. Mbwambo, H. Sinyangwe, L. Machila, N. Delespaux, V. Brandt, J. Peregrine, A.S. McDermott, John J. Holmes, P.H. Eisler, M.C.

Testing of trypanocidal drug sensitivity in stabilates of pathogenic trypanosomes derived from cattle continues to be problematic, in spite of Development of in vitro techniques, since these are generally complicated and costly for the resources available in developing country laboratories. Furth...

Enlace original: https://cgspace.cgiar.org/handle/10568/50111

Investigación en Agricultura
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Geerts, S. ,  Ndung'u, J.M. ,  Murilla, G. ,  Mbwambo, H. ,  Sinyangwe, L. ,  Machila, N. ,  Delespaux, V. ,  Brandt, J. ,  Peregrine, A.S. ,  McDermott, John J. ,  Holmes, P.H. ,  Eisler, M.C. ,  [A simplified cost-effective method for area-wide testing of trypanocidal drug sensitivity of T. congolense in mice] ,  A simplified cost-effective method for area-wide testing of trypanocidal drug sensitivity of T. congolense in mice
Conference Paper 2003

Autor: Gall, Y. Woitag, J. Bauer, B. Sidibe, I. McDermott, John J. Eisler, M.C. Mehlitz, D. Clausen, P.H.

Drug resistant trypanosome infections in livestock have been Reported from 13 sub-Saharan countries so far, in eight of which multiple resistance occurs. Since new trypanocides are unlikely to appear on the market in the near future, information about the occurrence, extent and impact of drug res...

Enlace original: https://cgspace.cgiar.org/handle/10568/50366

Investigación en Agricultura
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Gall, Y. ,  Woitag, J. ,  Bauer, B. ,  Sidibe, I. ,  McDermott, John J. ,  Eisler, M.C. ,  Mehlitz, D. ,  Clausen, P.H. ,  [Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods] ,  Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods
Conference Paper 2000

Autor: Eisler, M.C. McDermott, John J. Mdachi, R. Murilla, G. Sinyangwe, L. Mubanga, J. Machila, N. Mbwambo, H. Coleman, P.G. Clausen, P.H. Bauer, B. Sidibe, I. Geerts, S. Holmes, P.H. Peregrine, A.S.

Trypanocidal drugs are the most widely applied method of trypanosomosis control in Africa and the only control method in Latin America and Asia . Treatment recommendations and strategies for chemotherapeutic control of trypanosomosis depends on information of trypanosomosis risk and the prevalenc...

Enlace original: https://cgspace.cgiar.org/handle/10568/51007

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Eisler, M.C. ,  McDermott, John J. ,  Mdachi, R. ,  Murilla, G. ,  Sinyangwe, L. ,  Mubanga, J. ,  Machila, N. ,  Mbwambo, H. ,  Coleman, P.G. ,  Clausen, P.H. ,  Bauer, B. ,  Sidibe, I. ,  Geerts, S. ,  Holmes, P.H. ,  Peregrine, A.S. ,  [Rapid method for the assessment of trypanocidal drug resistance in the field] ,  Rapid method for the assessment of trypanocidal drug resistance in the field
Conference Paper 2000

Autor: Coleman, P.G. Eisler, M.C. McDermott, John J. Murphy, N.B. Majiwa, P.A.O. Peregrine, A.S.

Chemotherapy is the single most important strategy for the control of trypanosomosis in African livestock. Trypanocidal drug resistance is a growing problem across much of sub-Saharan Africa and increasingly recognised as a major threat to livestock production. It is therefore of pressing importa...

Enlace original: https://cgspace.cgiar.org/handle/10568/51015

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Coleman, P.G. ,  Eisler, M.C. ,  McDermott, John J. ,  Murphy, N.B. ,  Majiwa, P.A.O. ,  Peregrine, A.S. ,  [Relative fitness in laboratory mice of drug resistant and drug-sensitive field isolates of Trypanosoma congolense] ,  Relative fitness in laboratory mice of drug resistant and drug-sensitive field isolates of Trypanosoma congolense
Conference Paper 2000

Autor: McDermott, John J. Coleman, P.G. Eisler, M.C. Peregrine, A.S.

Tsetse-transmitted trypanosomosis affects cattle production over approximately 10 million km2 of Africa. In these areas, trypanocidal drugs, both prophylactic and curative, are the most widely used methods of trypanosomosis control. However, resistance of trypanosomes to the 3 trypanocidal drugs ...

