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Journal Article 2011-09-29

Autor: Nkando, I. Ndinda, J. Kuria, J. Naessens, Jan Mbithi, F. Schnier, C. Gicheru, M. McKeever, Declan J. Wesonga, H.O.

A live, attenuated vaccine is currently the only viable option to control of CBPP in Africa. It has been suggested that simple modifications to current vaccines and protocols might improve efficacy in the field. In this report we compared the current vaccine formulation with a buffered preparatio...

Enlace original: https://cgspace.cgiar.org/handle/10568/16450

Investigación en Agricultura
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Nkando, I. ,  Ndinda, J. ,  Kuria, J. ,  Naessens, Jan ,  Mbithi, F. ,  Schnier, C. ,  Gicheru, M. ,  McKeever, Declan J. ,  Wesonga, H.O. ,  [Efficacy of two vaccine formulations against contagious bovine pleuropneumonia (CBPP) in Kenyan indigenous cattle] ,  Efficacy of two vaccine formulations against contagious bovine pleuropneumonia (CBPP) in Kenyan indigenous cattle
Journal Article 2005-07-01

Autor: Pain, A. Renauld, H. Berriman, M. Murphy, L. Yeats, C.A. Weir, W. Kerhornou, A. Aslett, M. Bishop, Richard P. Bouchier, C. Cochet, M. Coulson, R.M.R. Cronin, A. Villiers, Etienne P. de Fraser, A. Fosker, N. Gardner, M. Goble, A. Griffiths-Jones, S. Harris, D.E. Katzer, F. Larke, N. Lord, A. Maser, P. McKellar, S. Mooney, P. Morton, F. Nene, Vishvanath O'Neil, S. Price, C. Quail, M.A. Rabbinowitsch, E. Rawlings, N.D. Rutter, S. Saunders, D. Seeger, K. Shah, Tushaar Squares, R. Squares, S. Tivey, A. Walker, A.R. Woodward, J. Dobbelaere, D.A.E. Langsley, G. Rajandream, M.A. McKeever, Declan J. Shiels, B. Tait, A. Barrell, B. Hall, N.

Theileria annulata and T. parva are closely related protozoan parasites that cause lymphoproliferative diseases of cattle. We sequenced the genome of T. annulata and compared it with that of T. parva to understand the mechanisms underlying transformation and tropism. Despite high conservation of ...

Enlace original: https://cgspace.cgiar.org/handle/10568/21171

Investigación en Agricultura
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Pain, A. ,  Renauld, H. ,  Berriman, M. ,  Murphy, L. ,  Yeats, C.A. ,  Weir, W. ,  Kerhornou, A. ,  Aslett, M. ,  Bishop, Richard P. ,  Bouchier, C. ,  Cochet, M. ,  Coulson, R.M.R. ,  Cronin, A. ,  Villiers, Etienne P. de ,  Fraser, A. ,  Fosker, N. ,  Gardner, M. ,  Goble, A. ,  Griffiths-Jones, S. ,  Harris, D.E. ,  Katzer, F. ,  Larke, N. ,  Lord, A. ,  Maser, P. ,  McKellar, S. ,  Mooney, P. ,  Morton, F. ,  Nene, Vishvanath ,  O'Neil, S. ,  Price, C. ,  Quail, M.A. ,  Rabbinowitsch, E. ,  Rawlings, N.D. ,  Rutter, S. ,  Saunders, D. ,  Seeger, K. ,  Shah, Tushaar ,  Squares, R. ,  Squares, S. ,  Tivey, A. ,  Walker, A.R. ,  Woodward, J. ,  Dobbelaere, D.A.E. ,  Langsley, G. ,  Rajandream, M.A. ,  McKeever, Declan J. ,  Shiels, B. ,  Tait, A. ,  Barrell, B. ,  Hall, N. ,  [Genome of the host-cell transforming parasite Theileria annulata compared with T. parva] ,  Genome of the host-cell transforming parasite Theileria annulata compared with T. parva
Journal Article 1997

Autor: Ballingall, K.T. Luyai, A. McKeever, Declan J.

We describe the development of a polymerase chain reaction (PCR)-based approach for analysis of genetic diversity at the DQA loci in African Bos indicus and Bos Taurus cattle. This approach, equally effective in European and Asian cattle breeds, detects the presence or absence of DAQ1 and most du...

Enlace original: https://cgspace.cgiar.org/handle/10568/32942

Investigación en Agricultura
DNA
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Ballingall, K.T. ,  Luyai, A. ,  McKeever, Declan J. ,  [Analysis of genetic diversity at the DQA loci in African cattle: Evidence for a BoLA-DQA3 locus] ,  Analysis of genetic diversity at the DQA loci in African cattle: Evidence for a BoLA-DQA3 locus
Journal Article 1999

Autor: Daubenberger, C.A. Taracha, E.L.N. Gaidulis, L. Davis, W.C. McKeever, Declan J.

T cells bearing the gamma delta antigen receptor (gamma delta T cells) can constitute up to 50 percent of T cells in the peripheral blood and lymphoid organs of young cattle. We present data showing that gamma delta T cells are involved in immune responses against Theileria parva. Gamma delta T c...

Enlace original: https://cgspace.cgiar.org/handle/10568/28767

Investigación en Agricultura
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Daubenberger, C.A. ,  Taracha, E.L.N. ,  Gaidulis, L. ,  Davis, W.C. ,  McKeever, Declan J. ,  [Bovine gamma delta T cell responses to the intracellular protozoan parasite Theileria parva] ,  Bovine gamma delta T cell responses to the intracellular protozoan parasite Theileria parva
Journal Article 1999

Autor: Ellis, S.A. Holmes, E.C. Staines, K.A. Smith, K.B. Stear, M.J. McKeever, Declan J. MacHugh, Niall D. Morrison, W. Ivan

Analysis of cattle major histocompatibility complex (MHC) (BoLA) class I gene expression using serological and biochemical methods has demonstrated a high level of polymorphism. However, analysis of class I cDNA sequences has failed to produce conclusive evidence concerning the number and nature ...

Enlace original: https://cgspace.cgiar.org/handle/10568/32939

Investigación en Agricultura
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Ellis, S.A. ,  Holmes, E.C. ,  Staines, K.A. ,  Smith, K.B. ,  Stear, M.J. ,  McKeever, Declan J. ,  MacHugh, Niall D. ,  Morrison, W. Ivan ,  [Variation in the number of expressed MHC genes in different cattle class I haplotypes] ,  Variation in the number of expressed MHC genes in different cattle class I haplotypes
Journal Article 2001

Autor: Ballingall, K.T. Waibochi, L. Homes, E.C. Woelk, C.H. MacHugh, Niall D. Lutje, V. McKeever, Declan J.

Cattle in Africa are a genetically diverse population that has resulted from successive introduction of Asian Bos indicus and European B. Taurus cattle. However, analysis of mitochondrial genetic diversity in African cattle identified three lineages, one associated with Asian B. indicus, one with...

Enlace original: https://cgspace.cgiar.org/handle/10568/32940

Investigación en Agricultura
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Ballingall, K.T. ,  Waibochi, L. ,  Homes, E.C. ,  Woelk, C.H. ,  MacHugh, Niall D. ,  Lutje, V. ,  McKeever, Declan J. ,  [The CD45 locus in cattle: Allelic polymorphism and evidence for exceptional positive natural selection] ,  The CD45 locus in cattle: Allelic polymorphism and evidence for exceptional positive natural selection
Journal Article 2009-09-15

Autor: MacHugh, Niall D. Connelley, T. Graham, S.P. Pelle, Roger Formisano, P. Taracha, E.L.N. Ellis, S.A. McKeever, Declan J. Burrells, A. Morrison, W. Ivan

Although immunodominance of CD8+ T-cell responses is a well-recognised feature of viral infections, its role in responses to more antigenically complex pathogens is less clear. In previous studies we have observed that CD8+ T-cell responses to Theileria parva exhibit different patterns of parasit...

Enlace original: https://cgspace.cgiar.org/handle/10568/342

Investigación en Agricultura
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MacHugh, Niall D. ,  Connelley, T. ,  Graham, S.P. ,  Pelle, Roger ,  Formisano, P. ,  Taracha, E.L.N. ,  Ellis, S.A. ,  McKeever, Declan J. ,  Burrells, A. ,  Morrison, W. Ivan ,  [CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity] ,  CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity
Journal Article 1991

Autor: Goddeeris, B.M. Dunlap, S. Innes, E.A. McKeever, Declan J.
Enlace original: https://cgspace.cgiar.org/handle/10568/29463

Investigación en Agricultura
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Goddeeris, B.M. ,  Dunlap, S. ,  Innes, E.A. ,  McKeever, Declan J. ,  [A simple and efficient method for purifying and quantifying schizonts from Theileria parva-infected cells] ,  A simple and efficient method for purifying and quantifying schizonts from Theileria parva-infected cells
Journal Article 1998

Autor: Honda, Y. Waithaka, M.M. Taracha, E.L.N. Duchateau, L. Musoke, A.J. McKeever, Declan J.

To evaluate vaccinia virus as a delivery system for recombinant antigen in cattle, calves were immunized with a recombinant vaccinia virus (rVV) expressing the sporozoite surface antigen (p67) of Theileria parva (V-67) combined with those expressing bovine IL-4 (V-IL4) or IL-2 (V-IL2). The anti-p...

Enlace original: https://cgspace.cgiar.org/handle/10568/29820

Investigación en Agricultura
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Honda, Y. ,  Waithaka, M.M. ,  Taracha, E.L.N. ,  Duchateau, L. ,  Musoke, A.J. ,  McKeever, Declan J. ,  [Delivery of the Theileria parva p67 antigen to cattle using recombinant vaccinia virus: IL-2 enhances protection] ,  Delivery of the Theileria parva p67 antigen to cattle using recombinant vaccinia virus: IL-2 enhances protection
Journal Article 1998

Autor: Heussler, V.T. Taracha, E.L.N. Musoke, A.J. Duchateau, L. McKeever, Declan J.

Cattle immunised with a recombinant form of p67, the major surface antigen of Theilleria parva sporozoites, have been shown to be protected against parasite challenge. In an attempt to simplify the immunisation procedure live attenuated Salmonella strains expressing p67 have been constructed and ...

Enlace original: https://cgspace.cgiar.org/handle/10568/35341

Investigación en Agricultura
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Heussler, V.T. ,  Taracha, E.L.N. ,  Musoke, A.J. ,  Duchateau, L. ,  McKeever, Declan J. ,  [Immunisation with live attenuated Salmonella dublin expressing a sporozoite protein confers partial protection against Theileria parva] ,  Immunisation with live attenuated Salmonella dublin expressing a sporozoite protein confers partial protection against Theileria parva

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