Enlace original: https://cgspace.cgiar.org/handle/10568/51156

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McDermott, John J. ,  Coleman, P.G. ,  Eisler, M.C. ,  Peregrine, A.S. ,  [The effects of resistance to trypanocidal drugs on trypanosome transmission] ,  The effects of resistance to trypanocidal drugs on trypanosome transmission
Conference Paper 2000

Autor: Coleman, P.G. McDermott, John J.

The identification and tracking of sub-populations through time and space are critical to fully understanding the epidemiology of parasitic diseases. However, very little is known about the structure, distribution and dynamics of trypanosome populations in the field. Most laboratory studies that ...

Enlace original: https://cgspace.cgiar.org/handle/10568/51267

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Coleman, P.G. ,  McDermott, John J. ,  [Trypanosome population biology - an approach to support the control of drug resistance and integrated trypanosomosis control] ,  Trypanosome population biology - an approach to support the control of drug resistance and integrated trypanosomosis control
Conference Paper 2000

Autor: Eisler, M.C. Ndung'u, J.M. Murilla, G. Mdachi, R.M. Mbwambo, H. Sinyangwe, L. Machila, N. Delespaux, V. Geerts, S. Brandt, J. Peregrine, A.S. McDermott, John J. Holmes, P.H.

The extent and significance of trypanocidal drug resistance was investigated in priority areas of three East and Southern African Countries under a project. The project was built on the results of two previous projects. Existing methods currently available for the demonstration of drug-resistance...

Enlace original: https://cgspace.cgiar.org/handle/10568/50192

Investigación en Agricultura
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Eisler, M.C. ,  Ndung'u, J.M. ,  Murilla, G. ,  Mdachi, R.M. ,  Mbwambo, H. ,  Sinyangwe, L. ,  Machila, N. ,  Delespaux, V. ,  Geerts, S. ,  Brandt, J. ,  Peregrine, A.S. ,  McDermott, John J. ,  Holmes, P.H. ,  [Area-wide appraisal of drug resistance in trypanosomes infecting cattle in East and Southern Africa] ,  Area-wide appraisal of drug resistance in trypanosomes infecting cattle in East and Southern Africa
Conference Paper 2000

Autor: McDermott, John J. Sidibe, I. Bauer, B. Diarra, B. Clausen, P.H. Woitay, T. Ouédraogo, T. Kamuanga, M. Peregrine, A.S. Eisler, M.C. Mehlitz, D.

To investigate the importance of trypanosomosis, resistance to trypanocidal drugs and the potential impact of integrated control measures on these factors, a 3-phase study was initiated. The first phase was a cross-sectional study in which tsetse apparent density, cattle trypanosome prevalence, t...

Enlace original: https://cgspace.cgiar.org/handle/10568/50551

Investigación en Agricultura
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McDermott, John J. ,  Sidibe, I. ,  Bauer, B. ,  Diarra, B. ,  Clausen, P.H. ,  Woitay, T. ,  Ouédraogo, T. ,  Kamuanga, M. ,  Peregrine, A.S. ,  Eisler, M.C. ,  Mehlitz, D. ,  [Field studies on the Development and impact of drug resistant animal trypanosomes in market oriented production systems in the Southern Guinean zone of West Africa] ,  Field studies on the Development and impact of drug resistant animal trypanosomes in market oriented production systems in the Southern Guinean zone of West Africa
Conference Paper 2000

Autor: Geerts, S. Ndung'u, J.M. Murilla, G. Mbwambo, H. Sirryangwe, L. Machila, N. Delespaux, V. Brandt, J. Peregrine, A.S. McDermott, John J. Holmes, P.H. Eisler, M.C.

Besides the in vitro test, two tests are very commonly used for the detection of trypanocidal drug resistance: the tests in mice and in ruminants. Since it has been shown that several parameters such as the number of trypanosomes inoculated and the time of treatment might influence the outcome of...

Enlace original: https://cgspace.cgiar.org/handle/10568/50712

Investigación en Agricultura
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Geerts, S. ,  Ndung'u, J.M. ,  Murilla, G. ,  Mbwambo, H. ,  Sirryangwe, L. ,  Machila, N. ,  Delespaux, V. ,  Brandt, J. ,  Peregrine, A.S. ,  McDermott, John J. ,  Holmes, P.H. ,  Eisler, M.C. ,  [In vivo tests for the detection of resistance to trypanocidal drugs: Tests in mice and in ruminants] ,  In vivo tests for the detection of resistance to trypanocidal drugs: Tests in mice and in ruminants

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